4RD0
Structure of aIF2-gamma D19A variant from Sulfolobus solfataricus bound to GDP
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000049 | molecular_function | tRNA binding |
A | 0001731 | biological_process | formation of translation preinitiation complex |
A | 0003743 | molecular_function | translation initiation factor activity |
A | 0003746 | molecular_function | translation elongation factor activity |
A | 0003924 | molecular_function | GTPase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005525 | molecular_function | GTP binding |
A | 0006412 | biological_process | translation |
A | 0006413 | biological_process | translational initiation |
A | 0006414 | biological_process | translational elongation |
A | 0016787 | molecular_function | hydrolase activity |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 23 |
Details | BINDING SITE FOR RESIDUE GDP A 501 |
Chain | Residue |
A | ALA19 |
A | VAL153 |
A | SER184 |
A | ALA185 |
A | LEU186 |
A | MG502 |
A | CL504 |
A | HOH613 |
A | HOH622 |
A | HOH646 |
A | HOH658 |
A | HIS20 |
A | HOH737 |
A | HOH777 |
A | HOH783 |
A | HOH915 |
A | GLY21 |
A | LYS22 |
A | THR23 |
A | THR24 |
A | ASN149 |
A | LYS150 |
A | ASP152 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MG A 502 |
Chain | Residue |
A | THR23 |
A | THR46 |
A | GDP501 |
A | HOH601 |
A | HOH613 |
A | HOH622 |
site_id | AC3 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE GDP A 503 |
Chain | Residue |
A | VAL223 |
A | LYS225 |
A | LYS234 |
A | SER278 |
A | ARG280 |
A | GLY282 |
A | ALA296 |
A | GLY298 |
A | HOH746 |
A | HOH926 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CL A 504 |
Chain | Residue |
A | VAL18 |
A | LYS22 |
A | GLY96 |
A | GDP501 |
A | HOH613 |
A | HOH643 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00119, ECO:0000269|PubMed:25690901, ECO:0007744|PDB:4RD1 |
Chain | Residue | Details |
A | ALA19 | |
A | GLY44 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00119, ECO:0000269|PubMed:16407071, ECO:0000269|PubMed:25690901, ECO:0007744|PDB:2AHO |
Chain | Residue | Details |
A | THR23 | |
A | THR46 |
site_id | SWS_FT_FI3 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q8U082, ECO:0000255|HAMAP-Rule:MF_00119 |
Chain | Residue | Details |
A | CYS59 | |
A | CYS62 | |
A | CYS74 | |
A | CYS77 |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00119, ECO:0000269|PubMed:25690901, ECO:0007744|PDB:4RCY, ECO:0007744|PDB:4RD1 |
Chain | Residue | Details |
A | ASN149 | |
A | SER184 |