4TLW
CARDS TOXIN, FULL-LENGTH
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003950 | molecular_function | NAD+ poly-ADP-ribosyltransferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0008289 | molecular_function | lipid binding |
| A | 0009986 | cellular_component | cell surface |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0033099 | cellular_component | attachment organelle |
| A | 0044075 | biological_process | symbiont-mediated perturbation of host vacuole organization |
| A | 0044164 | cellular_component | host cell cytosol |
| A | 0044165 | cellular_component | host cell endoplasmic reticulum |
| A | 0090729 | molecular_function | toxin activity |
| A | 0141079 | biological_process | symbiont-mediated activation of host inflammasome-mediated signal transduction |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 166 |
| Details | Region: {"description":"D2 domain","evidences":[{"source":"PubMed","id":"25848012","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 151 |
| Details | Region: {"description":"D3 domain","evidences":[{"source":"PubMed","id":"25848012","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Motif: {"description":"KELED motif, involved in host ER trafficking, solvent exposed in the crystal structure","evidences":[{"source":"PubMed","id":"29362229","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4TLV","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"4TLW","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
