4TQT
Crystal structure of Dihydropyrimidinase from Brucella suis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004157 | molecular_function | dihydropyrimidinase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004157 | molecular_function | dihydropyrimidinase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004157 | molecular_function | dihydropyrimidinase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0004157 | molecular_function | dihydropyrimidinase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0004157 | molecular_function | dihydropyrimidinase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0004157 | molecular_function | dihydropyrimidinase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| F | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 501 |
| Chain | Residue |
| A | HIS61 |
| A | HIS63 |
| A | KCX151 |
| A | ASP317 |
| A | ZN502 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 502 |
| Chain | Residue |
| A | HOH606 |
| A | KCX151 |
| A | HIS184 |
| A | HIS240 |
| A | ZN501 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | ASP300 |
| A | ARG359 |
| A | EDO507 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | GLN312 |
| A | ASN372 |
| A | LYS375 |
| A | HOH765 |
| B | HOH839 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | ASN148 |
| A | GLY178 |
| A | ILE376 |
| A | ASN459 |
| A | GLY460 |
| A | ASN463 |
| A | HOH689 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | GLY257 |
| A | ARG259 |
| B | GLY358 |
| B | ARG359 |
| B | EDO502 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 507 |
| Chain | Residue |
| A | GLY358 |
| A | ARG359 |
| A | EDO503 |
| B | GLY257 |
| B | ARG259 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue ZN B 500 |
| Chain | Residue |
| B | HIS61 |
| B | HIS63 |
| B | KCX151 |
| B | ASP317 |
| B | ZN501 |
| B | HOH611 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue ZN B 501 |
| Chain | Residue |
| B | KCX151 |
| B | HIS184 |
| B | HIS240 |
| B | ZN500 |
| B | HOH611 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 502 |
| Chain | Residue |
| A | EDO506 |
| B | ASP300 |
| B | ARG359 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 503 |
| Chain | Residue |
| B | GLN312 |
| B | ASN372 |
| B | LYS375 |
| site_id | AD3 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 504 |
| Chain | Residue |
| B | ASN148 |
| B | GLY178 |
| B | ILE376 |
| B | ASN459 |
| B | GLY460 |
| B | ASN463 |
| B | HOH712 |
| B | HOH725 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue ZN C 500 |
| Chain | Residue |
| C | HIS61 |
| C | HIS63 |
| C | KCX151 |
| C | ASP317 |
| C | ZN501 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue ZN C 501 |
| Chain | Residue |
| C | KCX151 |
| C | HIS184 |
| C | HIS240 |
| C | ZN500 |
| C | HOH602 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 502 |
| Chain | Residue |
| C | ASP300 |
| C | ARG359 |
| D | TRP469 |
| D | EDO505 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 503 |
| Chain | Residue |
| C | GLN312 |
| C | ASN372 |
| C | LYS375 |
| C | HOH666 |
| C | HOH762 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 504 |
| Chain | Residue |
| C | ASN148 |
| C | GLY178 |
| C | ILE376 |
| C | ASN459 |
| C | GLY460 |
| C | ASN463 |
| C | HOH738 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 505 |
| Chain | Residue |
| C | GLY257 |
| C | ARG259 |
| D | GLY358 |
| D | ARG359 |
| D | EDO502 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue ZN D 500 |
| Chain | Residue |
| D | HIS61 |
| D | HIS63 |
| D | KCX151 |
| D | ASP317 |
| D | ZN501 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue ZN D 501 |
| Chain | Residue |
| D | ZN500 |
| D | HOH609 |
| D | KCX151 |
| D | HIS184 |
| D | HIS240 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 502 |
| Chain | Residue |
| C | EDO505 |
| D | ASP300 |
| D | ARG359 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 503 |
| Chain | Residue |
| D | GLN312 |
| D | ASN372 |
| D | LYS375 |
| D | HOH789 |
| site_id | AE5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO D 504 |
| Chain | Residue |
| D | ASN148 |
| D | GLY178 |
| D | ILE376 |
| D | ASN378 |
| D | ASN459 |
| D | GLY460 |
| D | ASN463 |
| D | HOH669 |
| site_id | AE6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 505 |
| Chain | Residue |
| C | GLY358 |
| C | ARG359 |
| C | EDO502 |
| D | GLY257 |
| D | ARG259 |
| site_id | AE7 |
| Number of Residues | 5 |
| Details | binding site for residue ZN E 500 |
| Chain | Residue |
| E | HIS61 |
| E | HIS63 |
| E | KCX151 |
| E | ASP317 |
| E | ZN501 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue ZN E 501 |
| Chain | Residue |
| E | KCX151 |
| E | HIS184 |
| E | HIS240 |
| E | ZN500 |
| site_id | AE9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO E 502 |
| Chain | Residue |
| E | ASP300 |
| E | ARG359 |
| F | EDO505 |
| site_id | AF1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO E 503 |
| Chain | Residue |
| E | GLN312 |
| E | ASN372 |
| E | LYS375 |
| site_id | AF2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO E 504 |
| Chain | Residue |
| E | ASN148 |
| E | GLY178 |
| E | ILE376 |
| E | ASN378 |
| E | ASN459 |
| E | GLY460 |
| E | ASN463 |
| E | HOH724 |
| site_id | AF3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO E 505 |
| Chain | Residue |
| E | GLY257 |
| E | ARG259 |
| F | GLY358 |
| F | ARG359 |
| F | EDO502 |
| site_id | AF4 |
| Number of Residues | 5 |
| Details | binding site for residue ZN F 500 |
| Chain | Residue |
| F | HIS61 |
| F | HIS63 |
| F | KCX151 |
| F | ASP317 |
| F | ZN501 |
| site_id | AF5 |
| Number of Residues | 5 |
| Details | binding site for residue ZN F 501 |
| Chain | Residue |
| F | KCX151 |
| F | HIS184 |
| F | HIS240 |
| F | ZN500 |
| F | HOH627 |
| site_id | AF6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO F 502 |
| Chain | Residue |
| E | EDO505 |
| F | ASP300 |
| F | ARG359 |
| site_id | AF7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO F 503 |
| Chain | Residue |
| F | GLN312 |
| F | ASN372 |
| F | LYS375 |
| F | HOH756 |
| site_id | AF8 |
| Number of Residues | 8 |
| Details | binding site for residue EDO F 504 |
| Chain | Residue |
| F | ASN148 |
| F | GLY178 |
| F | ILE376 |
| F | ASN378 |
| F | ASN459 |
| F | GLY460 |
| F | ASN463 |
| F | HOH650 |
| site_id | AF9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO F 505 |
| Chain | Residue |
| E | GLY358 |
| E | ARG359 |
| E | EDO502 |
| F | GLY257 |
| F | ARG259 |
