4S0W
Wild type T4 lysozyme structure
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003796 | molecular_function | lysozyme activity |
| A | 0009253 | biological_process | peptidoglycan catabolic process |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0016998 | biological_process | cell wall macromolecule catabolic process |
| A | 0030430 | cellular_component | host cell cytoplasm |
| A | 0031640 | biological_process | killing of cells of another organism |
| A | 0042742 | biological_process | defense response to bacterium |
| A | 0044659 | biological_process | viral release from host cell by cytolysis |
| B | 0003796 | molecular_function | lysozyme activity |
| B | 0009253 | biological_process | peptidoglycan catabolic process |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0016998 | biological_process | cell wall macromolecule catabolic process |
| B | 0030430 | cellular_component | host cell cytoplasm |
| B | 0031640 | biological_process | killing of cells of another organism |
| B | 0042742 | biological_process | defense response to bacterium |
| B | 0044659 | biological_process | viral release from host cell by cytolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 201 |
| Chain | Residue |
| A | THR142 |
| A | PRO143 |
| A | ASN144 |
| A | ARG145 |
| A | GOL207 |
| A | HOH437 |
| A | HOH454 |
| B | LYS162 |
| B | HOH358 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 202 |
| Chain | Residue |
| A | ARG14 |
| A | LEU15 |
| A | LYS16 |
| A | HOH331 |
| B | GLN69 |
| B | HOH350 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 203 |
| Chain | Residue |
| A | THR157 |
| A | TRP158 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EPE A 204 |
| Chain | Residue |
| A | GLY30 |
| A | HIS31 |
| A | LEU32 |
| A | ASP70 |
| A | PHE104 |
| A | GLN105 |
| A | HOH412 |
| A | HOH414 |
| A | HOH418 |
| B | THR109 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 205 |
| Chain | Residue |
| A | SER36 |
| B | SER117 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 206 |
| Chain | Residue |
| A | SER117 |
| A | HOH307 |
| B | SER36 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 207 |
| Chain | Residue |
| A | LEU79 |
| A | LYS85 |
| A | ASN144 |
| A | ARG148 |
| A | SO4201 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 201 |
| Chain | Residue |
| B | ASN144 |
| B | ARG148 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE EPE B 202 |
| Chain | Residue |
| B | GLY30 |
| B | HIS31 |
| B | LEU32 |
| B | ASP70 |
| B | PHE104 |
| B | GLN105 |
| B | MET106 |
| B | HOH316 |
| B | HOH404 |
| B | HOH405 |
| B | HOH408 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 203 |
| Chain | Residue |
| A | LYS35 |
| B | PHE114 |
| B | TRP138 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 204 |
| Chain | Residue |
| B | ARG14 |
| B | LEU15 |
| B | LYS16 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 205 |
| Chain | Residue |
| B | THR142 |
| B | PRO143 |
| B | ASN144 |
| B | ARG145 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04110, ECO:0000269|PubMed:3382407, ECO:0000269|PubMed:7831309, ECO:0000269|PubMed:8266098 |
| Chain | Residue | Details |
| A | GLU11 | |
| B | GLU11 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04110, ECO:0000269|PubMed:1892846, ECO:0000269|PubMed:3382407, ECO:0000269|PubMed:7831309, ECO:0000269|PubMed:8266098 |
| Chain | Residue | Details |
| A | ASP20 | |
| B | ASP20 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:8266098 |
| Chain | Residue | Details |
| A | LEU32 | |
| A | PHE104 | |
| B | LEU32 | |
| B | PHE104 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000303|PubMed:7831309 |
| Chain | Residue | Details |
| A | SER117 | |
| A | ASN132 | |
| B | SER117 | |
| B | ASN132 |
