Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4PWC

Phl p 4 I153V N158H variant, a glucose oxidase, 3.5 M NaBr soak

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0016491	molecular_function	oxidoreductase activity
A	0050660	molecular_function	flavin adenine dinucleotide binding
A	0071949	molecular_function	FAD binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	32
Details	BINDING SITE FOR RESIDUE FAD A 601

Chain	Residue
A	VAL81
A	LEU106
A	SER125
A	GLY148
A	VAL149
A	CYS150
A	VAL153
A	GLY154
A	GLY157
A	HIS158
A	GLY163
A	ARG82
A	PHE164
A	GLY209
A	GLU210
A	GLY213
A	VAL215
A	TYR436
A	ASN438
A	ARG440
A	ASN489
A	BR604
A	SER83
A	HOH702
A	HOH732
A	HOH755
A	GLY84
A	GLY85
A	HIS86
A	ASP87
A	TYR88
A	SER92

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 602

Chain	Residue
A	GLU89
A	GLU338
A	HOH747
A	HOH758
A	HOH759
A	HOH765

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 603

Chain	Residue
A	LYS430
A	HOH757
A	HOH795
A	HOH831
A	HOH839
A	HOH842

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BR A 604

Chain	Residue
A	GLY148
A	VAL149
A	CYS150
A	HIS158
A	FAD601

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 605

Chain	Residue
A	ALA409
A	ALA412

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 606

Chain	Residue
A	PRO151
A	HIS315

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 607

Chain	Residue
A	ASP244

site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 608

Chain	Residue
A	LYS291

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 610

Chain	Residue
A	GLY209
A	ASN438
A	ARG440

site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 611

Chain	Residue
A	LYS282

site_id	BC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 613

Chain	Residue
A	GLU304

site_id	BC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 614

Chain	Residue
A	PRO269

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 616

Chain	Residue
A	LEU322

site_id	BC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 617

Chain	Residue
A	TYR339

site_id	BC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 618

Chain	Residue
A	ASN303
A	PHE313

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 619

Chain	Residue
A	LYS27
A	LYS52

site_id	BC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 620

Chain	Residue
A	LYS193

site_id	BC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 621

Chain	Residue
A	PRO426

site_id	CC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 624

Chain	Residue
A	PRO286

site_id	CC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 625

Chain	Residue
A	ASN451
A	ASP452

site_id	CC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 626

Chain	Residue
A	SER306
A	GLN309

site_id	CC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 627

Chain	Residue
A	ARG73
A	PRO364

site_id	CC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 628

Chain	Residue
A	LYS468
A	GLU472

site_id	CC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 629

Chain	Residue
A	SER235

site_id	CC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 630

Chain	Residue
A	PRO347

site_id	CC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 632

Chain	Residue
A	ARG22

site_id	CC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR A 633

Chain	Residue
A	ASN328
A	ARG329
A	GLN330
A	HOH770

site_id	DC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 634

Chain	Residue
A	TYR345
A	GLN346
A	VAL428

site_id	DC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 635

Chain	Residue
A	GLY393

site_id	DC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 637

Chain	Residue
A	GLU383
A	LYS468
A	GLY469

site_id	DC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR A 638

Chain	Residue
A	VAL112
A	VAL114
A	LYS138
A	HOH760

site_id	DC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 639

Chain	Residue
A	GLN97
A	ARG446

site_id	DC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 640

Chain	Residue
A	ALA31
A	PRO30

site_id	DC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 641

Chain	Residue
A	VAL243
A	ASN358

site_id	DC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 642

Chain	Residue
A	THR228
A	MET305

site_id	DC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 643

Chain	Residue
A	GLN38
A	ASN107
A	LYS108

site_id	EC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 644

Chain	Residue
A	ARG433
A	LYS465

site_id	EC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 645

Chain	Residue
A	LYS468

site_id	EC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 646

Chain	Residue
A	THR120
A	TRP122
A	GLN219

site_id	EC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 647

Chain	Residue
A	GLN66
A	LEU190
A	SER239

site_id	EC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 649

Chain	Residue
A	HIS200

site_id	EC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 650

Chain	Residue
A	ARG94

site_id	EC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 651

Chain	Residue
A	GLN97
A	ARG446

site_id	EC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 652

Chain	Residue
A	VAL449

site_id	EC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 653

Chain	Residue
A	ASP259

site_id	FC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 654

Chain	Residue
A	LYS460

site_id	FC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 655

Chain	Residue
A	LYS193

site_id	FC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 656

Chain	Residue
A	ARG74
A	THR76
A	GLY365

site_id	FC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 658

Chain	Residue
A	VAL62

site_id	FC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 659

Chain	Residue
A	LYS194
A	SER195

site_id	FC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 660

Chain	Residue
A	LYS340

site_id	FC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 661

Chain	Residue
A	ASP10
A	PHE405

site_id	FC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 662

Chain	Residue
A	ASN431

site_id	FC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 663

Chain	Residue
A	PRO227

site_id	GC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 665

Chain	Residue
A	SER46
A	LYS334

site_id	GC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 666

Chain	Residue
A	ARG44
A	PRO407
A	ALA410

site_id	GC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 667

Chain	Residue
A	GLY393

site_id	GC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 668

Chain	Residue
A	ASP199
A	ARG473

site_id	GC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 670

Chain	Residue
A	HOH847

site_id	GC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 671

Chain	Residue
A	CYS14
A	ARG74
A	HIS75

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)