4QVH

Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0006974	biological_process	DNA damage response
A	0008643	biological_process	carbohydrate transport
A	0008897	molecular_function	holo-[acyl-carrier-protein] synthase activity
A	0009237	biological_process	siderophore metabolic process
A	0015144	molecular_function	carbohydrate transmembrane transporter activity
A	0015768	biological_process	maltose transport
A	0016020	cellular_component	membrane
A	0016740	molecular_function	transferase activity
A	0019290	biological_process	siderophore biosynthetic process
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0034219	biological_process	carbohydrate transmembrane transport
A	0034289	biological_process	detection of maltose stimulus
A	0042597	cellular_component	periplasmic space
A	0042956	biological_process	maltodextrin transmembrane transport
A	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
A	0046872	molecular_function	metal ion binding
A	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
A	0055085	biological_process	transmembrane transport
A	0060326	biological_process	cell chemotaxis
A	1901982	molecular_function	maltose binding
A	1990060	cellular_component	maltose transport complex
B	0000287	molecular_function	magnesium ion binding
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0006974	biological_process	DNA damage response
B	0008643	biological_process	carbohydrate transport
B	0008897	molecular_function	holo-[acyl-carrier-protein] synthase activity
B	0009237	biological_process	siderophore metabolic process
B	0015144	molecular_function	carbohydrate transmembrane transporter activity
B	0015768	biological_process	maltose transport
B	0016020	cellular_component	membrane
B	0016740	molecular_function	transferase activity
B	0019290	biological_process	siderophore biosynthetic process
B	0030288	cellular_component	outer membrane-bounded periplasmic space
B	0034219	biological_process	carbohydrate transmembrane transport
B	0034289	biological_process	detection of maltose stimulus
B	0042597	cellular_component	periplasmic space
B	0042956	biological_process	maltodextrin transmembrane transport
B	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
B	0046872	molecular_function	metal ion binding
B	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
B	0055085	biological_process	transmembrane transport
B	0060326	biological_process	cell chemotaxis
B	1901982	molecular_function	maltose binding
B	1990060	cellular_component	maltose transport complex

Functional Information from PROSITE/UniProt

site_id	PS01037
Number of Residues	18
Details	SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN

Chain	Residue	Details
A	PRO108-ASN125

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:24963544, ECO:0000269|PubMed:25450595, ECO:0000269|Ref.11

Chain	Residue	Details
A	ARG419
B	THR463
B	LYS532
B	LEU542
A	ARG427
A	LYS446
A	THR463
A	LYS532
A	LEU542
B	ARG419
B	ARG427
B	LYS446

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site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:25450595, ECO:0007744|PDB:4QVH

Chain	Residue	Details
A	ASP485
A	ALA486
A	GLU487
B	ASP485
B	ALA486
B	GLU487

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:24963544, ECO:0000269|Ref.11

Chain	Residue	Details
A	GLU528
B	GLU528

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