Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
B | 0000166 | molecular_function | nucleotide binding |
B | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
B | 0016491 | molecular_function | oxidoreductase activity |
B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 26 |
Details | BINDING SITE FOR RESIDUE NAD A 601 |
Chain | Residue |
A | ILE162 |
A | THR226 |
A | GLY229 |
A | GLN230 |
A | PHE243 |
A | THR244 |
A | GLY245 |
A | SER246 |
A | ALA249 |
A | MET252 |
A | VAL253 |
A | THR163 |
A | GLU267 |
A | LEU268 |
A | SER269 |
A | CYS301 |
A | GLU397 |
A | PHE399 |
A | PHE466 |
A | ALA164 |
A | PHE165 |
A | ASN166 |
A | LYS189 |
A | GLY190 |
A | ALA191 |
A | PRO192 |
site_id | AC2 |
Number of Residues | 25 |
Details | BINDING SITE FOR RESIDUE NAD B 601 |
Chain | Residue |
B | ILE162 |
B | THR163 |
B | ALA164 |
B | PHE165 |
B | ASN166 |
B | LYS189 |
B | GLY190 |
B | ALA191 |
B | THR226 |
B | GLY229 |
B | GLN230 |
B | PHE243 |
B | THR244 |
B | GLY245 |
B | SER246 |
B | ALA249 |
B | MET252 |
B | VAL253 |
B | GLU267 |
B | LEU268 |
B | SER269 |
B | CYS301 |
B | GLU397 |
B | PHE399 |
B | PHE466 |
Functional Information from PROSITE/UniProt
site_id | PS00687 |
Number of Residues | 8 |
Details | ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. LELSGNNA |
Chain | Residue | Details |
A | LEU266-ALA273 | |