4PDK
FadR, Fatty Acid Responsive Transcription Factor from Vibrio cholerae, in Complex with oleoyl-CoA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000062 | molecular_function | fatty-acyl-CoA binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0019217 | biological_process | regulation of fatty acid metabolic process |
| A | 0071072 | biological_process | negative regulation of phospholipid biosynthetic process |
| B | 0000062 | molecular_function | fatty-acyl-CoA binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0019217 | biological_process | regulation of fatty acid metabolic process |
| B | 0071072 | biological_process | negative regulation of phospholipid biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | binding site for residue 3VV A 301 |
| Chain | Residue |
| A | LEU101 |
| A | SER151 |
| A | PRO152 |
| A | ASP185 |
| A | LEU208 |
| A | TYR212 |
| A | GLY216 |
| A | TYR219 |
| A | PHE220 |
| A | ARG253 |
| A | GLY256 |
| A | LEU102 |
| A | SER259 |
| A | GLY260 |
| A | TRP263 |
| B | TYR115 |
| B | LYS118 |
| B | ARG245 |
| A | ALA103 |
| A | ARG105 |
| A | THR106 |
| A | ILE108 |
| A | SER134 |
| A | ALA137 |
| A | ALA150 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue 3VV A 302 |
| Chain | Residue |
| A | ASN130 |
| A | SER134 |
| A | TYR153 |
| A | LYS156 |
| A | TYR184 |
| A | ARG191 |
| A | PHE194 |
| A | HIS195 |
| A | ILE200 |
| A | GLY207 |
| B | TRP21 |
| B | PRO27 |
| B | ILE82 |
| B | 3VV302 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | binding site for residue 3VV B 301 |
| Chain | Residue |
| A | ILE111 |
| A | ARG114 |
| A | TYR115 |
| A | ILE204 |
| A | ARG245 |
| B | LEU101 |
| B | LEU102 |
| B | ALA104 |
| B | ARG105 |
| B | THR106 |
| B | ILE108 |
| B | PHE205 |
| B | TYR212 |
| B | TYR219 |
| B | ARG253 |
| B | GLY256 |
| B | ILE257 |
| B | SER259 |
| B | GLY260 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | binding site for residue 3VV B 302 |
| Chain | Residue |
| A | PRO27 |
| A | MET75 |
| A | 3VV302 |
| B | ARG126 |
| B | ASN130 |
| B | SER134 |
| B | TYR153 |
| B | TYR184 |
| B | ARG191 |
| B | PHE194 |
| B | HIS195 |
| B | GLN199 |
| B | ILE204 |
| B | LEU208 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 38 |
| Details | DNA_BIND: H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00696 |
| Chain | Residue | Details |
| A | GLU34-GLN53 | |
| B | GLU34-GLN53 |
