Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEM A 750 |
| Chain | Residue |
| A | TRP414 |
| A | TRP683 |
| A | PHE709 |
| A | TYR711 |
| A | H4B760 |
| A | OLW800 |
| A | HOH2142 |
| A | HOH2154 |
| A | HOH2202 |
| A | HOH2203 |
| A | ARG419 |
| A | CYS420 |
| A | VAL421 |
| A | GLY422 |
| A | PHE589 |
| A | SER590 |
| A | TRP592 |
| A | GLU597 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE H4B A 760 |
| Chain | Residue |
| A | SER339 |
| A | MET341 |
| A | ARG601 |
| A | VAL682 |
| A | TRP683 |
| A | HEM750 |
| A | HOH2014 |
| A | HOH2154 |
| A | HOH2155 |
| A | HOH2190 |
| A | HOH2204 |
| B | TRP681 |
| B | PHE696 |
| B | HIS697 |
| B | GLN698 |
| B | GLU699 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE OLW A 800 |
| Chain | Residue |
| A | MET341 |
| A | HIS342 |
| A | GLN483 |
| A | PRO570 |
| A | VAL572 |
| A | TYR711 |
| A | HEM750 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 900 |
| Chain | Residue |
| A | CYS331 |
| A | CYS336 |
| B | CYS331 |
| B | CYS336 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE HEM B 750 |
| Chain | Residue |
| B | TRP414 |
| B | CYS420 |
| B | SER462 |
| B | PHE589 |
| B | SER590 |
| B | TRP592 |
| B | GLU597 |
| B | TRP683 |
| B | PHE709 |
| B | TYR711 |
| B | H4B760 |
| B | OLW800 |
| B | HOH2108 |
| B | HOH2139 |
| B | HOH2140 |
| B | HOH2141 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE H4B B 760 |
| Chain | Residue |
| A | TRP681 |
| A | PHE696 |
| A | HIS697 |
| A | GLN698 |
| A | GLU699 |
| B | SER339 |
| B | MET341 |
| B | ARG601 |
| B | VAL682 |
| B | TRP683 |
| B | HEM750 |
| B | HOH2027 |
| B | HOH2120 |
| B | HOH2134 |
| B | HOH2140 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE OLW B 800 |
| Chain | Residue |
| B | MET341 |
| B | HIS342 |
| B | GLN483 |
| B | PRO570 |
| B | VAL572 |
| B | TRP683 |
| B | TYR711 |
| B | HEM750 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
| Chain | Residue | Details |
| A | ARG419-TRP426 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25286850","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4D1N","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"25286850","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4D1N","evidenceCode":"ECO:0007744"}]} |
