4PM5

Crystal structure of CTX-M-14 S70G beta-lactamase in complex with cefotaxime at 1.26 Angstroms resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008800	molecular_function	beta-lactamase activity
A	0016787	molecular_function	hydrolase activity
A	0017001	biological_process	antibiotic catabolic process
A	0030655	biological_process	beta-lactam antibiotic catabolic process
A	0046677	biological_process	response to antibiotic

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	binding site for residue CE3 A 301

Chain	Residue
A	CYS69
A	LYS234
A	THR235
A	GLY236
A	SER237
A	GLY238
A	ASP240
A	HOH639
A	HOH646
A	HOH752
A	HOH753
A	GLY70
A	HOH771
A	ASN104
A	TYR105
A	SER130
A	ASN132
A	PRO167
A	ASN170
A	THR216

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site_id	AC2
Number of Residues	7
Details	binding site for residue SO4 A 302

Chain	Residue
A	GLN25
A	THR26
A	ASN271
A	SO4303
A	SO4304
A	HOH409
A	HOH410

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site_id	AC3
Number of Residues	10
Details	binding site for residue SO4 A 303

Chain	Residue
A	THR209
A	LYS212
A	GLN270
A	ASN271
A	SO4302
A	HOH401
A	HOH402
A	HOH404
A	HOH409
A	HOH410

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site_id	AC4
Number of Residues	5
Details	binding site for residue SO4 A 304

Chain	Residue
A	THR26
A	ASN271
A	SO4302
A	HOH405
A	HOH419

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