4U2H
The crystal structure of apo CalE6, a methionine gamma lyase from Micromonospora echinospora
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016846 | molecular_function | carbon-sulfur lyase activity |
| A | 0019346 | biological_process | transsulfuration |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016846 | molecular_function | carbon-sulfur lyase activity |
| B | 0019346 | biological_process | transsulfuration |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0016846 | molecular_function | carbon-sulfur lyase activity |
| C | 0019346 | biological_process | transsulfuration |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0016846 | molecular_function | carbon-sulfur lyase activity |
| D | 0019346 | biological_process | transsulfuration |
| D | 0030170 | molecular_function | pyridoxal phosphate binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0016846 | molecular_function | carbon-sulfur lyase activity |
| E | 0019346 | biological_process | transsulfuration |
| E | 0030170 | molecular_function | pyridoxal phosphate binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0016846 | molecular_function | carbon-sulfur lyase activity |
| F | 0019346 | biological_process | transsulfuration |
| F | 0030170 | molecular_function | pyridoxal phosphate binding |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0016846 | molecular_function | carbon-sulfur lyase activity |
| G | 0019346 | biological_process | transsulfuration |
| G | 0030170 | molecular_function | pyridoxal phosphate binding |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0016846 | molecular_function | carbon-sulfur lyase activity |
| H | 0019346 | biological_process | transsulfuration |
| H | 0030170 | molecular_function | pyridoxal phosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 401 |
| Chain | Residue |
| A | ASN147 |
| A | LYS197 |
| A | SER323 |
| A | THR338 |
| A | ARG358 |
| A | HOH729 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | THR196 |
| A | LYS197 |
| A | GLY207 |
| A | HOH774 |
| B | TYR46 |
| B | ARG48 |
| A | GLY76 |
| A | GLN77 |
| A | SER194 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue SO4 B 401 |
| Chain | Residue |
| A | TYR46 |
| A | ARG48 |
| B | SER75 |
| B | GLY76 |
| B | GLN77 |
| B | SER194 |
| B | THR196 |
| B | LYS197 |
| B | GLY207 |
| B | HOH590 |
| B | HOH620 |
| B | HOH816 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue SO4 B 402 |
| Chain | Residue |
| B | ASN147 |
| B | LYS197 |
| B | VAL322 |
| B | SER323 |
| B | LEU324 |
| B | THR338 |
| B | ARG358 |
| B | HOH637 |
| B | HOH640 |
| B | HOH768 |
| B | HOH795 |
| B | HOH825 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 C 401 |
| Chain | Residue |
| C | LYS197 |
| C | VAL322 |
| C | SER323 |
| C | LEU324 |
| C | THR338 |
| C | ARG358 |
| C | HOH612 |
| C | HOH727 |
| C | HOH800 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 C 402 |
| Chain | Residue |
| C | SER75 |
| C | GLY76 |
| C | GLN77 |
| C | SER194 |
| C | THR196 |
| C | GLY207 |
| C | HOH695 |
| C | HOH700 |
| D | TYR46 |
| D | ARG48 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 D 401 |
| Chain | Residue |
| C | TYR46 |
| C | ARG48 |
| D | SER75 |
| D | GLY76 |
| D | GLN77 |
| D | SER194 |
| D | THR196 |
| D | GLY207 |
| D | HOH602 |
| D | HOH639 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 D 402 |
| Chain | Residue |
| D | ASN147 |
| D | LYS197 |
| D | SER323 |
| D | LEU324 |
| D | THR338 |
| D | ARG358 |
| D | HOH703 |
| D | HOH723 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 E 401 |
| Chain | Residue |
| E | ASN147 |
| E | LYS197 |
| E | SER323 |
| E | LEU324 |
| E | THR338 |
| E | ARG358 |
| E | HOH762 |
| site_id | AD1 |
| Number of Residues | 11 |
| Details | binding site for residue SO4 E 402 |
| Chain | Residue |
| E | SER75 |
| E | GLY76 |
| E | GLN77 |
| E | SER194 |
| E | THR196 |
| E | GLY207 |
| E | HOH658 |
| E | HOH699 |
| E | HOH750 |
| F | TYR46 |
| F | ARG48 |
| site_id | AD2 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 F 401 |
| Chain | Residue |
| F | SER194 |
| F | THR196 |
| F | LYS197 |
| F | GLY207 |
| F | HOH586 |
| E | TYR46 |
| E | ARG48 |
| F | SER75 |
| F | GLY76 |
| F | GLN77 |
| site_id | AD3 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 F 402 |
| Chain | Residue |
| F | ASN147 |
| F | LYS197 |
| F | VAL322 |
| F | SER323 |
| F | LEU324 |
| F | THR338 |
| F | ARG358 |
| F | HOH673 |
| F | HOH720 |
| site_id | AD4 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 G 401 |
| Chain | Residue |
| G | ASN147 |
| G | LYS197 |
| G | VAL322 |
| G | SER323 |
| G | GLU332 |
| G | THR338 |
| G | ARG358 |
| G | HOH812 |
| site_id | AD5 |
| Number of Residues | 11 |
| Details | binding site for residue SO4 G 402 |
| Chain | Residue |
| G | SER75 |
| G | GLY76 |
| G | GLN77 |
| G | SER194 |
| G | THR196 |
| G | LYS197 |
| G | GLY207 |
| G | HOH586 |
| H | TYR46 |
| H | ARG48 |
| H | HOH586 |
| site_id | AD6 |
| Number of Residues | 11 |
| Details | binding site for residue SO4 G 403 |
| Chain | Residue |
| G | TYR46 |
| G | ARG48 |
| G | HOH716 |
| G | HOH792 |
| H | SER75 |
| H | GLY76 |
| H | GLN77 |
| H | SER194 |
| H | THR196 |
| H | LYS197 |
| H | GLY207 |
| site_id | AD7 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 H 401 |
| Chain | Residue |
| H | ASN147 |
| H | LYS197 |
| H | VAL322 |
| H | SER323 |
| H | LEU324 |
| H | THR338 |
| H | ARG358 |
| H | HOH699 |
| H | HOH756 |
| H | HOH777 |
Functional Information from PROSITE/UniProt
| site_id | PS00211 |
| Number of Residues | 15 |
| Details | ABC_TRANSPORTER_1 ABC transporters family signature. FSSGQAAAATLLSLV |
| Chain | Residue | Details |
| A | PHE73-VAL87 |
