Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006508 | biological_process | proteolysis |
| A | 0007596 | biological_process | blood coagulation |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0006508 | biological_process | proteolysis |
| B | 0007596 | biological_process | blood coagulation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K A 301 |
| Chain | Residue |
| A | TYR14 |
| A | TYR14 |
| B | TYR134 |
| B | TYR134 |
| B | HOH597 |
| B | HOH597 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 302 |
| Chain | Residue |
| B | GLU127 |
| B | SER129 |
| B | PHE204 |
| B | HOH482 |
| B | HOH505 |
| A | GLU14 |
| A | ASP14 |
| B | ARG97 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 301 |
| Chain | Residue |
| B | ASP189 |
| B | ALA190 |
| B | TRP215 |
| B | GLY216 |
| B | GLY219 |
| B | HOH473 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 302 |
| Chain | Residue |
| B | ILE162 |
| B | VAL163 |
| B | ARG165 |
| B | CYS168 |
| B | PHE181 |
| B | CYS182 |
| B | HOH585 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| B | LEU53-CYS58 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| B | HIS57 | |
| B | ASP102 | |
| B | THR195 | |
| Chain | Residue | Details |
| B | ASN60 | |
