4U3E
Anaerobic ribonucleotide reductase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004748 | molecular_function | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
| A | 0006260 | biological_process | DNA replication |
| A | 0008998 | molecular_function | ribonucleoside-triphosphate reductase (thioredoxin) activity |
| A | 0009265 | biological_process | 2'-deoxyribonucleotide biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0031250 | cellular_component | anaerobic ribonucleoside-triphosphate reductase complex |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004748 | molecular_function | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
| B | 0006260 | biological_process | DNA replication |
| B | 0008998 | molecular_function | ribonucleoside-triphosphate reductase (thioredoxin) activity |
| B | 0009265 | biological_process | 2'-deoxyribonucleotide biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0031250 | cellular_component | anaerobic ribonucleoside-triphosphate reductase complex |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 701 |
| Chain | Residue |
| A | CYS594 |
| A | HIS598 |
| A | CYS605 |
| A | CYS608 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue CIT A 702 |
| Chain | Residue |
| A | GLU500 |
| A | LYS501 |
| A | ALA502 |
| A | NA704 |
| A | ACT705 |
| A | HOH887 |
| A | HOH977 |
| A | HOH1150 |
| A | HOH1153 |
| A | TYR112 |
| A | HIS114 |
| A | ASP115 |
| A | HIS117 |
| A | ALA499 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 703 |
| Chain | Residue |
| A | SER146 |
| A | GLU147 |
| A | THR154 |
| A | GLN157 |
| A | HIS158 |
| A | HOH941 |
| A | HOH986 |
| A | HOH1163 |
| B | TYR214 |
| B | GLN218 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 704 |
| Chain | Residue |
| A | ASP115 |
| A | CIT702 |
| A | ACT705 |
| A | HOH1009 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue ACT A 705 |
| Chain | Residue |
| A | HIS114 |
| A | ASP115 |
| A | TYR124 |
| A | CIT702 |
| A | NA704 |
| A | HOH968 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 901 |
| Chain | Residue |
| B | CYS594 |
| B | HIS598 |
| B | CYS605 |
| B | CYS608 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | binding site for residue CIT B 902 |
| Chain | Residue |
| B | TYR112 |
| B | HIS114 |
| B | ASP115 |
| B | HIS117 |
| B | ALA499 |
| B | GLU500 |
| B | LYS501 |
| B | ALA502 |
| B | HOH1084 |
| B | HOH1116 |
| B | HOH1295 |
| B | HOH1355 |
| B | HOH1359 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 903 |
| Chain | Residue |
| A | TYR214 |
| A | GLN218 |
| A | HOH1129 |
| B | GLU147 |
| B | GLN157 |
| B | HIS158 |
| B | HOH1172 |
| B | HOH1290 |
