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4RBW

Crystal structure of human alpha-defensin 5, HD5 (Thr7Arg Glu21Arg mutant)

Functional Information from GO Data
ChainGOidnamespacecontents
A0005576cellular_componentextracellular region
A0006952biological_processdefense response
B0005576cellular_componentextracellular region
B0006952biological_processdefense response
C0005576cellular_componentextracellular region
C0006952biological_processdefense response
D0005576cellular_componentextracellular region
D0006952biological_processdefense response
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 A 101
ChainResidue
AARG6
AARG7
AGLY8
AHOH201
AHOH203
BHOH218

site_idAC2
Number of Residues8
DetailsBINDING SITE FOR RESIDUE SO4 A 102
ChainResidue
AARG28
BALA11
BTHR12
BHOH217
DARG21
ATYR4
AGLY8
AARG9

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 A 103
ChainResidue
AARG7
AARG25
BARG13
DARG21
DGLY24
DARG25

site_idAC4
Number of Residues8
DetailsBINDING SITE FOR RESIDUE SO4 B 101
ChainResidue
AARG13
AARG32
BARG6
BARG7
BGLY8
BHOH202
BHOH219
BHOH222

site_idAC5
Number of Residues8
DetailsBINDING SITE FOR RESIDUE SO4 B 102
ChainResidue
AALA11
ATHR12
BTYR4
BGLY8
BARG9
BARG28
BHOH211
CARG21

site_idAC6
Number of Residues2
DetailsBINDING SITE FOR RESIDUE CL B 103
ChainResidue
BARG21
DARG9

site_idAC7
Number of Residues9
DetailsBINDING SITE FOR RESIDUE SO4 C 101
ChainResidue
BILE22
BSER23
BHOH207
CARG7
CTYR27
CHOH208
DALA11
DTHR12
DHOH205

site_idAC8
Number of Residues7
DetailsBINDING SITE FOR RESIDUE SO4 C 102
ChainResidue
AARG13
BARG7
BARG25
CARG21
CGLY24
CARG25
CHOH216

site_idAC9
Number of Residues1
DetailsBINDING SITE FOR RESIDUE CL C 103
ChainResidue
CTYR4

site_idBC1
Number of Residues10
DetailsBINDING SITE FOR RESIDUE SO4 D 101
ChainResidue
BARG21
BHOH210
BHOH214
CARG6
CARG9
DARG6
DARG7
DGLY8
DHOH209
DHOH214

site_idBC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 D 102
ChainResidue
AARG21
CGLY8
CARG9
DARG9
DARG28
DHOH202

Functional Information from PROSITE/UniProt
site_idPS00269
Number of Residues29
DetailsDEFENSIN Mammalian defensins signature. CyCrrgr.CatreslsGvCrisgrlyrlCC
ChainResidueDetails
ACYS3-CYS31

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PDB entries from 2024-11-06

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