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4TN1

Translation initiation factor eIF5B (517-858) mutant D533R from C. thermophilum, bound to GTPgammaS

Functional Information from GO Data
ChainGOidnamespacecontents
A0003924molecular_functionGTPase activity
A0005525molecular_functionGTP binding
B0003924molecular_functionGTPase activity
B0005525molecular_functionGTP binding
Functional Information from PDB Data
site_idAC1
Number of Residues20
Detailsbinding site for residue GSP B 901
ChainResidue
BVAL532
BGLY597
BASN648
BLYS649
BASP651
BARG652
BSER716
BALA717
BHIS718
BMG902
BHOH1029
BARG533
BHOH1030
BTHR534
BGLY535
BLYS536
BTHR537
BLYS538
BGLN549
BTHR557

site_idAC2
Number of Residues5
Detailsbinding site for residue MG B 902
ChainResidue
BTHR537
BTHR557
BGSP901
BHOH1029
BHOH1030

site_idAC3
Number of Residues20
Detailsbinding site for residue GSP A 901
ChainResidue
AVAL532
AARG533
ATHR534
AGLY535
ALYS536
ATHR537
ALYS538
AGLN549
ATHR557
AGLY597
AASN648
ALYS649
AASP651
AARG652
ASER716
AALA717
AHIS718
AMG902
AHOH1015
AHOH1016

site_idAC4
Number of Residues5
Detailsbinding site for residue MG A 902
ChainResidue
ATHR537
ATHR557
AGSP901
AHOH1015
AHOH1016

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:25225612, ECO:0007744|PDB:4TMV, ECO:0007744|PDB:4TMW, ECO:0007744|PDB:4TMX
ChainResidueDetails
BARG533
BGLY555
AARG533
AGLY555

site_idSWS_FT_FI2
Number of Residues6
DetailsBINDING: BINDING => ECO:0000269|PubMed:25225612
ChainResidueDetails
BTHR537
BGLN549
BTHR557
ATHR537
AGLN549
ATHR557

site_idSWS_FT_FI3
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:24686316, ECO:0000269|PubMed:25225612
ChainResidueDetails
BASN648
BALA717
AASN648
AALA717

226707

PDB entries from 2024-10-30

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