4U0S
Structure of Eukaryotic fic domain containing protein with ADP
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 15 |
Details | binding site for residue ADP A 501 |
Chain | Residue |
A | HIS319 |
A | TYR399 |
A | TYR400 |
A | ASN407 |
A | MG502 |
A | HOH610 |
A | HOH612 |
A | VAL360 |
A | HIS363 |
A | ASP367 |
A | GLY368 |
A | ASN369 |
A | GLY370 |
A | ARG371 |
A | ARG374 |
site_id | AC2 |
Number of Residues | 3 |
Details | binding site for residue MG A 502 |
Chain | Residue |
A | ASP367 |
A | ADP501 |
A | HOH610 |
site_id | AC3 |
Number of Residues | 3 |
Details | binding site for residue PG4 A 503 |
Chain | Residue |
A | TYR357 |
A | LYS358 |
A | TYR361 |
site_id | AC4 |
Number of Residues | 16 |
Details | binding site for residue ADP B 501 |
Chain | Residue |
B | VAL316 |
B | HIS319 |
B | VAL360 |
B | HIS363 |
B | ASP367 |
B | GLY368 |
B | ASN369 |
B | GLY370 |
B | ARG371 |
B | TYR399 |
B | TYR400 |
B | LEU403 |
B | ASN407 |
B | MG502 |
B | HOH606 |
B | HOH608 |
site_id | AC5 |
Number of Residues | 4 |
Details | binding site for residue MG B 502 |
Chain | Residue |
B | ASP367 |
B | ADP501 |
B | HOH605 |
B | HOH606 |
site_id | AC6 |
Number of Residues | 2 |
Details | binding site for residue PG4 B 503 |
Chain | Residue |
B | TYR357 |
B | LYS358 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: ACT_SITE => ECO:0000269|PubMed:22266942 |
Chain | Residue | Details |
A | HIS363 | |
B | HIS363 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000269|PubMed:25435325, ECO:0007744|PDB:4U07, ECO:0007744|PDB:4U0U |
Chain | Residue | Details |
A | GLY234 | |
B | GLY234 |
site_id | SWS_FT_FI3 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000269|PubMed:25435325, ECO:0007744|PDB:4U07, ECO:0007744|PDB:4U0S, ECO:0007744|PDB:4U0U |
Chain | Residue | Details |
A | VAL316 | |
A | TYR399 | |
A | ASN407 | |
B | VAL316 | |
B | TYR399 | |
B | ASN407 |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000269|PubMed:25435325, ECO:0007744|PDB:4U07 |
Chain | Residue | Details |
A | ASP367 | |
B | ASP367 |
site_id | SWS_FT_FI5 |
Number of Residues | 2 |
Details | SITE: Important for autoinhibition of adenylyltransferase activity => ECO:0000269|PubMed:22266942, ECO:0000269|PubMed:25435325 |
Chain | Residue | Details |
A | GLY234 | |
B | GLY234 |
site_id | SWS_FT_FI6 |
Number of Residues | 2 |
Details | MOD_RES: O-AMP-threonine; by autocatalysis => ECO:0000305|PubMed:25601083 |
Chain | Residue | Details |
A | THR183 | |
B | THR183 |
site_id | SWS_FT_FI7 |
Number of Residues | 2 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498, ECO:0000269|PubMed:25601083 |
Chain | Residue | Details |
A | ASN275 | |
B | ASN275 |