4TTG
Beta-galactosidase (E. coli) in the presence of potassium chloride.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0004565 | molecular_function | beta-galactosidase activity |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0005990 | biological_process | lactose catabolic process |
| A | 0009341 | cellular_component | beta-galactosidase complex |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0030246 | molecular_function | carbohydrate binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0004565 | molecular_function | beta-galactosidase activity |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0005990 | biological_process | lactose catabolic process |
| B | 0009341 | cellular_component | beta-galactosidase complex |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0030246 | molecular_function | carbohydrate binding |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| C | 0004565 | molecular_function | beta-galactosidase activity |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0005990 | biological_process | lactose catabolic process |
| C | 0009341 | cellular_component | beta-galactosidase complex |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| C | 0030246 | molecular_function | carbohydrate binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| D | 0004565 | molecular_function | beta-galactosidase activity |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0005990 | biological_process | lactose catabolic process |
| D | 0009341 | cellular_component | beta-galactosidase complex |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| D | 0030246 | molecular_function | carbohydrate binding |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 3001 |
| Chain | Residue |
| A | GLU416 |
| A | HIS418 |
| A | GLU461 |
| A | HOH3223 |
| A | HOH3287 |
| A | HOH3365 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 3002 |
| Chain | Residue |
| A | GLN163 |
| A | ASP193 |
| A | ASP15 |
| A | ASN18 |
| A | VAL21 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 3003 |
| Chain | Residue |
| A | GLN718 |
| A | HOH3474 |
| A | HOH3585 |
| A | HOH3644 |
| A | HOH3811 |
| A | HOH3867 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 3004 |
| Chain | Residue |
| A | DMS3015 |
| A | HOH3112 |
| A | HOH3133 |
| A | HOH3205 |
| D | HOH1213 |
| D | HOH1231 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue K A 3005 |
| Chain | Residue |
| A | TYR100 |
| A | ASP201 |
| A | PHE601 |
| A | ASN604 |
| A | HOH3379 |
| A | HOH3484 |
| A | HOH3907 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue K A 3006 |
| Chain | Residue |
| A | PHE556 |
| A | TYR559 |
| A | PRO560 |
| A | LEU562 |
| A | HOH3607 |
| A | HOH3814 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue K A 3007 |
| Chain | Residue |
| A | PHE931 |
| A | PRO932 |
| A | LEU967 |
| A | MET968 |
| A | THR970 |
| A | HOH3738 |
| A | HOH3891 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue K A 3008 |
| Chain | Residue |
| A | LEU910 |
| A | THR911 |
| A | ALA913 |
| A | HOH3490 |
| A | HOH3733 |
| A | HOH3811 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 3009 |
| Chain | Residue |
| A | ARG37 |
| A | ASN38 |
| A | GLN50 |
| A | HOH3202 |
| A | HOH3879 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 3010 |
| Chain | Residue |
| A | THR229 |
| A | VAL330 |
| A | GLY331 |
| A | ASN449 |
| A | PRO451 |
| A | HOH3220 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 3011 |
| Chain | Residue |
| A | ARG557 |
| A | HIS622 |
| A | GLN628 |
| A | HOH3413 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 3012 |
| Chain | Residue |
| A | LYS380 |
| A | ASN383 |
| A | PHE626 |
| A | TYR642 |
| A | TRP708 |
| A | HOH3422 |
| site_id | AD4 |
| Number of Residues | 10 |
| Details | binding site for residue DMS A 3013 |
| Chain | Residue |
| A | PRO32 |
| A | PHE33 |
| A | ALA34 |
| A | TRP36 |
| A | ASP45 |
| A | ALA327 |
| A | DMS3029 |
| A | HOH3619 |
| A | HOH3630 |
| A | HOH3823 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 3014 |
| Chain | Residue |
| A | THR271 |
| A | LEU291 |
| A | ARG292 |
| A | HOH3869 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 3015 |
| Chain | Residue |
| A | HIS316 |
| A | GLY320 |
| A | MG3004 |
| A | HOH3133 |
| D | SER132 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 3016 |
| Chain | Residue |
| A | GLU508 |
| A | PRO1001 |
| A | VAL1003 |
| A | HOH3246 |
| A | HOH3687 |
| A | HOH4179 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 3017 |
| Chain | Residue |
| A | HOH3892 |
| A | LEU54 |
| A | ASN55 |
| A | PHE127 |
| A | HOH3884 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 3018 |
| Chain | Residue |
| A | GLU334 |
| A | VAL335 |
| A | PRO480 |
| A | HOH3417 |
| A | HOH3420 |
| A | HOH3711 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 3019 |
| Chain | Residue |
| A | PRO106 |
| A | PRO115 |
| A | HOH3572 |
| A | HOH3815 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 3020 |
| Chain | Residue |
| A | ILE576 |
| A | PRO584 |
| A | SER586 |
| A | ARG973 |
| A | HOH3311 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 3021 |
| Chain | Residue |
| A | GLY275 |
| A | GLU277 |
| A | VAL289 |
| A | THR290 |
| A | HOH3781 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 3022 |
| Chain | Residue |
| A | GLY593 |
| A | ASP594 |
| A | THR595 |
| A | HOH4224 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 3023 |
| Chain | Residue |
| A | VAL84 |
| A | VAL85 |
| A | HIS93 |
| A | HOH3654 |
| A | HOH4062 |
| site_id | AE6 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 3024 |
| Chain | Residue |
| A | ARG251 |
| A | ASP252 |
| A | HOH3119 |
| A | HOH3853 |
| D | ARG251 |
| site_id | AE7 |
| Number of Residues | 7 |
| Details | binding site for residue DMS A 3025 |
| Chain | Residue |
| A | ASP428 |
| A | PRO430 |
| A | HOH4195 |
| D | TRP474 |
| D | VAL478 |
| D | HOH1820 |
| D | HOH2069 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 3026 |
| Chain | Residue |
| A | HIS93 |
| A | GLY94 |
| A | TYR95 |
| A | HOH3812 |
| site_id | AE9 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 3027 |
| Chain | Residue |
| A | TYR926 |
| A | TYR962 |
| A | ARG973 |
| A | LEU976 |
| site_id | AF1 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 3028 |
| Chain | Residue |
| A | TRP695 |
| A | GLN719 |
| A | ARG721 |
| A | HOH3490 |
| A | HOH3644 |
| A | HOH3733 |
| site_id | AF2 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 3029 |
| Chain | Residue |
| A | ASP45 |
| A | ARG46 |
| A | PRO47 |
| A | DMS3013 |
| A | HOH3699 |
| A | HOH3932 |
| site_id | AF3 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 3030 |
| Chain | Residue |
| A | GLU57 |
| A | LEU125 |
| A | THR126 |
| A | HOH3723 |
| B | GLU819 |
| site_id | AF4 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 3031 |
| Chain | Residue |
| A | PHE629 |
| A | TRP720 |
| A | HOH3445 |
| site_id | AF5 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 3032 |
| Chain | Residue |
| A | SER132 |
| A | TRP133 |
| A | GLU136 |
| A | HIS216 |
| site_id | AF6 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 3033 |
| Chain | Residue |
| A | ARG404 |
| A | TYR405 |
| A | HOH3151 |
| C | ASP772 |
| site_id | AF7 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 3034 |
| Chain | Residue |
| A | THR706 |
| A | ALA707 |
| A | SER709 |
| site_id | AF8 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 3035 |
| Chain | Residue |
| A | ARG230 |
| A | PHE231 |
| A | ASN232 |
| A | ALA238 |
| A | VAL239 |
| site_id | AF9 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 3036 |
| Chain | Residue |
| A | PRO47 |
| A | SER48 |
| A | GLN49 |
| A | LEU51 |
| site_id | AG1 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 3037 |
| Chain | Residue |
| A | GLU744 |
| A | MET745 |
| A | ARG760 |
| A | GLN761 |
| site_id | AG2 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 3038 |
| Chain | Residue |
| A | ASN102 |
| A | ASP598 |
| A | PHE601 |
| A | HOH4109 |
| site_id | AG3 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 3039 |
| Chain | Residue |
| A | ASP252 |
| A | ARG255 |
| A | HOH3124 |
| site_id | AG4 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 3040 |
| Chain | Residue |
| A | ALA61 |
| A | TRP62 |
| A | GLU80 |
| A | ASP82 |
| A | HOH3780 |
| site_id | AG5 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 3041 |
| Chain | Residue |
| A | LEU397 |
| A | THR400 |
| A | LEU401 |
| A | ARG404 |
| A | HOH4177 |
| site_id | AG6 |
| Number of Residues | 2 |
| Details | binding site for residue DMS B 1101 |
| Chain | Residue |
| A | VAL728 |
| B | GLN843 |
| site_id | AG7 |
| Number of Residues | 2 |
| Details | binding site for residue DMS B 1102 |
| Chain | Residue |
| B | LYS811 |
| B | HIS844 |
| site_id | AG8 |
| Number of Residues | 2 |
| Details | binding site for residue DMS B 1103 |
| Chain | Residue |
| B | ASP507 |
| B | GLU508 |
| site_id | AG9 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 1104 |
| Chain | Residue |
| B | GLU416 |
| B | HIS418 |
| B | GLU461 |
| B | HOH1298 |
| B | HOH1362 |
| B | HOH1438 |
| site_id | AH1 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 1105 |
| Chain | Residue |
| B | ASP15 |
| B | ASN18 |
| B | VAL21 |
| B | GLN163 |
| B | ASP193 |
| site_id | AH2 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 1106 |
| Chain | Residue |
| B | GLN718 |
| B | HOH1547 |
| B | HOH1662 |
| B | HOH1723 |
| B | HOH1907 |
| B | HOH1966 |
| site_id | AH3 |
| Number of Residues | 7 |
| Details | binding site for residue K B 1107 |
| Chain | Residue |
| B | TYR100 |
| B | ASP201 |
| B | PHE601 |
| B | ASN604 |
| B | HOH1452 |
| B | HOH1557 |
| B | HOH2020 |
| site_id | AH4 |
| Number of Residues | 6 |
| Details | binding site for residue K B 1108 |
| Chain | Residue |
| B | PHE556 |
| B | TYR559 |
| B | PRO560 |
| B | LEU562 |
| B | HOH1684 |
| B | HOH2102 |
| site_id | AH5 |
| Number of Residues | 7 |
| Details | binding site for residue K B 1109 |
| Chain | Residue |
| B | PHE931 |
| B | PRO932 |
| B | LEU967 |
| B | MET968 |
| B | THR970 |
| B | HOH1827 |
| B | HOH1998 |
| site_id | AH6 |
| Number of Residues | 6 |
| Details | binding site for residue K B 1110 |
| Chain | Residue |
| B | LEU910 |
| B | THR911 |
| B | ALA913 |
| B | HOH1563 |
| B | HOH1821 |
| B | HOH1907 |
| site_id | AH7 |
| Number of Residues | 7 |
| Details | binding site for residue DMS B 1111 |
| Chain | Residue |
| B | THR229 |
| B | VAL330 |
| B | GLY331 |
| B | ASN449 |
| B | PRO451 |
| B | ARG482 |
| B | HOH1295 |
| site_id | AH8 |
| Number of Residues | 4 |
| Details | binding site for residue DMS B 1112 |
| Chain | Residue |
| B | ARG557 |
| B | HIS622 |
| B | GLN628 |
| B | HOH1486 |
| site_id | AH9 |
| Number of Residues | 6 |
| Details | binding site for residue DMS B 1113 |
| Chain | Residue |
| B | LYS380 |
| B | ASN383 |
| B | PHE626 |
| B | TYR642 |
| B | TRP708 |
| B | HOH1495 |
| site_id | AI1 |
| Number of Residues | 8 |
| Details | binding site for residue DMS B 1114 |
| Chain | Residue |
| B | PHE33 |
| B | ALA34 |
| B | TRP36 |
| B | ASP45 |
| B | ALA327 |
| B | HOH1697 |
| B | HOH1709 |
| B | HOH1919 |
| site_id | AI2 |
| Number of Residues | 4 |
| Details | binding site for residue DMS B 1115 |
| Chain | Residue |
| B | THR271 |
| B | LEU291 |
| B | ARG292 |
| B | HOH1969 |
| site_id | AI3 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 1116 |
| Chain | Residue |
| B | GLU508 |
| B | PRO1001 |
| B | VAL1003 |
| B | HOH1321 |
| B | HOH1770 |
| site_id | AI4 |
| Number of Residues | 3 |
| Details | binding site for residue DMS B 1117 |
| Chain | Residue |
| B | LEU54 |
| B | ASN55 |
| B | HOH1901 |
| site_id | AI5 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 1118 |
| Chain | Residue |
| B | GLU334 |
| B | VAL335 |
| B | PRO480 |
| B | HOH1493 |
| B | HOH1795 |
| site_id | AI6 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 1119 |
| Chain | Residue |
| B | ILE576 |
| B | TRP585 |
| B | SER586 |
| B | ARG973 |
| B | HOH1386 |
| site_id | AI7 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 1120 |
| Chain | Residue |
| B | GLY275 |
| B | VAL289 |
| B | THR290 |
| B | ARG292 |
| B | HOH2116 |
| site_id | AI8 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 1121 |
| Chain | Residue |
| B | GLY593 |
| B | ASP594 |
| B | THR595 |
| B | HOH1632 |
| B | HOH2013 |
| site_id | AI9 |
| Number of Residues | 3 |
| Details | binding site for residue DMS B 1122 |
| Chain | Residue |
| B | VAL84 |
| B | VAL85 |
| B | HIS93 |
| site_id | AJ1 |
| Number of Residues | 3 |
| Details | binding site for residue DMS B 1123 |
| Chain | Residue |
| B | LYS621 |
| B | TRP717 |
| B | HOH1618 |
| site_id | AJ2 |
| Number of Residues | 3 |
| Details | binding site for residue DMS B 1124 |
| Chain | Residue |
| B | LEU250 |
| B | ARG251 |
| B | ASP252 |
| site_id | AJ3 |
| Number of Residues | 6 |
| Details | binding site for residue DMS B 1125 |
| Chain | Residue |
| B | PHE231 |
| B | ASN232 |
| B | PHE235 |
| B | GLU334 |
| B | ARG336 |
| B | HOH1904 |
| site_id | AJ4 |
| Number of Residues | 3 |
| Details | binding site for residue DMS B 1126 |
| Chain | Residue |
| B | HIS93 |
| B | GLY94 |
| B | TYR95 |
| site_id | AJ5 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 1127 |
| Chain | Residue |
| B | TYR926 |
| B | TYR962 |
| B | ARG973 |
| B | LEU976 |
| B | HOH2240 |
| site_id | AJ6 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 1128 |
| Chain | Residue |
| B | GLN719 |
| B | ARG721 |
| B | HOH1563 |
| B | HOH1723 |
| B | HOH1821 |
| site_id | AJ7 |
| Number of Residues | 4 |
| Details | binding site for residue DMS B 1129 |
| Chain | Residue |
| B | GLU57 |
| B | LEU125 |
| B | THR126 |
| B | HOH1809 |
| site_id | AJ8 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 1130 |
| Chain | Residue |
| B | PHE629 |
| B | ARG630 |
| B | GLN718 |
| B | TRP720 |
| B | HOH1518 |
| site_id | AJ9 |
| Number of Residues | 6 |
| Details | binding site for residue DMS B 1131 |
| Chain | Residue |
| B | ARG37 |
| B | SER132 |
| B | TRP133 |
| B | HIS216 |
| B | HOH1218 |
| B | HOH1228 |
| site_id | AK1 |
| Number of Residues | 4 |
| Details | binding site for residue DMS B 1132 |
| Chain | Residue |
| B | ASN102 |
| B | ASP598 |
| B | PHE601 |
| B | HOH2122 |
| site_id | AK2 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 1133 |
| Chain | Residue |
| B | VAL267 |
| B | ASN294 |
| B | VAL295 |
| B | GLU296 |
| B | HOH1851 |
| site_id | AK3 |
| Number of Residues | 3 |
| Details | binding site for residue DMS B 1134 |
| Chain | Residue |
| B | PRO306 |
| B | ASN307 |
| B | HOH2135 |
| site_id | AK4 |
| Number of Residues | 2 |
| Details | binding site for residue DMS B 1135 |
| Chain | Residue |
| B | TYR405 |
| B | HOH2097 |
| site_id | AK5 |
| Number of Residues | 3 |
| Details | binding site for residue DMS B 1136 |
| Chain | Residue |
| B | ARG230 |
| B | ASN232 |
| B | VAL239 |
| site_id | AK6 |
| Number of Residues | 2 |
| Details | binding site for residue DMS B 1137 |
| Chain | Residue |
| B | PRO106 |
| B | PRO596 |
| site_id | AK7 |
| Number of Residues | 3 |
| Details | binding site for residue DMS B 1138 |
| Chain | Residue |
| B | LEU250 |
| B | HOH2175 |
| C | ARG425 |
| site_id | AK8 |
| Number of Residues | 3 |
| Details | binding site for residue DMS B 1139 |
| Chain | Residue |
| B | THR706 |
| B | ALA707 |
| B | SER709 |
| site_id | AK9 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 1140 |
| Chain | Residue |
| B | TYR472 |
| B | THR494 |
| B | THR496 |
| B | ASP497 |
| B | HOH1936 |
| site_id | AL1 |
| Number of Residues | 2 |
| Details | binding site for residue DMS B 1141 |
| Chain | Residue |
| B | PRO348 |
| B | HOH1274 |
| site_id | AL2 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 1142 |
| Chain | Residue |
| B | ALA61 |
| B | TRP62 |
| B | GLU80 |
| B | ASP82 |
| B | HOH1874 |
| site_id | AL3 |
| Number of Residues | 2 |
| Details | binding site for residue DMS B 1143 |
| Chain | Residue |
| B | SER1010 |
| B | ALA1011 |
| site_id | AL4 |
| Number of Residues | 3 |
| Details | binding site for residue DMS B 1144 |
| Chain | Residue |
| B | ARG721 |
| B | LEU722 |
| B | ALA723 |
| site_id | AL5 |
| Number of Residues | 6 |
| Details | binding site for residue MG C 3001 |
| Chain | Residue |
| C | GLU416 |
| C | HIS418 |
| C | GLU461 |
| C | HOH3197 |
| C | HOH3261 |
| C | HOH3338 |
| site_id | AL6 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 3002 |
| Chain | Residue |
| C | ASP15 |
| C | ASN18 |
| C | VAL21 |
| C | GLN163 |
| C | ASP193 |
| site_id | AL7 |
| Number of Residues | 6 |
| Details | binding site for residue MG C 3003 |
| Chain | Residue |
| B | HOH1228 |
| B | HOH1248 |
| B | HOH1267 |
| C | HOH3105 |
| C | HOH3134 |
| C | HOH3147 |
| site_id | AL8 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 3004 |
| Chain | Residue |
| A | HOH3120 |
| A | HOH3132 |
| C | HOH3124 |
| C | HOH3151 |
| C | HOH3155 |
| site_id | AL9 |
| Number of Residues | 7 |
| Details | binding site for residue K C 3005 |
| Chain | Residue |
| C | TYR100 |
| C | ASP201 |
| C | PHE601 |
| C | ASN604 |
| C | HOH3352 |
| C | HOH3457 |
| C | HOH4132 |
| site_id | AM1 |
| Number of Residues | 6 |
| Details | binding site for residue K C 3006 |
| Chain | Residue |
| C | PHE556 |
| C | TYR559 |
| C | PRO560 |
| C | LEU562 |
| C | HOH3585 |
| C | HOH3806 |
| site_id | AM2 |
| Number of Residues | 6 |
| Details | binding site for residue K C 3007 |
| Chain | Residue |
| C | PHE931 |
| C | PRO932 |
| C | LEU967 |
| C | MET968 |
| C | THR970 |
| C | HOH3896 |
| site_id | AM3 |
| Number of Residues | 6 |
| Details | binding site for residue K C 3008 |
| Chain | Residue |
| C | LEU910 |
| C | THR911 |
| C | ALA913 |
| C | HOH3463 |
| C | HOH3717 |
| C | HOH3803 |
| site_id | AM4 |
| Number of Residues | 7 |
| Details | binding site for residue DMS C 3009 |
| Chain | Residue |
| C | THR229 |
| C | VAL330 |
| C | GLY331 |
| C | ASN449 |
| C | PRO451 |
| C | ARG482 |
| C | HOH3194 |
| site_id | AM5 |
| Number of Residues | 4 |
| Details | binding site for residue DMS C 3010 |
| Chain | Residue |
| C | ARG557 |
| C | HIS622 |
| C | GLN628 |
| C | HOH3386 |
| site_id | AM6 |
| Number of Residues | 6 |
| Details | binding site for residue DMS C 3011 |
| Chain | Residue |
| C | LYS380 |
| C | ASN383 |
| C | PHE626 |
| C | TYR642 |
| C | TRP708 |
| C | HOH3395 |
| site_id | AM7 |
| Number of Residues | 8 |
| Details | binding site for residue DMS C 3012 |
| Chain | Residue |
| C | PRO32 |
| C | PHE33 |
| C | ALA34 |
| C | TRP36 |
| C | ASP45 |
| C | ALA327 |
| C | HOH3598 |
| C | HOH3817 |
| site_id | AM8 |
| Number of Residues | 4 |
| Details | binding site for residue DMS C 3013 |
| Chain | Residue |
| C | THR271 |
| C | LEU291 |
| C | ARG292 |
| C | HOH3868 |
| site_id | AM9 |
| Number of Residues | 5 |
| Details | binding site for residue DMS C 3014 |
| Chain | Residue |
| C | GLU508 |
| C | PRO1001 |
| C | VAL1003 |
| C | HOH3220 |
| C | HOH3668 |
| site_id | AN1 |
| Number of Residues | 3 |
| Details | binding site for residue DMS C 3015 |
| Chain | Residue |
| C | LEU54 |
| C | ASN55 |
| C | HOH3142 |
| site_id | AN2 |
| Number of Residues | 5 |
| Details | binding site for residue DMS C 3016 |
| Chain | Residue |
| C | GLU334 |
| C | VAL335 |
| C | PRO480 |
| C | HOH3393 |
| C | HOH3692 |
| site_id | AN3 |
| Number of Residues | 4 |
| Details | binding site for residue DMS C 3017 |
| Chain | Residue |
| C | PRO106 |
| C | PRO115 |
| C | HOH3549 |
| C | HOH3808 |
| site_id | AN4 |
| Number of Residues | 5 |
| Details | binding site for residue DMS C 3018 |
| Chain | Residue |
| C | ILE576 |
| C | PRO584 |
| C | SER586 |
| C | ARG973 |
| C | HOH3285 |
| site_id | AN5 |
| Number of Residues | 4 |
| Details | binding site for residue DMS C 3019 |
| Chain | Residue |
| C | GLY275 |
| C | VAL289 |
| C | THR290 |
| C | HOH4013 |
| site_id | AN6 |
| Number of Residues | 5 |
| Details | binding site for residue DMS C 3020 |
| Chain | Residue |
| C | GLY593 |
| C | ASP594 |
| C | THR595 |
| C | HOH3532 |
| C | HOH3908 |
| site_id | AN7 |
| Number of Residues | 3 |
| Details | binding site for residue DMS C 3021 |
| Chain | Residue |
| C | VAL84 |
| C | VAL85 |
| C | HIS93 |
| site_id | AN8 |
| Number of Residues | 4 |
| Details | binding site for residue DMS C 3022 |
| Chain | Residue |
| C | LYS621 |
| C | TRP717 |
| C | HOH3518 |
| C | HOH4156 |
| site_id | AN9 |
| Number of Residues | 3 |
| Details | binding site for residue DMS C 3023 |
| Chain | Residue |
| C | ARG251 |
| C | ASP252 |
| C | HOH3849 |
| site_id | AO1 |
| Number of Residues | 5 |
| Details | binding site for residue DMS C 3024 |
| Chain | Residue |
| C | PHE231 |
| C | ASN232 |
| C | PHE235 |
| C | GLU334 |
| C | HOH3800 |
| site_id | AO2 |
| Number of Residues | 5 |
| Details | binding site for residue DMS C 3025 |
| Chain | Residue |
| B | VAL478 |
| B | HOH1794 |
| C | ASP428 |
| C | PRO430 |
| C | HOH3175 |
| site_id | AO3 |
| Number of Residues | 3 |
| Details | binding site for residue DMS C 3026 |
| Chain | Residue |
| C | HIS93 |
| C | GLY94 |
| C | TYR95 |
| site_id | AO4 |
| Number of Residues | 4 |
| Details | binding site for residue DMS C 3027 |
| Chain | Residue |
| C | TYR926 |
| C | TYR962 |
| C | ARG973 |
| C | HOH4188 |
| site_id | AO5 |
| Number of Residues | 6 |
| Details | binding site for residue DMS C 3028 |
| Chain | Residue |
| C | GLN719 |
| C | ARG721 |
| C | HOH3394 |
| C | HOH3463 |
| C | HOH3625 |
| C | HOH3717 |
| site_id | AO6 |
| Number of Residues | 4 |
| Details | binding site for residue DMS C 3029 |
| Chain | Residue |
| C | ASP45 |
| C | PRO47 |
| C | HOH3111 |
| C | HOH3946 |
| site_id | AO7 |
| Number of Residues | 5 |
| Details | binding site for residue DMS C 3030 |
| Chain | Residue |
| C | PHE629 |
| C | ARG630 |
| C | GLN718 |
| C | TRP720 |
| C | HOH3418 |
| site_id | AO8 |
| Number of Residues | 4 |
| Details | binding site for residue DMS C 3031 |
| Chain | Residue |
| C | GLN50 |
| C | SER132 |
| C | TRP133 |
| C | HIS216 |
| site_id | AO9 |
| Number of Residues | 3 |
| Details | binding site for residue DMS C 3032 |
| Chain | Residue |
| C | PRO306 |
| C | ASN307 |
| C | HOH4030 |
| site_id | AP1 |
| Number of Residues | 4 |
| Details | binding site for residue DMS C 3033 |
| Chain | Residue |
| C | GLN381 |
| C | ALA707 |
| C | SER709 |
| C | GLU710 |
| site_id | AP2 |
| Number of Residues | 4 |
| Details | binding site for residue DMS C 3034 |
| Chain | Residue |
| C | ASN102 |
| C | ASP598 |
| C | PHE601 |
| C | HOH4019 |
| site_id | AP3 |
| Number of Residues | 2 |
| Details | binding site for residue DMS C 3035 |
| Chain | Residue |
| C | ARG230 |
| C | PHE231 |
| site_id | AP4 |
| Number of Residues | 5 |
| Details | binding site for residue DMS C 3036 |
| Chain | Residue |
| C | TYR472 |
| C | THR494 |
| C | THR496 |
| C | ASP497 |
| C | HOH3832 |
| site_id | AP5 |
| Number of Residues | 4 |
| Details | binding site for residue DMS C 3037 |
| Chain | Residue |
| B | GLN49 |
| C | SER48 |
| C | GLN49 |
| C | LEU51 |
| site_id | AP6 |
| Number of Residues | 4 |
| Details | binding site for residue DMS C 3038 |
| Chain | Residue |
| C | GLN266 |
| C | ALA268 |
| D | LEU740 |
| D | THR742 |
| site_id | AP7 |
| Number of Residues | 3 |
| Details | binding site for residue DMS C 3039 |
| Chain | Residue |
| C | TRP585 |
| C | HIS972 |
| C | HOH3656 |
| site_id | AP8 |
| Number of Residues | 1 |
| Details | binding site for residue DMS C 3040 |
| Chain | Residue |
| C | ASN55 |
| site_id | AP9 |
| Number of Residues | 6 |
| Details | binding site for residue DMS C 3041 |
| Chain | Residue |
| C | ALA61 |
| C | TRP62 |
| C | GLU80 |
| C | ASP82 |
| C | HOH3753 |
| C | HOH3772 |
| site_id | AQ1 |
| Number of Residues | 1 |
| Details | binding site for residue DMS C 3042 |
| Chain | Residue |
| C | ASN345 |
| site_id | AQ2 |
| Number of Residues | 3 |
| Details | binding site for residue DMS C 3043 |
| Chain | Residue |
| C | TRP62 |
| C | TYR95 |
| C | ASP96 |
| site_id | AQ3 |
| Number of Residues | 5 |
| Details | binding site for residue DMS C 3044 |
| Chain | Residue |
| C | GLU314 |
| C | HIS316 |
| C | GLY320 |
| C | THR321 |
| C | HOH4167 |
| site_id | AQ4 |
| Number of Residues | 3 |
| Details | binding site for residue DMS C 3045 |
| Chain | Residue |
| B | ARG425 |
| C | ASP287 |
| C | HOH3171 |
| site_id | AQ5 |
| Number of Residues | 5 |
| Details | binding site for residue DMS D 1101 |
| Chain | Residue |
| D | ASN102 |
| D | ASP598 |
| D | PHE601 |
| D | HOH1946 |
| D | HOH2237 |
| site_id | AQ6 |
| Number of Residues | 6 |
| Details | binding site for residue MG D 1102 |
| Chain | Residue |
| D | GLU416 |
| D | HIS418 |
| D | GLU461 |
| D | HOH1333 |
| D | HOH1397 |
| D | HOH1473 |
| site_id | AQ7 |
| Number of Residues | 5 |
| Details | binding site for residue MG D 1103 |
| Chain | Residue |
| D | ASP15 |
| D | ASN18 |
| D | VAL21 |
| D | GLN163 |
| D | ASP193 |
| site_id | AQ8 |
| Number of Residues | 6 |
| Details | binding site for residue MG D 1104 |
| Chain | Residue |
| A | HOH3143 |
| A | HOH3160 |
| A | HOH3201 |
| D | HOH1208 |
| D | HOH1223 |
| D | HOH1225 |
| site_id | AQ9 |
| Number of Residues | 7 |
| Details | binding site for residue K D 1105 |
| Chain | Residue |
| D | TYR100 |
| D | ASP201 |
| D | PHE601 |
| D | ASN604 |
| D | HOH1486 |
| D | HOH1589 |
| D | HOH2030 |
| site_id | AR1 |
| Number of Residues | 6 |
| Details | binding site for residue K D 1106 |
| Chain | Residue |
| D | PHE556 |
| D | TYR559 |
| D | PRO560 |
| D | LEU562 |
| D | HOH1715 |
| D | HOH1931 |
| site_id | AR2 |
| Number of Residues | 6 |
| Details | binding site for residue K D 1107 |
| Chain | Residue |
| D | PHE931 |
| D | PRO932 |
| D | LEU967 |
| D | MET968 |
| D | THR970 |
| D | HOH2011 |
| site_id | AR3 |
| Number of Residues | 6 |
| Details | binding site for residue K D 1108 |
| Chain | Residue |
| D | LEU910 |
| D | THR911 |
| D | ALA913 |
| D | HOH1595 |
| D | HOH1846 |
| D | HOH1928 |
| site_id | AR4 |
| Number of Residues | 7 |
| Details | binding site for residue DMS D 1109 |
| Chain | Residue |
| D | THR229 |
| D | VAL330 |
| D | GLY331 |
| D | ASN449 |
| D | PRO451 |
| D | ARG482 |
| D | HOH1330 |
| site_id | AR5 |
| Number of Residues | 5 |
| Details | binding site for residue DMS D 1110 |
| Chain | Residue |
| D | ARG557 |
| D | HIS622 |
| D | GLN623 |
| D | GLN628 |
| D | HOH1519 |
| site_id | AR6 |
| Number of Residues | 6 |
| Details | binding site for residue DMS D 1111 |
| Chain | Residue |
| D | LYS380 |
| D | ASN383 |
| D | PHE626 |
| D | TYR642 |
| D | TRP708 |
| D | HOH1528 |
| site_id | AR7 |
| Number of Residues | 10 |
| Details | binding site for residue DMS D 1112 |
| Chain | Residue |
| D | PRO32 |
| D | PHE33 |
| D | ALA34 |
| D | TRP36 |
| D | ASP45 |
| D | ALA327 |
| D | DMS1125 |
| D | HOH1728 |
| D | HOH1739 |
| D | HOH1940 |
| site_id | AR8 |
| Number of Residues | 4 |
| Details | binding site for residue DMS D 1113 |
| Chain | Residue |
| D | THR271 |
| D | LEU291 |
| D | ARG292 |
| D | HOH1986 |
| site_id | AR9 |
| Number of Residues | 6 |
| Details | binding site for residue DMS D 1114 |
| Chain | Residue |
| A | GLU136 |
| D | GLU314 |
| D | HIS316 |
| D | GLY320 |
| D | DMS1127 |
| D | HOH1202 |
| site_id | AS1 |
| Number of Residues | 5 |
| Details | binding site for residue DMS D 1115 |
| Chain | Residue |
| D | GLU508 |
| D | PRO1001 |
| D | VAL1003 |
| D | HOH1356 |
| D | HOH1795 |
| site_id | AS2 |
| Number of Residues | 3 |
| Details | binding site for residue DMS D 1116 |
| Chain | Residue |
| D | LEU54 |
| D | ASN55 |
| D | HOH2012 |
| site_id | AS3 |
| Number of Residues | 4 |
| Details | binding site for residue DMS D 1117 |
| Chain | Residue |
| D | VAL335 |
| D | PRO480 |
| D | HOH1526 |
| D | HOH1821 |
| site_id | AS4 |
| Number of Residues | 4 |
| Details | binding site for residue DMS D 1118 |
| Chain | Residue |
| D | PRO106 |
| D | PRO115 |
| D | HOH1679 |
| D | HOH1933 |
| site_id | AS5 |
| Number of Residues | 5 |
| Details | binding site for residue DMS D 1119 |
| Chain | Residue |
| D | ILE576 |
| D | PRO584 |
| D | SER586 |
| D | ARG973 |
| D | HOH1421 |
| site_id | AS6 |
| Number of Residues | 4 |
| Details | binding site for residue DMS D 1120 |
| Chain | Residue |
| D | GLY275 |
| D | THR290 |
| D | ARG292 |
| D | HOH2257 |
| site_id | AS7 |
| Number of Residues | 4 |
| Details | binding site for residue DMS D 1121 |
| Chain | Residue |
| D | GLY593 |
| D | ASP594 |
| D | THR595 |
| D | HOH2022 |
| site_id | AS8 |
| Number of Residues | 2 |
| Details | binding site for residue DMS D 1122 |
| Chain | Residue |
| D | ARG251 |
| D | ASP252 |
| site_id | AS9 |
| Number of Residues | 4 |
| Details | binding site for residue DMS D 1123 |
| Chain | Residue |
| D | HIS93 |
| D | GLY94 |
| D | TYR95 |
| D | HOH1929 |
| site_id | AT1 |
| Number of Residues | 4 |
| Details | binding site for residue DMS D 1124 |
| Chain | Residue |
| D | GLN719 |
| D | ARG721 |
| D | HOH1595 |
| D | HOH2272 |
| site_id | AT2 |
| Number of Residues | 7 |
| Details | binding site for residue DMS D 1125 |
| Chain | Residue |
| D | TRP36 |
| D | ASP45 |
| D | ARG46 |
| D | PRO47 |
| D | DMS1112 |
| D | HOH1808 |
| D | HOH2058 |
| site_id | AT3 |
| Number of Residues | 5 |
| Details | binding site for residue DMS D 1126 |
| Chain | Residue |
| D | PHE629 |
| D | ARG630 |
| D | GLN718 |
| D | TRP720 |
| D | HOH1550 |
| site_id | AT4 |
| Number of Residues | 7 |
| Details | binding site for residue DMS D 1127 |
| Chain | Residue |
| A | PRO218 |
| A | ILE323 |
| A | HOH3117 |
| D | GLY320 |
| D | LEU322 |
| D | DMS1114 |
| D | HOH1201 |
| site_id | AT5 |
| Number of Residues | 6 |
| Details | binding site for residue DMS D 1128 |
| Chain | Residue |
| D | GLN49 |
| D | GLN50 |
| D | ASP130 |
| D | SER132 |
| D | TRP133 |
| D | HOH1203 |
| site_id | AT6 |
| Number of Residues | 6 |
| Details | binding site for residue DMS D 1129 |
| Chain | Residue |
| D | TRP133 |
| D | LEU134 |
| D | GLU136 |
| D | GLY137 |
| D | SER174 |
| D | HOH2311 |
| site_id | AT7 |
| Number of Residues | 4 |
| Details | binding site for residue DMS D 1130 |
| Chain | Residue |
| D | THR706 |
| D | ALA707 |
| D | SER709 |
| D | GLU710 |
| site_id | AT8 |
| Number of Residues | 4 |
| Details | binding site for residue DMS D 1132 |
| Chain | Residue |
| D | VAL84 |
| D | VAL85 |
| D | HIS93 |
| D | HOH2023 |
| site_id | AT9 |
| Number of Residues | 3 |
| Details | binding site for residue DMS D 1133 |
| Chain | Residue |
| D | TYR926 |
| D | TYR962 |
| D | ARG973 |
Functional Information from PROSITE/UniProt
| site_id | PS00608 |
| Number of Residues | 15 |
| Details | GLYCOSYL_HYDROL_F2_2 Glycosyl hydrolases family 2 acid/base catalyst. DRNHPSVIIWSlg.NE |
| Chain | Residue | Details |
| A | ASP447-GLU461 |
| site_id | PS00719 |
| Number of Residues | 26 |
| Details | GLYCOSYL_HYDROL_F2_1 Glycosyl hydrolases family 2 signature 1. NaVRCSHYPnhplWYtlcDryGLYVV |
| Chain | Residue | Details |
| A | ASN385-VAL410 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_01687","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"HAMAP-Rule","id":"MF_01687","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 48 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01687","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"source":"HAMAP-Rule","id":"MF_01687","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
