4PXQ

Crystal structure of D-glucuronyl C5-epimerase in complex with heparin hexasaccharide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0005794	cellular_component	Golgi apparatus
A	0015012	biological_process	heparan sulfate proteoglycan biosynthetic process
A	0016853	molecular_function	isomerase activity
A	0030210	biological_process	heparin proteoglycan biosynthetic process
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
A	0047464	molecular_function	heparosan-N-sulfate-glucuronate 5-epimerase activity
B	0000139	cellular_component	Golgi membrane
B	0005794	cellular_component	Golgi apparatus
B	0015012	biological_process	heparan sulfate proteoglycan biosynthetic process
B	0016853	molecular_function	isomerase activity
B	0030210	biological_process	heparin proteoglycan biosynthetic process
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
B	0047464	molecular_function	heparosan-N-sulfate-glucuronate 5-epimerase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PDB","id":"4PXQ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"O94923","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	8
Details	Site: {"description":"Critical for catalysis","evidences":[{"source":"PubMed","id":"25568314","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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