Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016303 | molecular_function | 1-phosphatidylinositol-3-kinase activity |
| B | 0046854 | biological_process | phosphatidylinositol phosphate biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 901 |
| Chain | Residue |
| B | GLN686 |
| B | VAL688 |
| B | THR752 |
| B | LYS753 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue 2UG B 902 |
| Chain | Residue |
| B | PHE684 |
| B | ILE685 |
| B | SER687 |
| B | LEU750 |
| B | ILE760 |
| B | ASP761 |
| B | HOH1015 |
| B | HOH1024 |
| B | HOH1050 |
| B | ILE634 |
| B | LYS636 |
| B | TYR670 |
| B | MET682 |
| B | GLN683 |
Functional Information from PROSITE/UniProt
| site_id | PS00915 |
| Number of Residues | 15 |
| Details | PI3_4_KINASE_1 Phosphatidylinositol 3- and 4-kinases signature 1. FKhg.DDLRQDqlilQ |
| Chain | Residue | Details |
| B | PHE635-GLN649 | |
| site_id | PS00916 |
| Number of Residues | 21 |
| Details | PI3_4_KINASE_2 Phosphatidylinositol 3- and 4-kinases signature 2. ScAgycVitYILgVgDRHldN |
| Chain | Residue | Details |
| B | SER728-ASN748 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 266 |
| Details | Domain: {"description":"PI3K/PI4K catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00269","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Region: {"description":"G-loop","evidences":[{"source":"PROSITE-ProRule","id":"PRU00269","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Region: {"description":"Catalytic loop","evidences":[{"source":"PROSITE-ProRule","id":"PRU00269","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 21 |
| Details | Region: {"description":"Activation loop","evidences":[{"source":"PROSITE-ProRule","id":"PRU00269","evidenceCode":"ECO:0000255"}]} |
