4S3M
Evidence of kinetic cooperativity in dimeric Ketopantoate Reductase from Staphylococcus aureus
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0008677 | molecular_function | 2-dehydropantoate 2-reductase activity |
A | 0015940 | biological_process | pantothenate biosynthetic process |
A | 0016491 | molecular_function | oxidoreductase activity |
B | 0000166 | molecular_function | nucleotide binding |
B | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0008677 | molecular_function | 2-dehydropantoate 2-reductase activity |
B | 0015940 | biological_process | pantothenate biosynthetic process |
B | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 20 |
Details | BINDING SITE FOR RESIDUE NAP A 500 |
Chain | Residue |
A | PRO10 |
A | ALA95 |
A | ASN97 |
A | VAL115 |
A | ILE117 |
A | SER118 |
A | GLY119 |
A | LYS121 |
A | LYS169 |
A | GLU251 |
A | HOH606 |
A | GLY11 |
A | HOH609 |
A | ALA12 |
A | VAL13 |
A | ARG33 |
A | LYS36 |
A | TYR56 |
A | LYS71 |
A | GLN74 |
site_id | AC2 |
Number of Residues | 21 |
Details | BINDING SITE FOR RESIDUE NAP B 500 |
Chain | Residue |
B | GLY9 |
B | PRO10 |
B | GLY11 |
B | ALA12 |
B | VAL13 |
B | ARG33 |
B | LYS36 |
B | TYR56 |
B | VAL70 |
B | LYS71 |
B | GLN74 |
B | ALA77 |
B | ALA95 |
B | ASN97 |
B | VAL115 |
B | ILE117 |
B | SER118 |
B | GLY119 |
B | LYS121 |
B | GLU251 |
B | HOH607 |