4QQ4
CW-type zinc finger of MORC3 in complex with the amino terminus of histone H3
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 2003 |
| Chain | Residue |
| A | SER436 |
| A | ZN2005 |
| B | CYS446 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 2004 |
| Chain | Residue |
| A | CYS446 |
| A | ZN2005 |
| B | SER436 |
| site_id | AC3 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR CHAIN C OF HISTONE H3.3 |
| Chain | Residue |
| A | THR409 |
| A | TRP410 |
| A | VAL411 |
| A | GLN412 |
| A | TRP419 |
| A | ASP424 |
| A | PRO430 |
| A | GLU431 |
| A | GLU453 |
| A | HOH2103 |
| B | ASP407 |
| B | GLU431 |
| C | HOH201 |
| C | HOH202 |
| C | HOH203 |
| C | HOH204 |
| C | HOH205 |
| C | HOH206 |
| D | M3L4 |
| D | GLN5 |
| D | THR6 |
| D | ALA7 |
| A | PRO406 |
| A | ASP407 |
| A | GLN408 |
| site_id | AC4 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR CHAIN D OF HISTONE H3.3 |
| Chain | Residue |
| A | GLN428 |
| A | LEU429 |
| A | PRO430 |
| A | GLU431 |
| A | HOH2111 |
| B | PRO406 |
| B | ASP407 |
| B | GLN408 |
| B | THR409 |
| B | TRP410 |
| B | VAL411 |
| B | GLN412 |
| B | TRP419 |
| B | ASP424 |
| B | PRO430 |
| B | GLU431 |
| B | HOH2122 |
| C | ALA1 |
| C | ARG2 |
| C | THR3 |
| C | HOH201 |
| C | HOH202 |
| D | HOH201 |
| D | HOH202 |
| D | HOH204 |
| D | HOH205 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Citrulline; alternate => ECO:0000269|PubMed:16567635 |
| Chain | Residue | Details |
| C | ARG2 | |
| D | ARG2 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by HASPIN => ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:16185088 |
| Chain | Residue | Details |
| C | THR3 | |
| D | THR3 | |
| A | CYS435 | |
| A | CYS446 | |
| B | CYS413 | |
| B | CYS416 | |
| B | CYS435 | |
| B | CYS446 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16457588, ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| C | M3L4 | |
| D | M3L4 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: 5-glutamyl serotonin; alternate => ECO:0000269|PubMed:30867594 |
| Chain | Residue | Details |
| C | GLN5 | |
| D | GLN5 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by PKC => ECO:0000269|PubMed:20228790 |
| Chain | Residue | Details |
| C | THR6 | |
| D | THR6 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Symmetric dimethylarginine; by PRMT5; alternate => ECO:0000250|UniProtKB:P84244 |
| Chain | Residue | Details |
| C | ARG8 | |
| D | ARG8 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:11242053, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16457588, ECO:0000269|PubMed:17194708, ECO:0000269|PubMed:7309716 |
| Chain | Residue | Details |
| C | LYS9 | |
| D | LYS9 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; alternate; by AURKB, AURKC, RPS6KA3, RPS6KA4 and RPS6KA5 => ECO:0000269|PubMed:10464286, ECO:0000269|PubMed:11856369, ECO:0000269|PubMed:12560483, ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:15851689, ECO:0000269|PubMed:16185088 |
| Chain | Residue | Details |
| C | SER10 | |
| D | SER10 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by PKC => ECO:0000269|PubMed:12560483, ECO:0000269|PubMed:18066052, ECO:0000269|PubMed:22901803 |
| Chain | Residue | Details |
| C | THR11 | |
| D | THR11 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435 |
| Chain | Residue | Details |
| C | LYS14 | |
| D | LYS14 |
