4RTW

Crystal structure of the c-Src-SH3 domain E93V/Q128R mutant in complex with the high affinity peptide APP12

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006897	biological_process	endocytosis
A	0051666	biological_process	actin cortical patch localization
C	0006897	biological_process	endocytosis
C	0051666	biological_process	actin cortical patch localization

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 201

Chain	Residue
A	ARG107
A	SER140
A	ASP141
A	HOH306
A	HOH318
A	HOH323
A	HOH343
A	HOH352

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 201

Chain	Residue
C	ARG128
C	HOH315
C	HOH318
C	LYS103

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL C 202

Chain	Residue
C	THR96
C	THR98
C	ASP99
C	TRP118
C	TYR131
D	ARG7
D	ASN8

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 101

Chain	Residue
A	HOH316
D	ARG11
D	HOH201
D	HOH205

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 E 101

Chain	Residue
A	HIS122
A	HOH312
C	HOH365
D	ARG9
E	PRO6
E	ARG7
E	HOH202
E	HOH205

---