4PT4

Crystal structure Analysis of N terminal region containing the dimerization domain and DNA binding domain of HU protein(Histone like protein-DNA binding) from Mycobacterium tuberculosis [H37Ra]

Replaces:  3C4I

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0030527	molecular_function	structural constituent of chromatin
B	0003677	molecular_function	DNA binding
B	0030527	molecular_function	structural constituent of chromatin

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE FMT A 100

Chain	Residue
B	ARG54

---

site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE FMT A 101

Chain	Residue
A	LYS72

---

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FMT B 100

Chain	Residue
B	HOH217
B	HOH228

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FMT B 101

Chain	Residue
B	ARG55
B	ARG58
B	VAL71
B	LYS72
B	THR74

---

Functional Information from PROSITE/UniProt

site_id	PS00045
Number of Residues	20
Details	HISTONE_LIKE Bacterial histone-like DNA-binding proteins signature. GFgvFeqrrRaaRv.ArNPrT

Chain	Residue	Details
A	GLY46-THR65

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"PubMed","id":"34224344","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"24816602","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"26817737","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---