4S22

Crystal structure of K29 linked di-Ubiquitin

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 101

Chain	Residue
A	SER65

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 102

Chain	Residue
A	LEU73

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 101

Chain	Residue
B	LEU71

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site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 102

Chain	Residue
B	GLY47

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site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO B 103

Chain	Residue
B	ALA46
B	LYS48

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site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD D 101

Chain	Residue
D	GLU16

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site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL D 102

Chain	Residue
D	ARG74
D	ALA46
D	LYS48

---

Functional Information from PROSITE/UniProt

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
A	LYS27-ASP52

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Site: {"description":"Interacts with activating enzyme"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Site: {"description":"Essential for function"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine; by PINK1","evidences":[{"source":"UniProtKB","id":"P62987","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	30
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"P62987","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	150
Details	Domain: {"description":"Ubiquitin-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU00214","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	2
Details	Modified residue: {"description":"ADP-ribosylglycine","evidences":[{"source":"UniProtKB","id":"P62987","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI7
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)"}

Chain

Residue

Details

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