4R54
Complex crystal structure of sp-Aspartate-Semialdehyde-Dehydrogenase with 3-carboxy-ethyl-phthalic acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004073 | molecular_function | aspartate-semialdehyde dehydrogenase activity |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009086 | biological_process | obsolete methionine biosynthetic process |
| A | 0009088 | biological_process | L-threonine biosynthetic process |
| A | 0009089 | biological_process | L-lysine biosynthetic process via diaminopimelate |
| A | 0009097 | biological_process | isoleucine biosynthetic process |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| A | 0046983 | molecular_function | protein dimerization activity |
| A | 0050661 | molecular_function | NADP binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0004073 | molecular_function | aspartate-semialdehyde dehydrogenase activity |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009086 | biological_process | obsolete methionine biosynthetic process |
| B | 0009088 | biological_process | L-threonine biosynthetic process |
| B | 0009089 | biological_process | L-lysine biosynthetic process via diaminopimelate |
| B | 0009097 | biological_process | isoleucine biosynthetic process |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0046983 | molecular_function | protein dimerization activity |
| B | 0050661 | molecular_function | NADP binding |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 401 |
| Chain | Residue |
| A | ILE273 |
| A | ALA274 |
| A | PHE276 |
| A | ALA279 |
| B | GLU343 |
| B | HOH591 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 402 |
| Chain | Residue |
| B | PHE276 |
| B | ALA279 |
| B | HOH612 |
| A | GLU343 |
| B | ILE273 |
| B | ALA274 |
| site_id | AC3 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE NAP A 403 |
| Chain | Residue |
| A | GLY9 |
| A | THR11 |
| A | GLY12 |
| A | ALA13 |
| A | VAL14 |
| A | ALA36 |
| A | SER37 |
| A | ARG39 |
| A | SER40 |
| A | THR57 |
| A | SER71 |
| A | ALA72 |
| A | GLY73 |
| A | THR76 |
| A | ASN94 |
| A | THR95 |
| A | ARG99 |
| A | PRO126 |
| A | ASN127 |
| A | CYS128 |
| A | GLY161 |
| A | MET162 |
| A | GLY329 |
| A | 3JM405 |
| A | HOH570 |
| A | HOH571 |
| A | HOH585 |
| A | HOH608 |
| A | HOH625 |
| A | HOH633 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACT A 404 |
| Chain | Residue |
| A | ASN127 |
| A | CYS128 |
| A | GLN155 |
| A | GLY159 |
| A | GLU220 |
| A | ARG245 |
| A | HIS252 |
| A | 3JM405 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 3JM A 405 |
| Chain | Residue |
| A | GLY73 |
| A | SER74 |
| A | THR95 |
| A | SER96 |
| A | ARG99 |
| A | ASN127 |
| A | GLY159 |
| A | LYS223 |
| A | NAP403 |
| A | ACT404 |
| A | HOH552 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA B 401 |
| Chain | Residue |
| B | ASP147 |
| B | SER236 |
| B | HOH524 |
| B | HOH572 |
| B | HOH602 |
| site_id | AC7 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE NAP B 402 |
| Chain | Residue |
| B | GLY9 |
| B | THR11 |
| B | GLY12 |
| B | ALA13 |
| B | ALA36 |
| B | SER37 |
| B | ARG39 |
| B | SER40 |
| B | THR57 |
| B | ALA72 |
| B | THR76 |
| B | GLY161 |
| B | MET162 |
| B | GLY163 |
| B | NAP403 |
| site_id | AC8 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE NAP B 403 |
| Chain | Residue |
| B | GLY161 |
| B | MET162 |
| B | GLY329 |
| B | NAP402 |
| B | ACT404 |
| B | HOH584 |
| B | HOH595 |
| B | GLY9 |
| B | THR11 |
| B | GLY12 |
| B | ALA13 |
| B | VAL14 |
| B | ALA36 |
| B | SER37 |
| B | SER40 |
| B | THR57 |
| B | SER71 |
| B | ALA72 |
| B | GLY73 |
| B | THR76 |
| B | ASN94 |
| B | THR95 |
| B | PRO126 |
| B | ASN127 |
| B | CYS128 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT B 404 |
| Chain | Residue |
| B | ARG99 |
| B | ASN127 |
| B | LYS223 |
| B | NAP403 |
