4U0N

Structure of the Vibrio cholerae di-nucleotide cyclase (DncV) deletion mutant D-loop

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0140701	molecular_function	3',3'-cyclic GMP-AMP synthase activity
B	0140701	molecular_function	3',3'-cyclic GMP-AMP synthase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MG A 401

Chain	Residue
A	ASP131
A	ASP133
A	ASP193
A	HOH585
A	HOH588

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site_id	AC2
Number of Residues	12
Details	binding site for residue TLL A 402

Chain	Residue
A	PHE109
A	TRP110
A	ILE199
A	ASP205
A	ASP224
A	LYS226
A	HOH609
A	HOH684
A	LYS37
A	ARG40
A	THR106
A	ARG108

---

site_id	AC3
Number of Residues	4
Details	binding site for residue MG B 401

Chain	Residue
B	ASP131
B	ASP133
B	ASP193
B	HOH602

---

site_id	AC4
Number of Residues	12
Details	binding site for residue TLL B 402

Chain	Residue
B	LYS37
B	ARG40
B	LEU41
B	ARG108
B	PHE109
B	TRP110
B	ILE199
B	ASP205
B	SER206
B	ASP224
B	LYS226
B	HOH702

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	38
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25131990","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25201413","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25865248","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4U03","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4U0M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XJ3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XJ4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XJ5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25131990","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25201413","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25865248","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4TXY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4TXZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4TY0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4U03","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4U0N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XJ5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25131990","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25201413","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4U0M","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25131990","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25201413","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4U03","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XJ3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XJ4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XJ5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25131990","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25201413","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25865248","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4U03","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4U0M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XJ3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XJ5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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