4TUF
Catalytic domain of the major endoglucanase from Xanthomonas campestris pv. campestris
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000272 | biological_process | polysaccharide catabolic process |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0000272 | biological_process | polysaccharide catabolic process |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0000272 | biological_process | polysaccharide catabolic process |
| C | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0000272 | biological_process | polysaccharide catabolic process |
| D | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| D | 0005975 | biological_process | carbohydrate metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue 2HP A 401 |
| Chain | Residue |
| A | LYS68 |
| A | ASP107 |
| A | LYS119 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue 2HP A 402 |
| Chain | Residue |
| A | SER27 |
| A | ASN254 |
| A | ARG255 |
| A | HOH522 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue 2HP A 403 |
| Chain | Residue |
| A | ASP160 |
| A | 2HP407 |
| A | HOH555 |
| B | CYS229 |
| A | ARG92 |
| A | GLN156 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue 2HP A 404 |
| Chain | Residue |
| A | GLY192 |
| A | ASN193 |
| A | ALA194 |
| A | ASP197 |
| A | LYS200 |
| A | HOH535 |
| A | HOH560 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue 2HP A 405 |
| Chain | Residue |
| A | PHE293 |
| A | THR296 |
| A | HIS297 |
| A | HOH539 |
| A | HOH502 |
| C | ASN166 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue 2HP A 406 |
| Chain | Residue |
| A | ASP139 |
| A | ALA141 |
| A | GLY142 |
| A | HOH529 |
| A | HOH541 |
| B | TRP237 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue 2HP A 407 |
| Chain | Residue |
| A | LEU91 |
| A | ARG92 |
| A | ASP160 |
| A | 2HP403 |
| B | CYS229 |
| B | CYS246 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue 2HP B 401 |
| Chain | Residue |
| B | ARG65 |
| B | ASN66 |
| B | ASP69 |
| D | ARG65 |
| D | ASN66 |
| D | ASP69 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue 2HP B 402 |
| Chain | Residue |
| B | LYS68 |
| B | ASP107 |
| B | HOH502 |
| D | 2HP404 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for residue 2HP B 403 |
| Chain | Residue |
| A | ARG162 |
| B | GLY190 |
| B | GLY192 |
| B | ASP197 |
| B | ASN199 |
| B | LYS200 |
| B | THR247 |
| B | 2HP408 |
| B | HOH538 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue 2HP B 404 |
| Chain | Residue |
| B | ASP101 |
| B | SER103 |
| B | ARG104 |
| B | HOH532 |
| D | 2HP401 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue 2HP B 405 |
| Chain | Residue |
| B | HIS136 |
| B | ILE143 |
| B | ASN181 |
| B | GLU182 |
| B | GLU303 |
| B | TRP337 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue 2HP B 406 |
| Chain | Residue |
| A | ILE143 |
| A | HIS184 |
| B | GLU145 |
| B | HIS184 |
| B | TRP237 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue 2HP B 407 |
| Chain | Residue |
| A | TRP237 |
| B | ASP139 |
| B | ALA141 |
| B | GLY142 |
| B | HOH521 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue 2HP B 408 |
| Chain | Residue |
| B | GLY192 |
| B | ALA194 |
| B | ASP197 |
| B | LYS200 |
| B | 2HP403 |
| B | HOH537 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue 2HP C 401 |
| Chain | Residue |
| C | GLY192 |
| C | ASN193 |
| C | ALA194 |
| C | ASP197 |
| C | LYS200 |
| C | HOH509 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue 2HP C 402 |
| Chain | Residue |
| C | LYS68 |
| C | ASP107 |
| C | LYS119 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue 2HP C 403 |
| Chain | Residue |
| C | HIS136 |
| C | ILE143 |
| C | ASN181 |
| C | GLU182 |
| C | GLU303 |
| C | TRP337 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue 2HP C 404 |
| Chain | Residue |
| C | GLU310 |
| C | ARG351 |
| C | ASP352 |
| C | ARG358 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue 2HP C 405 |
| Chain | Residue |
| A | CYS229 |
| C | LEU91 |
| C | ARG92 |
| C | ASP160 |
| C | PHE163 |
| site_id | AE3 |
| Number of Residues | 8 |
| Details | binding site for residue 2HP C 406 |
| Chain | Residue |
| C | ASP139 |
| C | GLY142 |
| C | SER144 |
| C | 2HP407 |
| C | 2HP408 |
| C | HOH504 |
| D | GLU145 |
| D | HIS184 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue 2HP C 407 |
| Chain | Residue |
| C | ASP139 |
| C | ALA141 |
| C | GLY142 |
| C | 2HP406 |
| C | HOH504 |
| D | TRP237 |
| site_id | AE5 |
| Number of Residues | 8 |
| Details | binding site for residue 2HP C 408 |
| Chain | Residue |
| C | ILE143 |
| C | GLU145 |
| C | HIS184 |
| C | TRP237 |
| C | 2HP406 |
| D | ILE143 |
| D | GLU145 |
| D | HIS184 |
| site_id | AE6 |
| Number of Residues | 3 |
| Details | binding site for residue 2HP D 401 |
| Chain | Residue |
| B | 2HP404 |
| D | LYS68 |
| D | ASP107 |
| site_id | AE7 |
| Number of Residues | 6 |
| Details | binding site for residue 2HP D 402 |
| Chain | Residue |
| D | HIS136 |
| D | ILE143 |
| D | ASN181 |
| D | GLU182 |
| D | GLU303 |
| D | TRP337 |
| site_id | AE8 |
| Number of Residues | 6 |
| Details | binding site for residue 2HP D 403 |
| Chain | Residue |
| D | GLY192 |
| D | ASN193 |
| D | ALA194 |
| D | ASP197 |
| D | LYS200 |
| D | HOH516 |
| site_id | AE9 |
| Number of Residues | 5 |
| Details | binding site for residue 2HP D 404 |
| Chain | Residue |
| B | LYS68 |
| B | 2HP402 |
| D | ASP101 |
| D | SER103 |
| D | ARG104 |
Functional Information from PROSITE/UniProt
| site_id | PS00659 |
| Number of Residues | 10 |
| Details | GLYCOSYL_HYDROL_F5 Glycosyl hydrolases family 5 signature. LGLDLKNEPH |
| Chain | Residue | Details |
| A | LEU175-HIS184 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
