4PO2

Crystal Structure of the Stress-Inducible Human Heat Shock Protein HSP70 Substrate-Binding Domain in Complex with Peptide Substrate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0140662	molecular_function	ATP-dependent protein folding chaperone
B	0005524	molecular_function	ATP binding
B	0140662	molecular_function	ATP-dependent protein folding chaperone

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 701

Chain	Residue
A	ARG458
B	GLN424

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PO4 A 702

Chain	Residue
A	ARG533
A	SER537

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site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 B 701

Chain	Residue
B	GLU554
B	HOH957
B	HOH1029
A	GLU593
A	ARG596
A	LYS597
B	LYS550
B	SER551

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: Omega-N-methylarginine => ECO:0007744|PubMed:24129315

Chain	Residue	Details
A	ARG469
B	ARG469

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N6,N6-dimethyllysine; alternate => ECO:0007744|PubMed:24129315

Chain	Residue	Details
A	LYS561
B	LYS561

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