4UC1

High resolution crystal structure of translocator protein 18kDa (TSPO) from Rhodobacter sphaeroides (A139T Mutant) in C2 space group

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0008289	molecular_function	lipid binding
A	0016020	cellular_component	membrane
A	0033013	biological_process	tetrapyrrole metabolic process
A	0042802	molecular_function	identical protein binding
A	0046906	molecular_function	tetrapyrrole binding
B	0005886	cellular_component	plasma membrane
B	0008289	molecular_function	lipid binding
B	0016020	cellular_component	membrane
B	0033013	biological_process	tetrapyrrole metabolic process
B	0042802	molecular_function	identical protein binding
B	0046906	molecular_function	tetrapyrrole binding
C	0005886	cellular_component	plasma membrane
C	0008289	molecular_function	lipid binding
C	0016020	cellular_component	membrane
C	0033013	biological_process	tetrapyrrole metabolic process
C	0042802	molecular_function	identical protein binding
C	0046906	molecular_function	tetrapyrrole binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue OLC A 201

Chain	Residue
A	ASN2
A	MET3
A	LEU59
A	MET62
A	ARG63
A	OLC202
A	OLC206
C	PHE119
C	ILE134

---

site_id	AC2
Number of Residues	5
Details	binding site for residue OLC A 202

Chain	Residue
A	TRP124
A	PRO131
A	OLC201
A	OLC206
C	TRP124

---

site_id	AC3
Number of Residues	4
Details	binding site for residue OLC A 203

Chain	Residue
A	PHE119
A	GLN120
A	OLC205
A	HOH302

---

site_id	AC4
Number of Residues	7
Details	binding site for residue OLC A 204

Chain	Residue
A	PRO42
A	TRP44
A	OLC206
B	PRO42
B	TRP44
B	OLC204
C	TRP44

---

site_id	AC5
Number of Residues	6
Details	binding site for residue OLC A 205

Chain	Residue
A	TRP39
A	TRP108
A	THR137
A	THR140
A	GLY141
A	OLC203

---

site_id	AC6
Number of Residues	7
Details	binding site for residue OLC A 206

Chain	Residue
A	TRP38
A	TRP39
A	ASN40
A	OLC201
A	OLC202
A	OLC204
B	OLC204

---

site_id	AC7
Number of Residues	18
Details	binding site for residue PP9 A 207

Chain	Residue
A	PRO18
A	ALA19
A	GLY22
A	ALA23
A	ARG43
A	PHE46
A	PRO47
A	TRP50
A	TYR54
A	ASN84
A	TRP87
A	THR88
A	PHE92
A	TRP135
A	THR139
C	TRP38
C	TRP39
C	GLU145

---

site_id	AC8
Number of Residues	5
Details	binding site for residue OLC B 201

Chain	Residue
B	ASP4
B	TRP5
B	ALA6
B	LEU12
B	OLC202

---

site_id	AC9
Number of Residues	6
Details	binding site for residue OLC B 202

Chain	Residue
A	GLN72
A	PHE110
B	ALA6
B	THR10
B	ALA13
B	OLC201

---

site_id	AD1
Number of Residues	10
Details	binding site for residue OLC B 203

Chain	Residue
B	TRP108
B	MET115
B	TRP116
B	PHE119
B	GLN120
B	THR123
B	OLC206
C	MET3
C	TRP5
C	P4C205

---

site_id	AD2
Number of Residues	3
Details	binding site for residue OLC B 204

Chain	Residue
A	OLC204
A	OLC206
B	TRP44

---

site_id	AD3
Number of Residues	4
Details	binding site for residue OLC B 205

Chain	Residue
B	PHE144
B	MET147
B	ARG148
B	TRP151

---

site_id	AD4
Number of Residues	3
Details	binding site for residue OLC B 206

Chain	Residue
B	MET105
B	TRP108
B	OLC203

---

site_id	AD5
Number of Residues	3
Details	binding site for residue OLC B 207

Chain	Residue
A	GLU29
B	LEU59
B	TRP124

---

site_id	AD6
Number of Residues	9
Details	binding site for residue Z0P B 208

Chain	Residue
A	ALA6
A	LEU9
A	THR10
A	ALA13
B	PHE76
B	PHE83
B	PHE110
B	ALA113
B	TRP116

---

site_id	AD7
Number of Residues	10
Details	binding site for residue OLC C 201

Chain	Residue
C	ALA6
C	THR10
C	ALA13
C	GLN72
C	TRP116
C	OLC203
C	P4C205
C	HOH302
C	HOH314
C	HOH322

---

site_id	AD8
Number of Residues	5
Details	binding site for residue OLC C 202

Chain	Residue
A	TRP5
C	TRP108
C	LEU109
C	TRP116
C	OLC203

---

site_id	AD9
Number of Residues	7
Details	binding site for residue OLC C 203

Chain	Residue
C	PHE83
C	ALA102
C	LEU109
C	PHE110
C	TRP116
C	OLC201
C	OLC202

---

site_id	AE1
Number of Residues	13
Details	binding site for residue OLC C 204

Chain	Residue
B	TRP38
B	TRP39
B	PRO41
B	VAL45
C	ALA19
C	LEU25
C	LYS26
C	PHE46
C	PRO47
C	TRP50
C	TYR54
C	PHE92
C	P4C205

---

site_id	AE2
Number of Residues	7
Details	binding site for residue P4C C 205

Chain	Residue
B	THR137
B	OLC203
C	TRP5
C	THR51
C	PHE55
C	OLC201
C	OLC204

---

site_id	AE3
Number of Residues	4
Details	binding site for residue MOE C 206

Chain	Residue
C	LEU67
C	GLU68
C	GLU68
C	GLY69

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	60
Details	Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"25635101","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	63
Details	Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"25635101","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	60
Details	Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"25635101","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	66
Details	Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"25635101","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	60
Details	Transmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"25635101","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---