4TR1
Crystal structure of GSH-bound cGrx2/C15S
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0015038 | molecular_function | glutathione disulfide oxidoreductase activity |
| A | 0034599 | biological_process | cellular response to oxidative stress |
| A | 0045454 | biological_process | cell redox homeostasis |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0015038 | molecular_function | glutathione disulfide oxidoreductase activity |
| B | 0034599 | biological_process | cellular response to oxidative stress |
| B | 0045454 | biological_process | cell redox homeostasis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue GSH A 101 |
| Chain | Residue |
| A | LYS9 |
| A | CSO66 |
| A | ASP67 |
| A | HOH219 |
| A | HOH221 |
| A | HOH228 |
| A | HOH251 |
| A | HOH292 |
| A | TYR11 |
| A | TYR11 |
| A | CYS12 |
| A | TYR14 |
| A | THR52 |
| A | VAL53 |
| A | PRO54 |
| A | GLY65 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue GSH B 101 |
| Chain | Residue |
| B | LYS9 |
| B | TYR11 |
| B | CYS12 |
| B | THR52 |
| B | VAL53 |
| B | PRO54 |
| B | GLU61 |
| B | GLY65 |
| B | CSU66 |
| B | ASP67 |
| B | LYS81 |
| B | HOH209 |
| B | HOH234 |
| B | HOH250 |
| B | HOH286 |
