4QDS

Physical basis for Nrp2 ligand binding

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001525	biological_process	angiogenesis
A	0005021	molecular_function	vascular endothelial growth factor receptor activity
A	0007411	biological_process	axon guidance
A	0017154	molecular_function	semaphorin receptor activity
A	0038084	biological_process	vascular endothelial growth factor signaling pathway
B	0001525	biological_process	angiogenesis
B	0005021	molecular_function	vascular endothelial growth factor receptor activity
B	0007411	biological_process	axon guidance
B	0017154	molecular_function	semaphorin receptor activity
B	0038084	biological_process	vascular endothelial growth factor signaling pathway

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE GOL A 501

Chain	Residue
A	HIS312

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ACT B 501

Chain	Residue
A	GLY369
B	THR391

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Functional Information from PROSITE/UniProt

site_id	PS01285
Number of Residues	30
Details	FA58C_1 Coagulation factors 5/8 type C domain (FA58C) signature 1. GWtpnldsnke......YLqVDlrfltmLtaIaTQG

Chain	Residue	Details
A	GLY317-GLY346

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site_id	PS01286
Number of Residues	17
Details	FA58C_2 Coagulation factors 5/8 type C domain (FA58C) signature 2. Pqtwhsgia..LRlELfGC

Chain	Residue	Details
A	PRO411-CYS427

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	300
Details	Domain: {"description":"F5/8 type C 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00081","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	38
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	24
Details	Compositional bias: {"description":"Polar residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

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