4TQO
The crystal structure of methanol dehydrogenase from Methylococcus capsulatus (Bath)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0016020 | cellular_component | membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| A | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0016020 | cellular_component | membrane |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| B | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| C | 0005509 | molecular_function | calcium ion binding |
| C | 0016020 | cellular_component | membrane |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| C | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| D | 0005509 | molecular_function | calcium ion binding |
| D | 0016020 | cellular_component | membrane |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| D | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| E | 0005509 | molecular_function | calcium ion binding |
| E | 0016020 | cellular_component | membrane |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| E | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| F | 0005509 | molecular_function | calcium ion binding |
| F | 0016020 | cellular_component | membrane |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| F | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| G | 0005509 | molecular_function | calcium ion binding |
| G | 0016020 | cellular_component | membrane |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| G | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| H | 0005509 | molecular_function | calcium ion binding |
| H | 0016020 | cellular_component | membrane |
| H | 0016491 | molecular_function | oxidoreductase activity |
| H | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| H | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| I | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| I | 0015946 | biological_process | methanol oxidation |
| I | 0052933 | molecular_function | alcohol dehydrogenase (cytochrome c(L)) activity |
| J | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| J | 0015946 | biological_process | methanol oxidation |
| J | 0052933 | molecular_function | alcohol dehydrogenase (cytochrome c(L)) activity |
| K | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| K | 0015946 | biological_process | methanol oxidation |
| K | 0052933 | molecular_function | alcohol dehydrogenase (cytochrome c(L)) activity |
| L | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| L | 0015946 | biological_process | methanol oxidation |
| L | 0052933 | molecular_function | alcohol dehydrogenase (cytochrome c(L)) activity |
| M | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| M | 0015946 | biological_process | methanol oxidation |
| M | 0052933 | molecular_function | alcohol dehydrogenase (cytochrome c(L)) activity |
| N | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| N | 0015946 | biological_process | methanol oxidation |
| N | 0052933 | molecular_function | alcohol dehydrogenase (cytochrome c(L)) activity |
| O | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| O | 0015946 | biological_process | methanol oxidation |
| O | 0052933 | molecular_function | alcohol dehydrogenase (cytochrome c(L)) activity |
| P | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| P | 0015946 | biological_process | methanol oxidation |
| P | 0052933 | molecular_function | alcohol dehydrogenase (cytochrome c(L)) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue CA B 701 |
| Chain | Residue |
| B | GLU205 |
| B | ASN289 |
| B | ASP331 |
| B | PQQ702 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | binding site for residue PQQ B 702 |
| Chain | Residue |
| B | GLY203 |
| B | ALA204 |
| B | GLU205 |
| B | THR269 |
| B | TRP271 |
| B | ASN289 |
| B | ASP331 |
| B | ARG358 |
| B | ASN421 |
| B | TRP497 |
| B | GLY560 |
| B | TRP561 |
| B | CA701 |
| B | HOH981 |
| B | HOH1034 |
| B | GLU83 |
| B | VAL135 |
| B | ARG137 |
| B | THR187 |
| B | ALA202 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CA A 701 |
| Chain | Residue |
| A | GLU205 |
| A | ASN289 |
| A | ASP331 |
| A | PQQ702 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | binding site for residue PQQ A 702 |
| Chain | Residue |
| A | GLU83 |
| A | CYS132 |
| A | ARG137 |
| A | THR187 |
| A | ALA202 |
| A | GLY203 |
| A | ALA204 |
| A | GLU205 |
| A | THR269 |
| A | TRP271 |
| A | ASN289 |
| A | ASP331 |
| A | ARG358 |
| A | ASN421 |
| A | TRP497 |
| A | GLY560 |
| A | TRP561 |
| A | CA701 |
| A | HOH832 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue CA C 701 |
| Chain | Residue |
| C | GLU205 |
| C | ASN289 |
| C | ASP331 |
| C | PQQ702 |
| site_id | AC6 |
| Number of Residues | 19 |
| Details | binding site for residue PQQ C 702 |
| Chain | Residue |
| C | GLU83 |
| C | VAL135 |
| C | ARG137 |
| C | THR187 |
| C | ALA202 |
| C | GLY203 |
| C | ALA204 |
| C | GLU205 |
| C | THR269 |
| C | TRP271 |
| C | ASN289 |
| C | ASP331 |
| C | ARG358 |
| C | ASN421 |
| C | TRP497 |
| C | GLY560 |
| C | TRP561 |
| C | CA701 |
| C | HOH879 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue CA D 701 |
| Chain | Residue |
| D | GLU205 |
| D | ASN289 |
| D | ASP331 |
| D | PQQ702 |
| site_id | AC8 |
| Number of Residues | 18 |
| Details | binding site for residue PQQ D 702 |
| Chain | Residue |
| D | GLU83 |
| D | VAL135 |
| D | ARG137 |
| D | THR187 |
| D | ALA202 |
| D | GLY203 |
| D | ALA204 |
| D | GLU205 |
| D | THR269 |
| D | TRP271 |
| D | ASP331 |
| D | ARG358 |
| D | ASN421 |
| D | TRP497 |
| D | GLY560 |
| D | TRP561 |
| D | CA701 |
| D | HOH849 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue CA E 701 |
| Chain | Residue |
| E | GLU205 |
| E | ASN289 |
| E | ASP331 |
| E | PQQ702 |
| site_id | AD1 |
| Number of Residues | 18 |
| Details | binding site for residue PQQ E 702 |
| Chain | Residue |
| E | THR187 |
| E | ALA202 |
| E | GLY203 |
| E | ALA204 |
| E | GLU205 |
| E | THR269 |
| E | TRP271 |
| E | ASN289 |
| E | ASP331 |
| E | ARG358 |
| E | TRP497 |
| E | GLY560 |
| E | TRP561 |
| E | CA701 |
| E | HOH929 |
| E | GLU83 |
| E | VAL135 |
| E | ARG137 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue CA F 701 |
| Chain | Residue |
| F | GLU205 |
| F | ASN289 |
| F | ASP331 |
| F | PQQ702 |
| site_id | AD3 |
| Number of Residues | 20 |
| Details | binding site for residue PQQ F 702 |
| Chain | Residue |
| F | GLU83 |
| F | VAL135 |
| F | ARG137 |
| F | THR187 |
| F | ALA202 |
| F | GLY203 |
| F | ALA204 |
| F | GLU205 |
| F | THR269 |
| F | TRP271 |
| F | ASN289 |
| F | ASP331 |
| F | ARG358 |
| F | ASN421 |
| F | TRP497 |
| F | GLY560 |
| F | TRP561 |
| F | CA701 |
| F | HOH868 |
| F | HOH919 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue CA G 701 |
| Chain | Residue |
| G | GLU205 |
| G | ASN289 |
| G | ASP331 |
| G | PQQ702 |
| site_id | AD5 |
| Number of Residues | 19 |
| Details | binding site for residue PQQ G 702 |
| Chain | Residue |
| G | GLU83 |
| G | CYS132 |
| G | VAL135 |
| G | ARG137 |
| G | THR187 |
| G | ALA202 |
| G | GLY203 |
| G | ALA204 |
| G | GLU205 |
| G | THR269 |
| G | TRP271 |
| G | ASN289 |
| G | ASP331 |
| G | ARG358 |
| G | ASN421 |
| G | TRP497 |
| G | GLY560 |
| G | TRP561 |
| G | CA701 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue CA H 701 |
| Chain | Residue |
| H | GLU205 |
| H | ASN289 |
| H | ASP331 |
| H | PQQ702 |
| site_id | AD7 |
| Number of Residues | 19 |
| Details | binding site for residue PQQ H 702 |
| Chain | Residue |
| H | GLU83 |
| H | VAL135 |
| H | ARG137 |
| H | THR187 |
| H | ALA202 |
| H | GLY203 |
| H | ALA204 |
| H | GLU205 |
| H | THR269 |
| H | TRP271 |
| H | ASN289 |
| H | ASP331 |
| H | ARG358 |
| H | ASN421 |
| H | TRP497 |
| H | GLY560 |
| H | TRP561 |
| H | CA701 |
| H | HOH878 |
Functional Information from PROSITE/UniProt
| site_id | PS00364 |
| Number of Residues | 22 |
| Details | BACTERIAL_PQQ_2 Bacterial quinoprotein dehydrogenases signature 2. WgwyaYDpklDMIYYgsGnpAP |
| Chain | Residue | Details |
| B | TRP271-PRO292 |
