4U8U

The Crystallographic structure of the giant hemoglobin from Glossoscolex paulistus at 3.2 A resolution.

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0001666	biological_process	response to hypoxia
a	0005344	molecular_function	oxygen carrier activity
a	0005506	molecular_function	iron ion binding
a	0005576	cellular_component	extracellular region
a	0005833	cellular_component	hemoglobin complex
a	0015671	biological_process	oxygen transport
a	0019825	molecular_function	oxygen binding
a	0020037	molecular_function	heme binding
a	0046872	molecular_function	metal ion binding
A	0005344	molecular_function	oxygen carrier activity
A	0005506	molecular_function	iron ion binding
A	0005576	cellular_component	extracellular region
A	0005833	cellular_component	hemoglobin complex
A	0015671	biological_process	oxygen transport
A	0019825	molecular_function	oxygen binding
A	0020037	molecular_function	heme binding
A	0046872	molecular_function	metal ion binding
b	0046872	molecular_function	metal ion binding
B	0001666	biological_process	response to hypoxia
B	0005344	molecular_function	oxygen carrier activity
B	0005506	molecular_function	iron ion binding
B	0005576	cellular_component	extracellular region
B	0005833	cellular_component	hemoglobin complex
B	0015671	biological_process	oxygen transport
B	0019825	molecular_function	oxygen binding
B	0020037	molecular_function	heme binding
B	0046872	molecular_function	metal ion binding
c	0046872	molecular_function	metal ion binding
C	0001666	biological_process	response to hypoxia
C	0005344	molecular_function	oxygen carrier activity
C	0005506	molecular_function	iron ion binding
C	0005576	cellular_component	extracellular region
C	0005833	cellular_component	hemoglobin complex
C	0015671	biological_process	oxygen transport
C	0019825	molecular_function	oxygen binding
C	0020037	molecular_function	heme binding
C	0046872	molecular_function	metal ion binding
d	0046872	molecular_function	metal ion binding
D	0001666	biological_process	response to hypoxia
D	0005344	molecular_function	oxygen carrier activity
D	0005506	molecular_function	iron ion binding
D	0005576	cellular_component	extracellular region
D	0005833	cellular_component	hemoglobin complex
D	0015671	biological_process	oxygen transport
D	0019825	molecular_function	oxygen binding
D	0020037	molecular_function	heme binding
D	0046872	molecular_function	metal ion binding
e	0005344	molecular_function	oxygen carrier activity
e	0005506	molecular_function	iron ion binding
e	0005576	cellular_component	extracellular region
e	0005833	cellular_component	hemoglobin complex
e	0015671	biological_process	oxygen transport
e	0019825	molecular_function	oxygen binding
e	0020037	molecular_function	heme binding
e	0046872	molecular_function	metal ion binding
E	0005344	molecular_function	oxygen carrier activity
E	0005506	molecular_function	iron ion binding
E	0005576	cellular_component	extracellular region
E	0005833	cellular_component	hemoglobin complex
E	0015671	biological_process	oxygen transport
E	0019825	molecular_function	oxygen binding
E	0020037	molecular_function	heme binding
E	0046872	molecular_function	metal ion binding
f	0001666	biological_process	response to hypoxia
f	0005344	molecular_function	oxygen carrier activity
f	0005506	molecular_function	iron ion binding
f	0005576	cellular_component	extracellular region
f	0005833	cellular_component	hemoglobin complex
f	0015671	biological_process	oxygen transport
f	0019825	molecular_function	oxygen binding
f	0020037	molecular_function	heme binding
f	0046872	molecular_function	metal ion binding
F	0001666	biological_process	response to hypoxia
F	0005344	molecular_function	oxygen carrier activity
F	0005506	molecular_function	iron ion binding
F	0005576	cellular_component	extracellular region
F	0005833	cellular_component	hemoglobin complex
F	0015671	biological_process	oxygen transport
F	0019825	molecular_function	oxygen binding
F	0020037	molecular_function	heme binding
F	0046872	molecular_function	metal ion binding
g	0001666	biological_process	response to hypoxia
g	0005344	molecular_function	oxygen carrier activity
g	0005506	molecular_function	iron ion binding
g	0005576	cellular_component	extracellular region
g	0005833	cellular_component	hemoglobin complex
g	0015671	biological_process	oxygen transport
g	0019825	molecular_function	oxygen binding
g	0020037	molecular_function	heme binding
g	0046872	molecular_function	metal ion binding
G	0001666	biological_process	response to hypoxia
G	0005344	molecular_function	oxygen carrier activity
G	0005506	molecular_function	iron ion binding
G	0005576	cellular_component	extracellular region
G	0005833	cellular_component	hemoglobin complex
G	0015671	biological_process	oxygen transport
G	0019825	molecular_function	oxygen binding
G	0020037	molecular_function	heme binding
G	0046872	molecular_function	metal ion binding
h	0001666	biological_process	response to hypoxia
h	0005344	molecular_function	oxygen carrier activity
h	0005506	molecular_function	iron ion binding
h	0005576	cellular_component	extracellular region
h	0005833	cellular_component	hemoglobin complex
h	0015671	biological_process	oxygen transport
h	0019825	molecular_function	oxygen binding
h	0020037	molecular_function	heme binding
h	0046872	molecular_function	metal ion binding
H	0001666	biological_process	response to hypoxia
H	0005344	molecular_function	oxygen carrier activity
H	0005506	molecular_function	iron ion binding
H	0005576	cellular_component	extracellular region
H	0005833	cellular_component	hemoglobin complex
H	0015671	biological_process	oxygen transport
H	0019825	molecular_function	oxygen binding
H	0020037	molecular_function	heme binding
H	0046872	molecular_function	metal ion binding
i	0005344	molecular_function	oxygen carrier activity
i	0005506	molecular_function	iron ion binding
i	0005576	cellular_component	extracellular region
i	0005833	cellular_component	hemoglobin complex
i	0015671	biological_process	oxygen transport
i	0019825	molecular_function	oxygen binding
i	0020037	molecular_function	heme binding
i	0046872	molecular_function	metal ion binding
I	0005344	molecular_function	oxygen carrier activity
I	0005506	molecular_function	iron ion binding
I	0005576	cellular_component	extracellular region
I	0005833	cellular_component	hemoglobin complex
I	0015671	biological_process	oxygen transport
I	0019825	molecular_function	oxygen binding
I	0020037	molecular_function	heme binding
I	0046872	molecular_function	metal ion binding
j	0001666	biological_process	response to hypoxia
j	0005344	molecular_function	oxygen carrier activity
j	0005506	molecular_function	iron ion binding
j	0005576	cellular_component	extracellular region
j	0005833	cellular_component	hemoglobin complex
j	0015671	biological_process	oxygen transport
j	0019825	molecular_function	oxygen binding
j	0020037	molecular_function	heme binding
j	0046872	molecular_function	metal ion binding
J	0001666	biological_process	response to hypoxia
J	0005344	molecular_function	oxygen carrier activity
J	0005506	molecular_function	iron ion binding
J	0005576	cellular_component	extracellular region
J	0005833	cellular_component	hemoglobin complex
J	0015671	biological_process	oxygen transport
J	0019825	molecular_function	oxygen binding
J	0020037	molecular_function	heme binding
J	0046872	molecular_function	metal ion binding
k	0001666	biological_process	response to hypoxia
k	0005344	molecular_function	oxygen carrier activity
k	0005506	molecular_function	iron ion binding
k	0005576	cellular_component	extracellular region
k	0005833	cellular_component	hemoglobin complex
k	0015671	biological_process	oxygen transport
k	0019825	molecular_function	oxygen binding
k	0020037	molecular_function	heme binding
k	0046872	molecular_function	metal ion binding
K	0001666	biological_process	response to hypoxia
K	0005344	molecular_function	oxygen carrier activity
K	0005506	molecular_function	iron ion binding
K	0005576	cellular_component	extracellular region
K	0005833	cellular_component	hemoglobin complex
K	0015671	biological_process	oxygen transport
K	0019825	molecular_function	oxygen binding
K	0020037	molecular_function	heme binding
K	0046872	molecular_function	metal ion binding
l	0001666	biological_process	response to hypoxia
l	0005344	molecular_function	oxygen carrier activity
l	0005506	molecular_function	iron ion binding
l	0005576	cellular_component	extracellular region
l	0005833	cellular_component	hemoglobin complex
l	0015671	biological_process	oxygen transport
l	0019825	molecular_function	oxygen binding
l	0020037	molecular_function	heme binding
l	0046872	molecular_function	metal ion binding
L	0001666	biological_process	response to hypoxia
L	0005344	molecular_function	oxygen carrier activity
L	0005506	molecular_function	iron ion binding
L	0005576	cellular_component	extracellular region
L	0005833	cellular_component	hemoglobin complex
L	0015671	biological_process	oxygen transport
L	0019825	molecular_function	oxygen binding
L	0020037	molecular_function	heme binding
L	0046872	molecular_function	metal ion binding
m	0005344	molecular_function	oxygen carrier activity
m	0005506	molecular_function	iron ion binding
m	0005576	cellular_component	extracellular region
m	0005833	cellular_component	hemoglobin complex
m	0015671	biological_process	oxygen transport
m	0019825	molecular_function	oxygen binding
m	0020037	molecular_function	heme binding
m	0046872	molecular_function	metal ion binding
M	0046872	molecular_function	metal ion binding
n	0001666	biological_process	response to hypoxia
n	0005344	molecular_function	oxygen carrier activity
n	0005506	molecular_function	iron ion binding
n	0005576	cellular_component	extracellular region
n	0005833	cellular_component	hemoglobin complex
n	0015671	biological_process	oxygen transport
n	0019825	molecular_function	oxygen binding
n	0020037	molecular_function	heme binding
n	0046872	molecular_function	metal ion binding
N	0046872	molecular_function	metal ion binding
o	0001666	biological_process	response to hypoxia
o	0005344	molecular_function	oxygen carrier activity
o	0005506	molecular_function	iron ion binding
o	0005576	cellular_component	extracellular region
o	0005833	cellular_component	hemoglobin complex
o	0015671	biological_process	oxygen transport
o	0019825	molecular_function	oxygen binding
o	0020037	molecular_function	heme binding
o	0046872	molecular_function	metal ion binding
O	0046872	molecular_function	metal ion binding
p	0001666	biological_process	response to hypoxia
p	0005344	molecular_function	oxygen carrier activity
p	0005506	molecular_function	iron ion binding
p	0005576	cellular_component	extracellular region
p	0005833	cellular_component	hemoglobin complex
p	0015671	biological_process	oxygen transport
p	0019825	molecular_function	oxygen binding
p	0020037	molecular_function	heme binding
p	0046872	molecular_function	metal ion binding
P	0005344	molecular_function	oxygen carrier activity
P	0005506	molecular_function	iron ion binding
P	0005576	cellular_component	extracellular region
P	0005833	cellular_component	hemoglobin complex
P	0015671	biological_process	oxygen transport
P	0019825	molecular_function	oxygen binding
P	0020037	molecular_function	heme binding
P	0046872	molecular_function	metal ion binding
q	0046872	molecular_function	metal ion binding
Q	0001666	biological_process	response to hypoxia
Q	0005344	molecular_function	oxygen carrier activity
Q	0005506	molecular_function	iron ion binding
Q	0005576	cellular_component	extracellular region
Q	0005833	cellular_component	hemoglobin complex
Q	0015671	biological_process	oxygen transport
Q	0019825	molecular_function	oxygen binding
Q	0020037	molecular_function	heme binding
Q	0046872	molecular_function	metal ion binding
r	0046872	molecular_function	metal ion binding
R	0001666	biological_process	response to hypoxia
R	0005344	molecular_function	oxygen carrier activity
R	0005506	molecular_function	iron ion binding
R	0005576	cellular_component	extracellular region
R	0005833	cellular_component	hemoglobin complex
R	0015671	biological_process	oxygen transport
R	0019825	molecular_function	oxygen binding
R	0020037	molecular_function	heme binding
R	0046872	molecular_function	metal ion binding
s	0046872	molecular_function	metal ion binding
S	0001666	biological_process	response to hypoxia
S	0005344	molecular_function	oxygen carrier activity
S	0005506	molecular_function	iron ion binding
S	0005576	cellular_component	extracellular region
S	0005833	cellular_component	hemoglobin complex
S	0015671	biological_process	oxygen transport
S	0019825	molecular_function	oxygen binding
S	0020037	molecular_function	heme binding
S	0046872	molecular_function	metal ion binding
T	0005344	molecular_function	oxygen carrier activity
T	0005506	molecular_function	iron ion binding
T	0005576	cellular_component	extracellular region
T	0005833	cellular_component	hemoglobin complex
T	0015671	biological_process	oxygen transport
T	0019825	molecular_function	oxygen binding
T	0020037	molecular_function	heme binding
T	0046872	molecular_function	metal ion binding
U	0001666	biological_process	response to hypoxia
U	0005344	molecular_function	oxygen carrier activity
U	0005506	molecular_function	iron ion binding
U	0005576	cellular_component	extracellular region
U	0005833	cellular_component	hemoglobin complex
U	0015671	biological_process	oxygen transport
U	0019825	molecular_function	oxygen binding
U	0020037	molecular_function	heme binding
U	0046872	molecular_function	metal ion binding
V	0001666	biological_process	response to hypoxia
V	0005344	molecular_function	oxygen carrier activity
V	0005506	molecular_function	iron ion binding
V	0005576	cellular_component	extracellular region
V	0005833	cellular_component	hemoglobin complex
V	0015671	biological_process	oxygen transport
V	0019825	molecular_function	oxygen binding
V	0020037	molecular_function	heme binding
V	0046872	molecular_function	metal ion binding
W	0001666	biological_process	response to hypoxia
W	0005344	molecular_function	oxygen carrier activity
W	0005506	molecular_function	iron ion binding
W	0005576	cellular_component	extracellular region
W	0005833	cellular_component	hemoglobin complex
W	0015671	biological_process	oxygen transport
W	0019825	molecular_function	oxygen binding
W	0020037	molecular_function	heme binding
W	0046872	molecular_function	metal ion binding
X	0005344	molecular_function	oxygen carrier activity
X	0005506	molecular_function	iron ion binding
X	0005576	cellular_component	extracellular region
X	0005833	cellular_component	hemoglobin complex
X	0015671	biological_process	oxygen transport
X	0019825	molecular_function	oxygen binding
X	0020037	molecular_function	heme binding
X	0046872	molecular_function	metal ion binding
Y	0001666	biological_process	response to hypoxia
Y	0005344	molecular_function	oxygen carrier activity
Y	0005506	molecular_function	iron ion binding
Y	0005576	cellular_component	extracellular region
Y	0005833	cellular_component	hemoglobin complex
Y	0015671	biological_process	oxygen transport
Y	0019825	molecular_function	oxygen binding
Y	0020037	molecular_function	heme binding
Y	0046872	molecular_function	metal ion binding
Z	0001666	biological_process	response to hypoxia
Z	0005344	molecular_function	oxygen carrier activity
Z	0005506	molecular_function	iron ion binding
Z	0005576	cellular_component	extracellular region
Z	0005833	cellular_component	hemoglobin complex
Z	0015671	biological_process	oxygen transport
Z	0019825	molecular_function	oxygen binding
Z	0020037	molecular_function	heme binding
Z	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS01209
Number of Residues	25
Details	LDLRA_1 LDL-receptor class A (LDLRA) domain signature. CIsdlff.CDghkDCkngrDEDkev..C

Chain	Residue	Details
b	CYS76-CYS100
d	CYS73-CYS95

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