4U0T

Crystal structure of ADC-7 beta-lactamase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008800	molecular_function	beta-lactamase activity
A	0017001	biological_process	antibiotic catabolic process
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0046677	biological_process	response to antibiotic
B	0008800	molecular_function	beta-lactamase activity
B	0017001	biological_process	antibiotic catabolic process
B	0030288	cellular_component	outer membrane-bounded periplasmic space
B	0046677	biological_process	response to antibiotic
C	0008800	molecular_function	beta-lactamase activity
C	0017001	biological_process	antibiotic catabolic process
C	0030288	cellular_component	outer membrane-bounded periplasmic space
C	0046677	biological_process	response to antibiotic
D	0008800	molecular_function	beta-lactamase activity
D	0017001	biological_process	antibiotic catabolic process
D	0030288	cellular_component	outer membrane-bounded periplasmic space
D	0046677	biological_process	response to antibiotic
E	0008800	molecular_function	beta-lactamase activity
E	0017001	biological_process	antibiotic catabolic process
E	0030288	cellular_component	outer membrane-bounded periplasmic space
E	0046677	biological_process	response to antibiotic
F	0008800	molecular_function	beta-lactamase activity
F	0017001	biological_process	antibiotic catabolic process
F	0030288	cellular_component	outer membrane-bounded periplasmic space
F	0046677	biological_process	response to antibiotic
G	0008800	molecular_function	beta-lactamase activity
G	0017001	biological_process	antibiotic catabolic process
G	0030288	cellular_component	outer membrane-bounded periplasmic space
G	0046677	biological_process	response to antibiotic
H	0008800	molecular_function	beta-lactamase activity
H	0017001	biological_process	antibiotic catabolic process
H	0030288	cellular_component	outer membrane-bounded periplasmic space
H	0046677	biological_process	response to antibiotic

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue PO4 A 401

Chain	Residue
A	SER64
A	HOH729
A	HOH815
A	TYR150
A	LYS312
A	THR313
A	GLY314
A	HOH537
A	HOH538
A	HOH655
A	HOH698

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site_id	AC2
Number of Residues	10
Details	binding site for residue PO4 B 401

Chain	Residue
B	SER64
B	TYR150
B	LYS312
B	THR313
B	GLY314
B	HOH549
B	HOH620
B	HOH681
B	HOH742
B	HOH776

---

site_id	AC3
Number of Residues	10
Details	binding site for residue PO4 C 401

Chain	Residue
C	SER64
C	TYR150
C	LYS312
C	THR313
C	GLY314
C	HOH520
C	HOH521
C	HOH569
C	HOH604
C	HOH610

---

site_id	AC4
Number of Residues	7
Details	binding site for residue PO4 D 401

Chain	Residue
D	SER64
D	TYR150
D	LYS312
D	THR313
D	GLY314
D	HOH523
D	HOH530

---

site_id	AC5
Number of Residues	9
Details	binding site for residue PO4 E 401

Chain	Residue
E	SER64
E	TYR150
E	LYS312
E	THR313
E	GLY314
E	HOH521
E	HOH532
E	HOH610
E	HOH680

---

site_id	AC6
Number of Residues	9
Details	binding site for residue PO4 F 401

Chain	Residue
F	SER64
F	TYR150
F	LYS312
F	THR313
F	GLY314
F	HOH505
F	HOH538
F	HOH543
F	HOH555

---

site_id	AC7
Number of Residues	10
Details	binding site for residue PO4 G 401

Chain	Residue
G	SER64
G	TYR150
G	LYS312
G	THR313
G	GLY314
G	HOH509
G	HOH545
G	HOH550
G	HOH589
G	HOH621

---

site_id	AC8
Number of Residues	11
Details	binding site for residue PO4 H 401

Chain	Residue
H	SER64
H	TYR150
H	LYS312
H	THR313
H	GLY314
H	HOH513
H	HOH546
H	HOH553
H	HOH569
H	HOH581
H	HOH589

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Functional Information from PROSITE/UniProt

site_id	PS00336
Number of Residues	8
Details	BETA_LACTAMASE_C Beta-lactamase class-C active site. FELGSVSK

Chain	Residue	Details
A	PHE60-LYS67

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