4TLV
CARDS TOXIN, NICKED
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003950 | molecular_function | NAD+ ADP-ribosyltransferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0008289 | molecular_function | lipid binding |
| A | 0009986 | cellular_component | cell surface |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0030430 | cellular_component | host cell cytoplasm |
| A | 0033099 | cellular_component | attachment organelle |
| A | 0042995 | cellular_component | cell projection |
| A | 0044075 | biological_process | symbiont-mediated perturbation of host vacuole organization |
| A | 0044164 | cellular_component | host cell cytosol |
| A | 0044165 | cellular_component | host cell endoplasmic reticulum |
| A | 0090729 | molecular_function | toxin activity |
| B | 0003950 | molecular_function | NAD+ ADP-ribosyltransferase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0008289 | molecular_function | lipid binding |
| B | 0009986 | cellular_component | cell surface |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0030430 | cellular_component | host cell cytoplasm |
| B | 0033099 | cellular_component | attachment organelle |
| B | 0042995 | cellular_component | cell projection |
| B | 0044075 | biological_process | symbiont-mediated perturbation of host vacuole organization |
| B | 0044164 | cellular_component | host cell cytosol |
| B | 0044165 | cellular_component | host cell endoplasmic reticulum |
| B | 0090729 | molecular_function | toxin activity |
| C | 0003950 | molecular_function | NAD+ ADP-ribosyltransferase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005576 | cellular_component | extracellular region |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0008289 | molecular_function | lipid binding |
| C | 0009986 | cellular_component | cell surface |
| C | 0016757 | molecular_function | glycosyltransferase activity |
| C | 0016779 | molecular_function | nucleotidyltransferase activity |
| C | 0030430 | cellular_component | host cell cytoplasm |
| C | 0033099 | cellular_component | attachment organelle |
| C | 0042995 | cellular_component | cell projection |
| C | 0044075 | biological_process | symbiont-mediated perturbation of host vacuole organization |
| C | 0044164 | cellular_component | host cell cytosol |
| C | 0044165 | cellular_component | host cell endoplasmic reticulum |
| C | 0090729 | molecular_function | toxin activity |
| D | 0003950 | molecular_function | NAD+ ADP-ribosyltransferase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005576 | cellular_component | extracellular region |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0008289 | molecular_function | lipid binding |
| D | 0009986 | cellular_component | cell surface |
| D | 0016757 | molecular_function | glycosyltransferase activity |
| D | 0016779 | molecular_function | nucleotidyltransferase activity |
| D | 0030430 | cellular_component | host cell cytoplasm |
| D | 0033099 | cellular_component | attachment organelle |
| D | 0042995 | cellular_component | cell projection |
| D | 0044075 | biological_process | symbiont-mediated perturbation of host vacuole organization |
| D | 0044164 | cellular_component | host cell cytosol |
| D | 0044165 | cellular_component | host cell endoplasmic reticulum |
| D | 0090729 | molecular_function | toxin activity |
| E | 0003950 | molecular_function | NAD+ ADP-ribosyltransferase activity |
| E | 0005515 | molecular_function | protein binding |
| E | 0005576 | cellular_component | extracellular region |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005886 | cellular_component | plasma membrane |
| E | 0008289 | molecular_function | lipid binding |
| E | 0009986 | cellular_component | cell surface |
| E | 0016757 | molecular_function | glycosyltransferase activity |
| E | 0016779 | molecular_function | nucleotidyltransferase activity |
| E | 0030430 | cellular_component | host cell cytoplasm |
| E | 0033099 | cellular_component | attachment organelle |
| E | 0042995 | cellular_component | cell projection |
| E | 0044075 | biological_process | symbiont-mediated perturbation of host vacuole organization |
| E | 0044164 | cellular_component | host cell cytosol |
| E | 0044165 | cellular_component | host cell endoplasmic reticulum |
| E | 0090729 | molecular_function | toxin activity |
| F | 0003950 | molecular_function | NAD+ ADP-ribosyltransferase activity |
| F | 0005515 | molecular_function | protein binding |
| F | 0005576 | cellular_component | extracellular region |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005886 | cellular_component | plasma membrane |
| F | 0008289 | molecular_function | lipid binding |
| F | 0009986 | cellular_component | cell surface |
| F | 0016757 | molecular_function | glycosyltransferase activity |
| F | 0016779 | molecular_function | nucleotidyltransferase activity |
| F | 0030430 | cellular_component | host cell cytoplasm |
| F | 0033099 | cellular_component | attachment organelle |
| F | 0042995 | cellular_component | cell projection |
| F | 0044075 | biological_process | symbiont-mediated perturbation of host vacuole organization |
| F | 0044164 | cellular_component | host cell cytosol |
| F | 0044165 | cellular_component | host cell endoplasmic reticulum |
| F | 0090729 | molecular_function | toxin activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 601 |
| Chain | Residue |
| A | ARG6 |
| A | PHE7 |
| A | ARG145 |
| C | MET466 |
| C | LYS467 |
| C | HOH703 |
| C | HOH710 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 602 |
| Chain | Residue |
| A | HOH1054 |
| B | LYS251 |
| B | SER265 |
| A | LYS251 |
| A | SER265 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 603 |
| Chain | Residue |
| A | TYR263 |
| A | VAL267 |
| A | ALA436 |
| A | SER438 |
| A | HOH940 |
| A | HOH1065 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 604 |
| Chain | Residue |
| A | ARG102 |
| A | ARG113 |
| A | GLN117 |
| A | GLU522 |
| A | HOH982 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 605 |
| Chain | Residue |
| A | LYS467 |
| A | LEU541 |
| A | ASN542 |
| A | VAL584 |
| A | HOH832 |
| A | HOH836 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 606 |
| Chain | Residue |
| A | ILE58 |
| A | ARG59 |
| A | THR170 |
| A | THR171 |
| A | VAL432 |
| A | THR433 |
| A | MET434 |
| A | HOH800 |
| A | HOH823 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue ACT A 607 |
| Chain | Residue |
| A | GLU156 |
| A | ALA160 |
| A | HIS161 |
| A | ASP423 |
| A | GLU424 |
| A | HIS428 |
| A | ALA429 |
| A | HOH828 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue ACT A 608 |
| Chain | Residue |
| A | ARG91 |
| A | GLU95 |
| A | TYR475 |
| A | LEU477 |
| A | PHE528 |
| A | PHE588 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 601 |
| Chain | Residue |
| B | THR342 |
| B | GLN343 |
| E | HIS179 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 602 |
| Chain | Residue |
| B | TYR263 |
| B | LEU270 |
| B | ARG435 |
| B | ALA436 |
| B | SER438 |
| B | GOL603 |
| B | HOH808 |
| site_id | AD2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 603 |
| Chain | Residue |
| A | HOH940 |
| B | LEU270 |
| B | GLU271 |
| B | ASP272 |
| B | LYS326 |
| B | ARG435 |
| B | GOL602 |
| B | HOH788 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 604 |
| Chain | Residue |
| B | ASN294 |
| B | ASN295 |
| B | ASP487 |
| B | ASN488 |
| B | HOH940 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL C 601 |
| Chain | Residue |
| C | TYR263 |
| C | ALA436 |
| C | SER438 |
| C | GOL602 |
| C | HOH915 |
| C | HOH1032 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue GOL C 602 |
| Chain | Residue |
| C | GLU271 |
| C | ASP272 |
| C | LYS326 |
| C | ARG435 |
| C | GOL601 |
| C | HOH807 |
| D | HOH845 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 603 |
| Chain | Residue |
| C | LYS467 |
| C | LEU541 |
| C | ASN542 |
| C | VAL584 |
| C | HOH812 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 604 |
| Chain | Residue |
| C | THR502 |
| C | TYR504 |
| C | TRP506 |
| C | ASP507 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 605 |
| Chain | Residue |
| C | ASN295 |
| C | ASP487 |
| C | ASN488 |
| C | GLN293 |
| C | ASN294 |
| site_id | AD9 |
| Number of Residues | 7 |
| Details | binding site for residue GOL C 606 |
| Chain | Residue |
| C | ARG547 |
| C | ASN552 |
| C | GLN554 |
| C | TYR571 |
| C | LYS573 |
| C | HOH955 |
| C | HOH1028 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL C 607 |
| Chain | Residue |
| A | HIS159 |
| C | PHE108 |
| C | ASP112 |
| C | ARG113 |
| C | GLU114 |
| C | HOH957 |
| site_id | AE2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 D 601 |
| Chain | Residue |
| C | LYS251 |
| C | SER265 |
| D | LYS251 |
| D | SER265 |
| site_id | AE3 |
| Number of Residues | 6 |
| Details | binding site for residue GOL D 602 |
| Chain | Residue |
| D | TYR263 |
| D | LEU270 |
| D | ALA436 |
| D | SER438 |
| D | HOH845 |
| D | HOH981 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL D 603 |
| Chain | Residue |
| D | ASN32 |
| D | PHE33 |
| D | PHE34 |
| D | TRP195 |
| D | LEU207 |
| D | SER208 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL D 604 |
| Chain | Residue |
| D | ARG102 |
| D | ARG113 |
| D | GLN117 |
| D | GLU522 |
| site_id | AE6 |
| Number of Residues | 8 |
| Details | binding site for residue GOL D 605 |
| Chain | Residue |
| D | LYS467 |
| D | LEU541 |
| D | ASN542 |
| D | LEU583 |
| D | VAL584 |
| D | ASP586 |
| D | HOH819 |
| D | HOH864 |
| site_id | AE7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL D 606 |
| Chain | Residue |
| D | PRO54 |
| D | THR55 |
| D | LYS365 |
| D | GLU381 |
| D | GLY384 |
| site_id | AE8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL D 607 |
| Chain | Residue |
| D | ARG547 |
| D | ASN552 |
| D | GLN554 |
| D | TYR571 |
| D | LYS573 |
| D | HOH833 |
| site_id | AE9 |
| Number of Residues | 8 |
| Details | binding site for residue ACT D 608 |
| Chain | Residue |
| D | GLU156 |
| D | ALA160 |
| D | HIS161 |
| D | ASP423 |
| D | GLU424 |
| D | HIS428 |
| D | ALA429 |
| D | HOH790 |
| site_id | AF1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 E 601 |
| Chain | Residue |
| B | MET466 |
| B | LYS467 |
| B | HOH729 |
| E | ARG6 |
| E | PHE7 |
| E | ARG145 |
| site_id | AF2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL E 602 |
| Chain | Residue |
| E | TYR263 |
| E | ALA436 |
| E | SER438 |
| E | HOH885 |
| E | HOH893 |
| site_id | AF3 |
| Number of Residues | 3 |
| Details | binding site for residue GOL E 603 |
| Chain | Residue |
| E | ARG102 |
| E | ARG113 |
| E | GLU522 |
| site_id | AF4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL E 604 |
| Chain | Residue |
| E | ASN32 |
| E | PHE33 |
| E | PHE34 |
| E | TRP195 |
| E | LEU207 |
| E | SER208 |
| site_id | AF5 |
| Number of Residues | 8 |
| Details | binding site for residue GOL E 605 |
| Chain | Residue |
| E | PHE340 |
| E | SER353 |
| E | ASN361 |
| E | GLN362 |
| E | ASP470 |
| E | GLY471 |
| E | HOH982 |
| E | HOH984 |
| site_id | AF6 |
| Number of Residues | 8 |
| Details | binding site for residue ACT E 606 |
| Chain | Residue |
| E | GLU156 |
| E | ALA160 |
| E | HIS161 |
| E | ASP423 |
| E | GLU424 |
| E | HIS428 |
| E | ALA429 |
| E | HOH783 |
| site_id | AF7 |
| Number of Residues | 6 |
| Details | binding site for residue GOL F 601 |
| Chain | Residue |
| E | HOH885 |
| F | GLU271 |
| F | ASP272 |
| F | LYS326 |
| F | ARG435 |
| F | GOL602 |
| site_id | AF8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL F 602 |
| Chain | Residue |
| F | TYR263 |
| F | ALA436 |
| F | SER438 |
| F | GOL601 |
| F | HOH791 |
| F | HOH848 |
| site_id | AF9 |
| Number of Residues | 4 |
| Details | binding site for residue GOL F 603 |
| Chain | Residue |
| E | HIS159 |
| F | ASP112 |
| F | ARG113 |
| F | GLU114 |
