4R3W
Crystal Structure Analysis of the 1,2,3-tricarboxylate benzoic acid bound to sp-ASADH-2'5'-ADP complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004073 | molecular_function | aspartate-semialdehyde dehydrogenase activity |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009086 | biological_process | methionine biosynthetic process |
| A | 0009088 | biological_process | threonine biosynthetic process |
| A | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| A | 0009097 | biological_process | isoleucine biosynthetic process |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| A | 0046983 | molecular_function | protein dimerization activity |
| A | 0050661 | molecular_function | NADP binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0004073 | molecular_function | aspartate-semialdehyde dehydrogenase activity |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009086 | biological_process | methionine biosynthetic process |
| B | 0009088 | biological_process | threonine biosynthetic process |
| B | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| B | 0009097 | biological_process | isoleucine biosynthetic process |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0046983 | molecular_function | protein dimerization activity |
| B | 0050661 | molecular_function | NADP binding |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 401 |
| Chain | Residue |
| A | ILE273 |
| A | ALA274 |
| A | PHE276 |
| A | ALA279 |
| B | GLU343 |
| B | HOH569 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 3GQ A 402 |
| Chain | Residue |
| A | SER96 |
| A | ARG99 |
| A | ASN127 |
| A | GLY159 |
| A | LYS223 |
| A | GLY73 |
| A | SER74 |
| A | THR95 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 403 |
| Chain | Residue |
| A | GLU24 |
| A | SER25 |
| A | TRP332 |
| A | GLU339 |
| A | HOH503 |
| B | EDO404 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 404 |
| Chain | Residue |
| A | SER250 |
| A | GLY298 |
| A | ASP324 |
| A | LEU326 |
| A | LEU327 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT A 405 |
| Chain | Residue |
| A | ASN127 |
| A | CYS128 |
| A | GLN155 |
| A | GLY159 |
| A | GLU220 |
| A | ARG245 |
| A | HIS252 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE A2P A 406 |
| Chain | Residue |
| A | GLY9 |
| A | THR11 |
| A | GLY12 |
| A | ALA13 |
| A | ALA36 |
| A | SER37 |
| A | ARG39 |
| A | SER40 |
| A | THR57 |
| A | ALA72 |
| A | THR76 |
| A | GLY161 |
| A | MET162 |
| A | HOH580 |
| A | HOH583 |
| A | HOH595 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 401 |
| Chain | Residue |
| A | GLU343 |
| B | ILE273 |
| B | ALA274 |
| B | PHE276 |
| B | ALA279 |
| B | HOH573 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA B 402 |
| Chain | Residue |
| B | ASP147 |
| B | SER236 |
| B | HOH574 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 403 |
| Chain | Residue |
| A | LEU311 |
| A | ASP312 |
| B | THR225 |
| B | LYS229 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 404 |
| Chain | Residue |
| A | EDO403 |
| B | GLU24 |
| B | SER25 |
| B | TRP332 |
| B | GLU339 |
| B | HOH533 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 405 |
| Chain | Residue |
| B | SER250 |
| B | GLY298 |
| B | ASP324 |
| B | LEU326 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 406 |
| Chain | Residue |
| B | GLU282 |
| B | PRO291 |
| B | GLN292 |
| B | ASN295 |
| B | ALA296 |
| B | PHE303 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 407 |
| Chain | Residue |
| A | LYS229 |
| B | LEU311 |
| B | ASP312 |
| B | HOH523 |
| site_id | BC5 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE A2P B 408 |
| Chain | Residue |
| B | GLY9 |
| B | THR11 |
| B | GLY12 |
| B | ALA13 |
| B | ALA36 |
| B | SER37 |
| B | SER40 |
| B | THR57 |
| B | ALA72 |
| B | THR76 |
| B | GLY161 |
| B | MET162 |
| B | HOH567 |
