Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000292 | biological_process | RNA fragment catabolic process |
| A | 0000460 | biological_process | maturation of 5.8S rRNA |
| A | 0000467 | biological_process | exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003724 | molecular_function | RNA helicase activity |
| A | 0003729 | molecular_function | mRNA binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004386 | molecular_function | helicase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005730 | cellular_component | nucleolus |
| A | 0006364 | biological_process | rRNA processing |
| A | 0006397 | biological_process | mRNA processing |
| A | 0006401 | biological_process | RNA catabolic process |
| A | 0008143 | molecular_function | poly(A) binding |
| A | 0016075 | biological_process | rRNA catabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| A | 0031499 | cellular_component | TRAMP complex |
| A | 0034458 | molecular_function | 3'-5' RNA helicase activity |
| A | 0034475 | biological_process | U4 snRNA 3'-end processing |
| A | 0034476 | biological_process | U5 snRNA 3'-end processing |
| A | 0071028 | biological_process | nuclear mRNA surveillance |
| A | 0071031 | biological_process | nuclear mRNA surveillance of mRNA 3'-end processing |
| A | 0071035 | biological_process | nuclear polyadenylation-dependent rRNA catabolic process |
| A | 0071038 | biological_process | TRAMP-dependent tRNA surveillance pathway |
| A | 0071042 | biological_process | nuclear polyadenylation-dependent mRNA catabolic process |
| A | 0071051 | biological_process | poly(A)-dependent snoRNA 3'-end processing |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1101 |
| Chain | Residue |
| A | GLU263 |
| A | TYR266 |
| A | GLY508 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1102 |
| Chain | Residue |
| A | LYS416 |
| A | HIS476 |
| A | SER477 |
| A | THR502 |
| A | THR504 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1103 |
| Chain | Residue |
| A | LYS827 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 156 |
| Details | Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 204 |
| Details | Domain: {"description":"Helicase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Motif: {"description":"DEVH box"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
