4Q3M
Crystal structure of MGS-M4, an aldo-keto reductase enzyme from a Medee basin deep-sea metagenome library
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 301 |
| Chain | Residue |
| A | ALA185 |
| A | PRO186 |
| A | LEU187 |
| A | MET188 |
| A | SER189 |
| A | PRO229 |
| A | LYS230 |
| A | HOH504 |
| A | HOH531 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 301 |
| Chain | Residue |
| B | ALA185 |
| B | PRO186 |
| B | LEU187 |
| B | MET188 |
| B | SER189 |
| B | PRO229 |
| B | LYS230 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 301 |
| Chain | Residue |
| C | ALA185 |
| C | PRO186 |
| C | LEU187 |
| C | MET188 |
| C | SER189 |
| C | LYS230 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 D 301 |
| Chain | Residue |
| D | ALA185 |
| D | PRO186 |
| D | LEU187 |
| D | MET188 |
| D | SER189 |
| D | PRO229 |
| D | LYS230 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 E 301 |
| Chain | Residue |
| E | ALA185 |
| E | PRO186 |
| E | LEU187 |
| E | MET188 |
| E | SER189 |
| E | PRO229 |
| E | LYS230 |
| E | HOH508 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA F 301 |
| Chain | Residue |
| F | MET12 |
| F | HIS41 |
| F | ASP43 |
| F | THR71 |
| F | GLU182 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 F 302 |
| Chain | Residue |
| F | ALA185 |
| F | PRO186 |
| F | LEU187 |
| F | MET188 |
| F | SER189 |
| F | PRO229 |
| F | LYS230 |
| F | HOH452 |
| F | HOH528 |
Functional Information from PROSITE/UniProt
| site_id | PS00062 |
| Number of Residues | 18 |
| Details | ALDOKETO_REDUCTASE_2 Aldo/keto reductase family signature 2. FetlyeegkVKAIGVSNF |
| Chain | Residue | Details |
| A | PHE121-PHE138 |
| site_id | PS00063 |
| Number of Residues | 16 |
| Details | ALDOKETO_REDUCTASE_3 Aldo/keto reductase family putative active site signature. IPKSITpeRIvQNfDV |
| Chain | Residue | Details |
| A | ILE228-VAL243 |
| site_id | PS00798 |
| Number of Residues | 18 |
| Details | ALDOKETO_REDUCTASE_1 Aldo/keto reductase family signature 1. GYRHIDTAmiygnEeeVG |
| Chain | Residue | Details |
| A | GLY38-GLY55 |
