4TK0

Crystal Structure of human Tankyrase 2 in complex with DPQ.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
B	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
C	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
D	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 1201

Chain	Residue
A	CYS1081
A	HIS1084
A	CYS1089
A	CYS1092

---

site_id	AC2
Number of Residues	8
Details	binding site for residue 32Z A 1202

Chain	Residue
A	SER1068
A	TYR1071
A	GLU1138
A	HIS1031
A	GLY1032
A	GLY1053
A	TYR1060
A	PHE1061

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN B 1201

Chain	Residue
B	CYS1081
B	HIS1084
B	CYS1089
B	CYS1092

---

site_id	AC4
Number of Residues	8
Details	binding site for residue 32Z B 1202

Chain	Residue
B	HIS1031
B	GLY1032
B	TYR1060
B	PHE1061
B	LYS1067
B	SER1068
B	TYR1071
B	HOH1505

---

site_id	AC5
Number of Residues	4
Details	binding site for residue ZN C 1201

Chain	Residue
C	CYS1081
C	HIS1084
C	CYS1089
C	CYS1092

---

site_id	AC6
Number of Residues	10
Details	binding site for residue 32Z C 1202

Chain	Residue
C	HIS1031
C	GLY1032
C	TYR1060
C	PHE1061
C	LYS1067
C	SER1068
C	TYR1071
C	ILE1075
C	GLU1138
C	HOH1437

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	BINDING: BINDING => ECO:0000250|UniProtKB:O95271

Chain	Residue	Details
A	CYS1081
C	HIS1084
C	CYS1089
C	CYS1092
D	CYS1081
D	HIS1084
D	CYS1089
D	CYS1092
A	HIS1084
A	CYS1089
A	CYS1092
B	CYS1081
B	HIS1084
B	CYS1089
B	CYS1092
C	CYS1081

---