4TQ1

Crystal structure of human ATG5-TECAIR

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000045	biological_process	autophagosome assembly
A	0000423	biological_process	mitophagy
A	0002376	biological_process	immune system process
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005776	cellular_component	autophagosome
A	0005829	cellular_component	cytosol
A	0005930	cellular_component	axoneme
A	0006914	biological_process	autophagy
A	0006915	biological_process	apoptotic process
A	0006995	biological_process	cellular response to nitrogen starvation
A	0010040	biological_process	response to iron(II) ion
A	0010508	biological_process	positive regulation of autophagy
A	0016020	cellular_component	membrane
A	0016236	biological_process	macroautophagy
A	0019776	molecular_function	Atg8-family ligase activity
A	0030424	cellular_component	axon
A	0030670	cellular_component	phagocytic vesicle membrane
A	0032480	biological_process	negative regulation of type I interferon production
A	0032991	cellular_component	protein-containing complex
A	0034045	cellular_component	phagophore assembly site membrane
A	0034274	cellular_component	Atg12-Atg5-Atg16 complex
A	0034727	biological_process	piecemeal microautophagy of the nucleus
A	0035973	biological_process	aggrephagy
A	0043066	biological_process	negative regulation of apoptotic process
A	0043069	biological_process	negative regulation of programmed cell death
A	0043687	biological_process	post-translational protein modification
A	0044233	cellular_component	mitochondria-associated endoplasmic reticulum membrane contact site
A	0045202	cellular_component	synapse
A	0045824	biological_process	negative regulation of innate immune response
A	0050687	biological_process	negative regulation of defense response to virus
A	0061684	biological_process	chaperone-mediated autophagy
A	0061908	cellular_component	phagophore
A	0062029	biological_process	positive regulation of stress granule assembly
A	0071500	biological_process	cellular response to nitrosative stress
A	0098685	cellular_component	Schaffer collateral - CA1 synapse
A	0098794	cellular_component	postsynapse
A	0098930	biological_process	axonal transport
A	0098978	cellular_component	glutamatergic synapse
A	0099072	biological_process	regulation of postsynaptic membrane neurotransmitter receptor levels
A	0099170	biological_process	postsynaptic modulation of chemical synaptic transmission
A	1901096	biological_process	regulation of autophagosome maturation
A	1902017	biological_process	regulation of cilium assembly
A	1902617	biological_process	response to fluoride
A	1904093	biological_process	negative regulation of autophagic cell death
A	1904973	biological_process	positive regulation of viral translation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ATG12)","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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