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4UJ5

Crystal structure of human Rab11-Rabin8-FIP3

Functional Information from GO Data
ChainGOidnamespacecontents
A0003924molecular_functionGTPase activity
A0005525molecular_functionGTP binding
B0003924molecular_functionGTPase activity
B0005525molecular_functionGTP binding
C0005085molecular_functionguanyl-nucleotide exchange factor activity
D0005085molecular_functionguanyl-nucleotide exchange factor activity
Functional Information from PDB Data
site_idAC1
Number of Residues27
DetailsBINDING SITE FOR RESIDUE GNP A 201
ChainResidue
ASER20
ALEU38
ASER40
ASER42
ATHR43
AALA68
AGLY69
AASN124
ALYS125
AASP127
ALEU128
AGLY21
ASER154
AALA155
ALEU156
AMG202
AHOH2006
AHOH2007
AHOH2027
CTYR423
AVAL22
AGLY23
ALYS24
ASER25
AASN26
APHE36
AASN37

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG A 202
ChainResidue
ASER25
ATHR43
AASP66
AGNP201
AHOH2006
AHOH2007

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 A 203
ChainResidue
AASP92
AALA94
ALYS95
ALYS125

site_idAC4
Number of Residues27
DetailsBINDING SITE FOR RESIDUE GNP B 201
ChainResidue
BSER20
BGLY21
BVAL22
BGLY23
BLYS24
BSER25
BASN26
BPHE36
BASN37
BLEU38
BSER40
BSER42
BTHR43
BTHR67
BALA68
BGLY69
BASN124
BLYS125
BASP127
BLEU128
BSER154
BALA155
BLEU156
BMG202
BHOH2006
BHOH2007
DTYR423

site_idAC5
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG B 202
ChainResidue
BSER25
BTHR43
BGNP201
BHOH2006
BHOH2007

Functional Information from PROSITE/UniProt
site_idPS00014
Number of Residues4
DetailsER_TARGET Endoplasmic reticulum targeting sequence. KEEL
ChainResidueDetails
CLYS457-LEU460

site_idPS00675
Number of Residues14
DetailsSIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. VVLiGDSGVGKsnL
ChainResidueDetails
AVAL14-LEU27

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
CSER272
DSER272
ASER154
BGLY18
BASN124
BSER154

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q68EF0
ChainResidueDetails
CSER280
DSER280

site_idSWS_FT_FI3
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:16905101, ECO:0000269|PubMed:17007872, ECO:0000269|PubMed:17030804, ECO:0007744|PDB:1OIW, ECO:0007744|PDB:4D0L, ECO:0007744|PDB:4D0M, ECO:0007744|PDB:5C46, ECO:0007744|PDB:5FBL
ChainResidueDetails
AASP66
BASP66

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PDB entries from 2024-10-30

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