4TX9
Crystal structure of HisAp from Streptomyces sviceus with degraded ProFAR
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000105 | biological_process | L-histidine biosynthetic process |
| A | 0000162 | biological_process | L-tryptophan biosynthetic process |
| A | 0003949 | molecular_function | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity |
| A | 0004640 | molecular_function | phosphoribosylanthranilate isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | ARG23 |
| A | HOH528 |
| A | HOH627 |
| A | HOH674 |
| A | ASP175 |
| A | GLY176 |
| A | GLY201 |
| A | GLY202 |
| A | GLY226 |
| A | LYS227 |
| A | HOH510 |
| A | HOH521 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | binding site for residue AMZ A 302 |
| Chain | Residue |
| A | GLY27 |
| A | VAL56 |
| A | LEU58 |
| A | PHE62 |
| A | SER85 |
| A | GLY86 |
| A | GLY87 |
| A | ARG89 |
| A | GLY108 |
| A | THR109 |
| A | ASP134 |
| A | GLY144 |
| A | TRP145 |
| A | HOH502 |
| A | HOH512 |
| A | HOH518 |
| A | HOH532 |
| A | HOH554 |
| A | HOH647 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | ASP194 |
| A | ARG195 |
| A | HOH566 |
