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4QOB

Crystal structure of cPOP1

Functional Information from GO Data
ChainGOidnamespacecontents
A0002376biological_processimmune system process
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006952biological_processdefense response
A0008385cellular_componentIkappaB kinase complex
A0009968biological_processnegative regulation of signal transduction
A0010803biological_processregulation of tumor necrosis factor-mediated signaling pathway
A0010804biological_processnegative regulation of tumor necrosis factor-mediated signaling pathway
A0030291molecular_functionprotein serine/threonine kinase inhibitor activity
A0032088biological_processobsolete negative regulation of NF-kappaB transcription factor activity
A0032691biological_processnegative regulation of interleukin-1 beta production
A0032731biological_processpositive regulation of interleukin-1 beta production
A0043124biological_processnegative regulation of canonical NF-kappaB signal transduction
A0045087biological_processinnate immune response
A0051707biological_processresponse to other organism
A0120283molecular_functionprotein serine/threonine kinase binding
A1900226biological_processnegative regulation of NLRP3 inflammasome complex assembly
A2000660biological_processnegative regulation of interleukin-1-mediated signaling pathway
B0002376biological_processimmune system process
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006952biological_processdefense response
B0008385cellular_componentIkappaB kinase complex
B0009968biological_processnegative regulation of signal transduction
B0010803biological_processregulation of tumor necrosis factor-mediated signaling pathway
B0010804biological_processnegative regulation of tumor necrosis factor-mediated signaling pathway
B0030291molecular_functionprotein serine/threonine kinase inhibitor activity
B0032088biological_processobsolete negative regulation of NF-kappaB transcription factor activity
B0032691biological_processnegative regulation of interleukin-1 beta production
B0032731biological_processpositive regulation of interleukin-1 beta production
B0043124biological_processnegative regulation of canonical NF-kappaB signal transduction
B0045087biological_processinnate immune response
B0051707biological_processresponse to other organism
B0120283molecular_functionprotein serine/threonine kinase binding
B1900226biological_processnegative regulation of NLRP3 inflammasome complex assembly
B2000660biological_processnegative regulation of interleukin-1-mediated signaling pathway

249697

PDB entries from 2026-02-25

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