4U6C
HsMetAP in complex with [(1R)-1-amino-3-cyclopentylpropyl]phosphonic acid
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CO A 400 |
| Chain | Residue |
| A | ASP240 |
| A | HIS303 |
| A | GLU336 |
| A | GLU367 |
| A | CO401 |
| A | Q06404 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CO A 401 |
| Chain | Residue |
| A | CO400 |
| A | Q06404 |
| A | ASP229 |
| A | ASP240 |
| A | GLU367 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue K A 402 |
| Chain | Residue |
| A | GLY94 |
| A | LEU96 |
| A | GLU208 |
| A | HOH546 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| A | THR172 |
| A | THR204 |
| A | VAL206 |
| A | VAL209 |
| A | ILE214 |
| A | PRO215 |
| A | ASP216 |
| A | HOH573 |
| A | HOH586 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | binding site for residue Q06 A 404 |
| Chain | Residue |
| A | TYR195 |
| A | PHE198 |
| A | CYS203 |
| A | HIS212 |
| A | ASP229 |
| A | THR231 |
| A | ASP240 |
| A | HIS303 |
| A | PHE309 |
| A | HIS310 |
| A | GLU336 |
| A | TRP353 |
| A | GLU367 |
| A | CO400 |
| A | CO401 |
| A | HOH605 |
| A | HOH623 |
| A | HOH636 |
Functional Information from PROSITE/UniProt
| site_id | PS00680 |
| Number of Residues | 19 |
| Details | MAP_1 Methionine aminopeptidase subfamily 1 signature. YcGHGIHklfHtapnVp.HY |
| Chain | Residue | Details |
| A | TYR300-TYR318 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03174","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16724298","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16823043","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17114291","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03174","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16274222","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16724298","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16823043","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17114291","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
