4TM4
Kutzneria sp. 744 ornithine N-hydroxylase, KtzI-FADox-red-NADP+-Br
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0006879 | biological_process | intracellular iron ion homeostasis |
| A | 0044249 | biological_process | cellular biosynthetic process |
| A | 0047091 | molecular_function | L-lysine 6-monooxygenase (NADPH) activity |
| A | 1901566 | biological_process | organonitrogen compound biosynthetic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0006879 | biological_process | intracellular iron ion homeostasis |
| B | 0044249 | biological_process | cellular biosynthetic process |
| B | 0047091 | molecular_function | L-lysine 6-monooxygenase (NADPH) activity |
| B | 1901566 | biological_process | organonitrogen compound biosynthetic process |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004497 | molecular_function | monooxygenase activity |
| C | 0006879 | biological_process | intracellular iron ion homeostasis |
| C | 0044249 | biological_process | cellular biosynthetic process |
| C | 0047091 | molecular_function | L-lysine 6-monooxygenase (NADPH) activity |
| C | 1901566 | biological_process | organonitrogen compound biosynthetic process |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004497 | molecular_function | monooxygenase activity |
| D | 0006879 | biological_process | intracellular iron ion homeostasis |
| D | 0044249 | biological_process | cellular biosynthetic process |
| D | 0047091 | molecular_function | L-lysine 6-monooxygenase (NADPH) activity |
| D | 1901566 | biological_process | organonitrogen compound biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | binding site for residue FDA A 501 |
| Chain | Residue |
| A | GLY18 |
| A | MET54 |
| A | MET61 |
| A | GLN62 |
| A | ARG104 |
| A | SER126 |
| A | GLU127 |
| A | VAL128 |
| A | SER163 |
| A | THR164 |
| A | GLY165 |
| A | GLY20 |
| A | LEU166 |
| A | TYR346 |
| A | SER403 |
| A | LEU404 |
| A | LEU405 |
| A | NAP502 |
| A | HOH602 |
| A | HOH662 |
| A | PRO21 |
| A | ALA22 |
| A | PHE42 |
| A | GLU43 |
| A | ARG44 |
| A | TRP50 |
| A | HIS51 |
| site_id | AC2 |
| Number of Residues | 26 |
| Details | binding site for residue NAP A 502 |
| Chain | Residue |
| A | LYS60 |
| A | GLN62 |
| A | ARG104 |
| A | PRO171 |
| A | GLY205 |
| A | GLY206 |
| A | GLY207 |
| A | GLN208 |
| A | SER209 |
| A | GLU212 |
| A | ILE229 |
| A | PRO231 |
| A | ASN275 |
| A | SER277 |
| A | HIS309 |
| A | VAL310 |
| A | ALA343 |
| A | THR344 |
| A | GLY345 |
| A | FDA501 |
| A | HOH624 |
| A | HOH626 |
| A | HOH628 |
| A | HOH629 |
| A | HOH632 |
| D | TYR270 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue BR A 503 |
| Chain | Residue |
| A | ALA58 |
| A | PHE216 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue BR A 504 |
| Chain | Residue |
| A | SER64 |
| A | LYS67 |
| B | HIS98 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue BR A 506 |
| Chain | Residue |
| A | ARG374 |
| A | TYR376 |
| A | ASN407 |
| A | THR410 |
| A | GLU414 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue BR A 507 |
| Chain | Residue |
| A | GLY89 |
| A | LEU91 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue BR A 508 |
| Chain | Residue |
| A | ARG153 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue BR A 509 |
| Chain | Residue |
| A | HIS182 |
| A | HIS189 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | binding site for residue BR A 510 |
| Chain | Residue |
| A | PHE179 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue BR A 511 |
| Chain | Residue |
| A | TYR333 |
| B | ARG385 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue BR A 512 |
| Chain | Residue |
| A | ARG272 |
| site_id | AD3 |
| Number of Residues | 29 |
| Details | binding site for residue FDA B 501 |
| Chain | Residue |
| B | HOH667 |
| B | HOH668 |
| B | GLY18 |
| B | GLY20 |
| B | PRO21 |
| B | ALA22 |
| B | PHE42 |
| B | GLU43 |
| B | ARG44 |
| B | TRP50 |
| B | HIS51 |
| B | MET54 |
| B | MET61 |
| B | GLN62 |
| B | SER126 |
| B | VAL128 |
| B | SER163 |
| B | THR164 |
| B | GLY165 |
| B | LEU166 |
| B | TYR346 |
| B | SER403 |
| B | LEU404 |
| B | LEU405 |
| B | NAP502 |
| B | HOH603 |
| B | HOH604 |
| B | HOH613 |
| B | HOH636 |
| site_id | AD4 |
| Number of Residues | 27 |
| Details | binding site for residue NAP B 502 |
| Chain | Residue |
| B | LYS60 |
| B | GLN62 |
| B | ARG104 |
| B | PRO171 |
| B | GLY205 |
| B | GLY206 |
| B | GLY207 |
| B | GLN208 |
| B | SER209 |
| B | GLU212 |
| B | ILE229 |
| B | PRO231 |
| B | ASN275 |
| B | SER277 |
| B | HIS309 |
| B | VAL310 |
| B | ALA343 |
| B | THR344 |
| B | GLY345 |
| B | TYR346 |
| B | FDA501 |
| B | HOH608 |
| B | HOH609 |
| B | HOH628 |
| B | HOH647 |
| B | HOH666 |
| C | TYR270 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue BR B 503 |
| Chain | Residue |
| A | HIS98 |
| B | SER64 |
| B | ASN245 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue BR B 504 |
| Chain | Residue |
| B | PRO57 |
| B | ALA58 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue BR B 506 |
| Chain | Residue |
| B | GLY89 |
| B | LEU91 |
| B | VAL92 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue BR B 507 |
| Chain | Residue |
| B | HIS182 |
| B | HIS189 |
| site_id | AD9 |
| Number of Residues | 1 |
| Details | binding site for residue BR B 508 |
| Chain | Residue |
| C | LEU307 |
| site_id | AE1 |
| Number of Residues | 27 |
| Details | binding site for residue FDA C 501 |
| Chain | Residue |
| C | GLY18 |
| C | GLY20 |
| C | PRO21 |
| C | ALA22 |
| C | PHE42 |
| C | GLU43 |
| C | ARG44 |
| C | TRP50 |
| C | HIS51 |
| C | MET54 |
| C | MET61 |
| C | GLN62 |
| C | SER126 |
| C | VAL128 |
| C | SER163 |
| C | THR164 |
| C | GLY165 |
| C | LEU166 |
| C | TYR346 |
| C | SER403 |
| C | LEU404 |
| C | LEU405 |
| C | NAP502 |
| C | HOH608 |
| C | HOH609 |
| C | HOH615 |
| C | HOH625 |
| site_id | AE2 |
| Number of Residues | 27 |
| Details | binding site for residue NAP C 502 |
| Chain | Residue |
| B | TYR270 |
| C | LYS60 |
| C | GLN62 |
| C | ARG104 |
| C | PRO171 |
| C | GLY205 |
| C | GLY206 |
| C | GLY207 |
| C | GLN208 |
| C | SER209 |
| C | GLU212 |
| C | PRO231 |
| C | ASN275 |
| C | SER277 |
| C | HIS309 |
| C | VAL310 |
| C | ALA343 |
| C | THR344 |
| C | GLY345 |
| C | TYR346 |
| C | FDA501 |
| C | HOH604 |
| C | HOH605 |
| C | HOH606 |
| C | HOH629 |
| C | HOH653 |
| C | HOH655 |
| site_id | AE3 |
| Number of Residues | 2 |
| Details | binding site for residue BR C 503 |
| Chain | Residue |
| C | PRO57 |
| C | ALA58 |
| site_id | AE4 |
| Number of Residues | 3 |
| Details | binding site for residue BR C 504 |
| Chain | Residue |
| C | SER64 |
| C | LYS67 |
| D | HIS98 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue BR C 506 |
| Chain | Residue |
| C | ARG374 |
| C | TYR376 |
| C | ASN407 |
| C | THR410 |
| site_id | AE6 |
| Number of Residues | 2 |
| Details | binding site for residue BR C 507 |
| Chain | Residue |
| C | GLY89 |
| C | LEU91 |
| site_id | AE7 |
| Number of Residues | 2 |
| Details | binding site for residue BR C 508 |
| Chain | Residue |
| C | HIS182 |
| C | HIS189 |
| site_id | AE8 |
| Number of Residues | 2 |
| Details | binding site for residue BR C 509 |
| Chain | Residue |
| C | SER332 |
| D | ALA317 |
| site_id | AE9 |
| Number of Residues | 1 |
| Details | binding site for residue BR C 510 |
| Chain | Residue |
| C | TYR333 |
| site_id | AF1 |
| Number of Residues | 26 |
| Details | binding site for residue FDA D 501 |
| Chain | Residue |
| D | GLY18 |
| D | GLY20 |
| D | PRO21 |
| D | ALA22 |
| D | PHE42 |
| D | GLU43 |
| D | ARG44 |
| D | TRP50 |
| D | HIS51 |
| D | MET54 |
| D | MET61 |
| D | GLN62 |
| D | ARG104 |
| D | VAL128 |
| D | SER163 |
| D | THR164 |
| D | GLY165 |
| D | LEU166 |
| D | TYR346 |
| D | SER403 |
| D | LEU404 |
| D | LEU405 |
| D | NAP502 |
| D | HOH603 |
| D | HOH604 |
| D | HOH663 |
| site_id | AF2 |
| Number of Residues | 28 |
| Details | binding site for residue NAP D 502 |
| Chain | Residue |
| A | TYR270 |
| D | LYS60 |
| D | GLN62 |
| D | ARG104 |
| D | PRO171 |
| D | ALA204 |
| D | GLY205 |
| D | GLY206 |
| D | GLY207 |
| D | GLN208 |
| D | SER209 |
| D | GLU212 |
| D | ILE229 |
| D | PRO231 |
| D | ASN275 |
| D | SER277 |
| D | HIS309 |
| D | VAL310 |
| D | ALA343 |
| D | THR344 |
| D | GLY345 |
| D | TYR346 |
| D | FDA501 |
| D | HOH611 |
| D | HOH626 |
| D | HOH627 |
| D | HOH629 |
| D | HOH630 |
| site_id | AF3 |
| Number of Residues | 3 |
| Details | binding site for residue BR D 503 |
| Chain | Residue |
| D | GLY89 |
| D | LEU91 |
| D | VAL92 |
| site_id | AF4 |
| Number of Residues | 4 |
| Details | binding site for residue BR D 504 |
| Chain | Residue |
| C | HIS98 |
| D | SER64 |
| D | LYS67 |
| D | ASN245 |
| site_id | AF5 |
| Number of Residues | 3 |
| Details | binding site for residue BR D 506 |
| Chain | Residue |
| D | PRO57 |
| D | ALA58 |
| D | PHE216 |
| site_id | AF6 |
| Number of Residues | 4 |
| Details | binding site for residue BR D 507 |
| Chain | Residue |
| D | TRP181 |
| D | HIS182 |
| D | ARG185 |
| D | HIS189 |
| site_id | AF7 |
| Number of Residues | 1 |
| Details | binding site for residue BR D 508 |
| Chain | Residue |
| D | LEU307 |
| site_id | AF8 |
| Number of Residues | 2 |
| Details | binding site for residue BR D 509 |
| Chain | Residue |
| A | LEU307 |
| D | ASP255 |
