4PC6
Elongation factor Tu:Ts complex with bound GDPNP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003746 | molecular_function | translation elongation factor activity |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006412 | biological_process | translation |
| A | 0006414 | biological_process | translational elongation |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0032045 | cellular_component | guanyl-nucleotide exchange factor complex |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0097216 | molecular_function | guanosine tetraphosphate binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003746 | molecular_function | translation elongation factor activity |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006412 | biological_process | translation |
| B | 0006414 | biological_process | translational elongation |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0032045 | cellular_component | guanyl-nucleotide exchange factor complex |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0097216 | molecular_function | guanosine tetraphosphate binding |
| C | 0003746 | molecular_function | translation elongation factor activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006412 | biological_process | translation |
| C | 0006414 | biological_process | translational elongation |
| D | 0003746 | molecular_function | translation elongation factor activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006412 | biological_process | translation |
| D | 0006414 | biological_process | translational elongation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue GNP A 401 |
| Chain | Residue |
| A | HIS19 |
| A | ASP138 |
| A | MET139 |
| A | SER173 |
| A | ALA174 |
| A | LEU175 |
| A | HOH501 |
| A | VAL20 |
| A | ASP21 |
| A | GLY23 |
| A | LYS24 |
| A | THR25 |
| A | THR26 |
| A | ASN135 |
| A | LYS136 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 301 |
| Chain | Residue |
| C | GLU178 |
| C | PHE255 |
| C | HOH410 |
| C | HOH426 |
| D | GLN203 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | binding site for residue GNP B 401 |
| Chain | Residue |
| B | HIS19 |
| B | VAL20 |
| B | ASP21 |
| B | GLY23 |
| B | LYS24 |
| B | THR25 |
| B | THR26 |
| B | ASN135 |
| B | LYS136 |
| B | ASP138 |
| B | MET139 |
| B | SER173 |
| B | ALA174 |
| B | LEU175 |
| D | GLU274 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 402 |
| Chain | Residue |
| B | GLY316 |
| B | GLY317 |
| B | HIS319 |
| B | GLU378 |
| B | ARG381 |
| B | HOH557 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL D 301 |
| Chain | Residue |
| C | GLN203 |
| D | GLU178 |
| D | GLY254 |
| D | PHE255 |
| D | GOL302 |
| D | HOH485 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue GOL D 302 |
| Chain | Residue |
| C | SER204 |
| C | LYS206 |
| D | PHE255 |
| D | ILE256 |
| D | ARG257 |
| D | GOL301 |
| D | HOH415 |
Functional Information from PROSITE/UniProt
| site_id | PS00301 |
| Number of Residues | 16 |
| Details | G_TR_1 Translational (tr)-type guanine nucleotide-binding (G) domain signature. DNapeEKaRGITIntS |
| Chain | Residue | Details |
| A | ASP50-SER65 |
| site_id | PS01126 |
| Number of Residues | 16 |
| Details | EF_TS_1 Elongation factor Ts signature 1. LRerTGaGMmDcKKAL |
| Chain | Residue | Details |
| C | LEU11-LEU26 |
| site_id | PS01127 |
| Number of Residues | 11 |
| Details | EF_TS_2 Elongation factor Ts signature 2. EVNCQTDFVAK |
| Chain | Residue | Details |
| C | GLU74-LYS84 |
