4P18
Crystal Structure of frog M ferritin mutant D80K
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004322 | molecular_function | ferroxidase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006826 | biological_process | iron ion transport |
| A | 0006879 | biological_process | intracellular iron ion homeostasis |
| A | 0006880 | biological_process | intracellular sequestering of iron ion |
| A | 0008198 | molecular_function | ferrous iron binding |
| A | 0008199 | molecular_function | ferric iron binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004322 | molecular_function | ferroxidase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006826 | biological_process | iron ion transport |
| B | 0006879 | biological_process | intracellular iron ion homeostasis |
| B | 0006880 | biological_process | intracellular sequestering of iron ion |
| B | 0008198 | molecular_function | ferrous iron binding |
| B | 0008199 | molecular_function | ferric iron binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004322 | molecular_function | ferroxidase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006826 | biological_process | iron ion transport |
| C | 0006879 | biological_process | intracellular iron ion homeostasis |
| C | 0006880 | biological_process | intracellular sequestering of iron ion |
| C | 0008198 | molecular_function | ferrous iron binding |
| C | 0008199 | molecular_function | ferric iron binding |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0004322 | molecular_function | ferroxidase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006826 | biological_process | iron ion transport |
| D | 0006879 | biological_process | intracellular iron ion homeostasis |
| D | 0006880 | biological_process | intracellular sequestering of iron ion |
| D | 0008198 | molecular_function | ferrous iron binding |
| D | 0008199 | molecular_function | ferric iron binding |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0004322 | molecular_function | ferroxidase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0006826 | biological_process | iron ion transport |
| E | 0006879 | biological_process | intracellular iron ion homeostasis |
| E | 0006880 | biological_process | intracellular sequestering of iron ion |
| E | 0008198 | molecular_function | ferrous iron binding |
| E | 0008199 | molecular_function | ferric iron binding |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0004322 | molecular_function | ferroxidase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0006826 | biological_process | iron ion transport |
| F | 0006879 | biological_process | intracellular iron ion homeostasis |
| F | 0006880 | biological_process | intracellular sequestering of iron ion |
| F | 0008198 | molecular_function | ferrous iron binding |
| F | 0008199 | molecular_function | ferric iron binding |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0046872 | molecular_function | metal ion binding |
| G | 0004322 | molecular_function | ferroxidase activity |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0006826 | biological_process | iron ion transport |
| G | 0006879 | biological_process | intracellular iron ion homeostasis |
| G | 0006880 | biological_process | intracellular sequestering of iron ion |
| G | 0008198 | molecular_function | ferrous iron binding |
| G | 0008199 | molecular_function | ferric iron binding |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0046872 | molecular_function | metal ion binding |
| H | 0004322 | molecular_function | ferroxidase activity |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0006826 | biological_process | iron ion transport |
| H | 0006879 | biological_process | intracellular iron ion homeostasis |
| H | 0006880 | biological_process | intracellular sequestering of iron ion |
| H | 0008198 | molecular_function | ferrous iron binding |
| H | 0008199 | molecular_function | ferric iron binding |
| H | 0016491 | molecular_function | oxidoreductase activity |
| H | 0046872 | molecular_function | metal ion binding |
| I | 0004322 | molecular_function | ferroxidase activity |
| I | 0005737 | cellular_component | cytoplasm |
| I | 0006826 | biological_process | iron ion transport |
| I | 0006879 | biological_process | intracellular iron ion homeostasis |
| I | 0006880 | biological_process | intracellular sequestering of iron ion |
| I | 0008198 | molecular_function | ferrous iron binding |
| I | 0008199 | molecular_function | ferric iron binding |
| I | 0016491 | molecular_function | oxidoreductase activity |
| I | 0046872 | molecular_function | metal ion binding |
| J | 0004322 | molecular_function | ferroxidase activity |
| J | 0005737 | cellular_component | cytoplasm |
| J | 0006826 | biological_process | iron ion transport |
| J | 0006879 | biological_process | intracellular iron ion homeostasis |
| J | 0006880 | biological_process | intracellular sequestering of iron ion |
| J | 0008198 | molecular_function | ferrous iron binding |
| J | 0008199 | molecular_function | ferric iron binding |
| J | 0016491 | molecular_function | oxidoreductase activity |
| J | 0046872 | molecular_function | metal ion binding |
| K | 0004322 | molecular_function | ferroxidase activity |
| K | 0005737 | cellular_component | cytoplasm |
| K | 0006826 | biological_process | iron ion transport |
| K | 0006879 | biological_process | intracellular iron ion homeostasis |
| K | 0006880 | biological_process | intracellular sequestering of iron ion |
| K | 0008198 | molecular_function | ferrous iron binding |
| K | 0008199 | molecular_function | ferric iron binding |
| K | 0016491 | molecular_function | oxidoreductase activity |
| K | 0046872 | molecular_function | metal ion binding |
| L | 0004322 | molecular_function | ferroxidase activity |
| L | 0005737 | cellular_component | cytoplasm |
| L | 0006826 | biological_process | iron ion transport |
| L | 0006879 | biological_process | intracellular iron ion homeostasis |
| L | 0006880 | biological_process | intracellular sequestering of iron ion |
| L | 0008198 | molecular_function | ferrous iron binding |
| L | 0008199 | molecular_function | ferric iron binding |
| L | 0016491 | molecular_function | oxidoreductase activity |
| L | 0046872 | molecular_function | metal ion binding |
| M | 0004322 | molecular_function | ferroxidase activity |
| M | 0005737 | cellular_component | cytoplasm |
| M | 0006826 | biological_process | iron ion transport |
| M | 0006879 | biological_process | intracellular iron ion homeostasis |
| M | 0006880 | biological_process | intracellular sequestering of iron ion |
| M | 0008198 | molecular_function | ferrous iron binding |
| M | 0008199 | molecular_function | ferric iron binding |
| M | 0016491 | molecular_function | oxidoreductase activity |
| M | 0046872 | molecular_function | metal ion binding |
| N | 0004322 | molecular_function | ferroxidase activity |
| N | 0005737 | cellular_component | cytoplasm |
| N | 0006826 | biological_process | iron ion transport |
| N | 0006879 | biological_process | intracellular iron ion homeostasis |
| N | 0006880 | biological_process | intracellular sequestering of iron ion |
| N | 0008198 | molecular_function | ferrous iron binding |
| N | 0008199 | molecular_function | ferric iron binding |
| N | 0016491 | molecular_function | oxidoreductase activity |
| N | 0046872 | molecular_function | metal ion binding |
| O | 0004322 | molecular_function | ferroxidase activity |
| O | 0005737 | cellular_component | cytoplasm |
| O | 0006826 | biological_process | iron ion transport |
| O | 0006879 | biological_process | intracellular iron ion homeostasis |
| O | 0006880 | biological_process | intracellular sequestering of iron ion |
| O | 0008198 | molecular_function | ferrous iron binding |
| O | 0008199 | molecular_function | ferric iron binding |
| O | 0016491 | molecular_function | oxidoreductase activity |
| O | 0046872 | molecular_function | metal ion binding |
| P | 0004322 | molecular_function | ferroxidase activity |
| P | 0005737 | cellular_component | cytoplasm |
| P | 0006826 | biological_process | iron ion transport |
| P | 0006879 | biological_process | intracellular iron ion homeostasis |
| P | 0006880 | biological_process | intracellular sequestering of iron ion |
| P | 0008198 | molecular_function | ferrous iron binding |
| P | 0008199 | molecular_function | ferric iron binding |
| P | 0016491 | molecular_function | oxidoreductase activity |
| P | 0046872 | molecular_function | metal ion binding |
| Q | 0004322 | molecular_function | ferroxidase activity |
| Q | 0005737 | cellular_component | cytoplasm |
| Q | 0006826 | biological_process | iron ion transport |
| Q | 0006879 | biological_process | intracellular iron ion homeostasis |
| Q | 0006880 | biological_process | intracellular sequestering of iron ion |
| Q | 0008198 | molecular_function | ferrous iron binding |
| Q | 0008199 | molecular_function | ferric iron binding |
| Q | 0016491 | molecular_function | oxidoreductase activity |
| Q | 0046872 | molecular_function | metal ion binding |
| R | 0004322 | molecular_function | ferroxidase activity |
| R | 0005737 | cellular_component | cytoplasm |
| R | 0006826 | biological_process | iron ion transport |
| R | 0006879 | biological_process | intracellular iron ion homeostasis |
| R | 0006880 | biological_process | intracellular sequestering of iron ion |
| R | 0008198 | molecular_function | ferrous iron binding |
| R | 0008199 | molecular_function | ferric iron binding |
| R | 0016491 | molecular_function | oxidoreductase activity |
| R | 0046872 | molecular_function | metal ion binding |
| S | 0004322 | molecular_function | ferroxidase activity |
| S | 0005737 | cellular_component | cytoplasm |
| S | 0006826 | biological_process | iron ion transport |
| S | 0006879 | biological_process | intracellular iron ion homeostasis |
| S | 0006880 | biological_process | intracellular sequestering of iron ion |
| S | 0008198 | molecular_function | ferrous iron binding |
| S | 0008199 | molecular_function | ferric iron binding |
| S | 0016491 | molecular_function | oxidoreductase activity |
| S | 0046872 | molecular_function | metal ion binding |
| T | 0004322 | molecular_function | ferroxidase activity |
| T | 0005737 | cellular_component | cytoplasm |
| T | 0006826 | biological_process | iron ion transport |
| T | 0006879 | biological_process | intracellular iron ion homeostasis |
| T | 0006880 | biological_process | intracellular sequestering of iron ion |
| T | 0008198 | molecular_function | ferrous iron binding |
| T | 0008199 | molecular_function | ferric iron binding |
| T | 0016491 | molecular_function | oxidoreductase activity |
| T | 0046872 | molecular_function | metal ion binding |
| U | 0004322 | molecular_function | ferroxidase activity |
| U | 0005737 | cellular_component | cytoplasm |
| U | 0006826 | biological_process | iron ion transport |
| U | 0006879 | biological_process | intracellular iron ion homeostasis |
| U | 0006880 | biological_process | intracellular sequestering of iron ion |
| U | 0008198 | molecular_function | ferrous iron binding |
| U | 0008199 | molecular_function | ferric iron binding |
| U | 0016491 | molecular_function | oxidoreductase activity |
| U | 0046872 | molecular_function | metal ion binding |
| V | 0004322 | molecular_function | ferroxidase activity |
| V | 0005737 | cellular_component | cytoplasm |
| V | 0006826 | biological_process | iron ion transport |
| V | 0006879 | biological_process | intracellular iron ion homeostasis |
| V | 0006880 | biological_process | intracellular sequestering of iron ion |
| V | 0008198 | molecular_function | ferrous iron binding |
| V | 0008199 | molecular_function | ferric iron binding |
| V | 0016491 | molecular_function | oxidoreductase activity |
| V | 0046872 | molecular_function | metal ion binding |
| W | 0004322 | molecular_function | ferroxidase activity |
| W | 0005737 | cellular_component | cytoplasm |
| W | 0006826 | biological_process | iron ion transport |
| W | 0006879 | biological_process | intracellular iron ion homeostasis |
| W | 0006880 | biological_process | intracellular sequestering of iron ion |
| W | 0008198 | molecular_function | ferrous iron binding |
| W | 0008199 | molecular_function | ferric iron binding |
| W | 0016491 | molecular_function | oxidoreductase activity |
| W | 0046872 | molecular_function | metal ion binding |
| X | 0004322 | molecular_function | ferroxidase activity |
| X | 0005737 | cellular_component | cytoplasm |
| X | 0006826 | biological_process | iron ion transport |
| X | 0006879 | biological_process | intracellular iron ion homeostasis |
| X | 0006880 | biological_process | intracellular sequestering of iron ion |
| X | 0008198 | molecular_function | ferrous iron binding |
| X | 0008199 | molecular_function | ferric iron binding |
| X | 0016491 | molecular_function | oxidoreductase activity |
| X | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 201 |
| Chain | Residue |
| A | TYR34 |
| A | GLU49 |
| A | LYS52 |
| A | HOH411 |
| A | HOH456 |
| B | LYS67 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 202 |
| Chain | Residue |
| A | HIS45 |
| A | HOH413 |
| A | HOH455 |
| R | ASP146 |
| R | HOH395 |
| A | PHE37 |
| A | ASP38 |
| A | ALA43 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 203 |
| Chain | Residue |
| A | LYS71 |
| A | HIS124 |
| A | HOH486 |
| M | GLU135 |
| M | LYS139 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 201 |
| Chain | Residue |
| B | ASN7 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue CL B 202 |
| Chain | Residue |
| B | ASN21 |
| B | TYR25 |
| B | LYS80 |
| B | ILE81 |
| B | LYS82 |
| B | HOH446 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 203 |
| Chain | Residue |
| B | ARG39 |
| B | GLU88 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 204 |
| Chain | Residue |
| B | ASN159 |
| B | GLY160 |
| B | MET161 |
| M | ARG153 |
| M | LEU154 |
| M | GLY155 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 205 |
| Chain | Residue |
| B | ASN46 |
| B | LYS168 |
| B | HOH484 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 201 |
| Chain | Residue |
| C | TYR34 |
| C | GLU49 |
| C | LYS52 |
| D | LYS67 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue CL C 202 |
| Chain | Residue |
| C | ASN7 |
| site_id | AD2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO C 203 |
| Chain | Residue |
| C | PRO157 |
| C | GLU158 |
| C | GLY160 |
| C | HOH302 |
| C | HOH304 |
| C | HOH321 |
| C | HOH412 |
| C | HOH415 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 204 |
| Chain | Residue |
| A | ARG153 |
| C | ASP41 |
| C | GLY90 |
| C | GLU163 |
| C | HOH370 |
| C | HOH412 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 205 |
| Chain | Residue |
| C | TYR68 |
| C | LYS71 |
| C | HIS124 |
| C | PHE128 |
| C | HOH333 |
| F | GLU135 |
| site_id | AD5 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 D 201 |
| Chain | Residue |
| D | LEU165 |
| D | HIS169 |
| F | LEU165 |
| F | HIS169 |
| N | LEU165 |
| N | HIS169 |
| P | LEU165 |
| P | HIS169 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 D 202 |
| Chain | Residue |
| A | HOH401 |
| A | HOH416 |
| D | GLN6 |
| D | ASN7 |
| D | HOH321 |
| D | HOH366 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue CL D 203 |
| Chain | Residue |
| D | GLU163 |
| D | HOH395 |
| F | ARG153 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue CL D 204 |
| Chain | Residue |
| D | TYR34 |
| D | GLU49 |
| site_id | AD9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO D 205 |
| Chain | Residue |
| D | ASP146 |
| D | HOH320 |
| D | HOH383 |
| D | HOH443 |
| N | ASP38 |
| N | ALA43 |
| N | HIS45 |
| site_id | AE1 |
| Number of Residues | 1 |
| Details | binding site for residue CL M 201 |
| Chain | Residue |
| M | ASN7 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO M 202 |
| Chain | Residue |
| M | PRO157 |
| M | GLU158 |
| M | HOH301 |
| M | HOH303 |
| M | HOH408 |
| W | CL203 |
| site_id | AE3 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 N 201 |
| Chain | Residue |
| N | HOH469 |
| W | HOH383 |
| W | HOH396 |
| N | ARG5 |
| N | GLN6 |
| N | ASN7 |
| N | HOH348 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 N 202 |
| Chain | Residue |
| M | LYS67 |
| N | TYR34 |
| N | GLU49 |
| N | LYS52 |
| N | HOH457 |
| N | HOH473 |
| site_id | AE5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO N 203 |
| Chain | Residue |
| N | LYS71 |
| N | HIS124 |
| N | HOH453 |
| W | GLU135 |
| W | VAL138 |
| W | LYS139 |
| site_id | AE6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO N 204 |
| Chain | Residue |
| N | THR118 |
| N | PRO123 |
| W | HOH402 |
| site_id | AE7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO N 205 |
| Chain | Residue |
| N | VAL1 |
| N | SER2 |
| N | ARG5 |
| N | GLY73 |
| N | ARG75 |
| N | HOH333 |
| N | HOH402 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 O 201 |
| Chain | Residue |
| O | TYR34 |
| O | GLU49 |
| O | LYS52 |
| P | LYS67 |
| site_id | AE9 |
| Number of Residues | 2 |
| Details | binding site for residue CL O 202 |
| Chain | Residue |
| O | GLU135 |
| W | HIS124 |
| site_id | AF1 |
| Number of Residues | 2 |
| Details | binding site for residue CL O 203 |
| Chain | Residue |
| O | ASN7 |
| O | HOH482 |
| site_id | AF2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO O 204 |
| Chain | Residue |
| O | PRO157 |
| O | GLU158 |
| O | HOH303 |
| O | HOH305 |
| O | HOH346 |
| O | HOH408 |
| site_id | AF3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 P 201 |
| Chain | Residue |
| O | LYS67 |
| P | TYR34 |
| P | HIS45 |
| P | GLU49 |
| P | LYS52 |
| site_id | AF4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO P 202 |
| Chain | Residue |
| P | LYS64 |
| P | LYS67 |
| P | TYR68 |
| P | LYS71 |
| P | PHE128 |
| P | HOH430 |
| site_id | AF5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO P 203 |
| Chain | Residue |
| P | ASN46 |
| P | LYS168 |
| site_id | AF6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO P 204 |
| Chain | Residue |
| N | ARG153 |
| P | VAL42 |
| P | GLY90 |
| P | GLU163 |
| P | HOH378 |
| P | HOH432 |
| site_id | AF7 |
| Number of Residues | 4 |
| Details | binding site for residue CL S 201 |
| Chain | Residue |
| G | GLY160 |
| G | GLU163 |
| G | EDO205 |
| S | ARG153 |
| site_id | AF8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO S 202 |
| Chain | Residue |
| S | VAL1 |
| S | SER2 |
| S | ARG5 |
| S | GLY73 |
| S | ARG75 |
| S | HOH346 |
| site_id | AF9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO S 203 |
| Chain | Residue |
| F | LYS71 |
| F | HIS124 |
| S | GLU135 |
| S | VAL138 |
| S | LYS139 |
| S | HOH487 |
| site_id | AG1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO S 204 |
| Chain | Residue |
| S | ASN46 |
| S | LYS168 |
| S | LYS172 |
| S | HOH476 |
| S | HOH499 |
| site_id | AG2 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 T 201 |
| Chain | Residue |
| T | ARG39 |
| T | GLU88 |
| site_id | AG3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 T 202 |
| Chain | Residue |
| J | HOH390 |
| J | HOH397 |
| T | ARG5 |
| T | GLN6 |
| T | ASN7 |
| T | HOH333 |
| site_id | AG4 |
| Number of Residues | 9 |
| Details | binding site for residue CL T 203 |
| Chain | Residue |
| T | GLY155 |
| T | LEU156 |
| T | PRO157 |
| T | GLU158 |
| X | GLY155 |
| X | LEU156 |
| X | PRO157 |
| X | GLU158 |
| X | HOH304 |
| site_id | AG5 |
| Number of Residues | 1 |
| Details | binding site for residue CL T 204 |
| Chain | Residue |
| T | GLU49 |
| site_id | AG6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO T 205 |
| Chain | Residue |
| T | VAL1 |
| T | SER2 |
| T | ARG5 |
| T | GLY73 |
| T | ARG75 |
| T | HOH359 |
| T | HOH479 |
| site_id | AG7 |
| Number of Residues | 8 |
| Details | binding site for residue CL E 201 |
| Chain | Residue |
| E | GLY155 |
| E | GLY155 |
| E | LEU156 |
| E | LEU156 |
| E | PRO157 |
| E | PRO157 |
| E | GLU158 |
| E | GLU158 |
| site_id | AG8 |
| Number of Residues | 3 |
| Details | binding site for residue CL E 202 |
| Chain | Residue |
| E | MET161 |
| G | ARG153 |
| G | LEU154 |
| site_id | AG9 |
| Number of Residues | 1 |
| Details | binding site for residue CL E 203 |
| Chain | Residue |
| E | ASN7 |
| site_id | AH1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO E 204 |
| Chain | Residue |
| E | LYS64 |
| E | PHE128 |
| E | HOH428 |
| E | HOH504 |
| site_id | AH2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO E 205 |
| Chain | Residue |
| E | ASN46 |
| E | HOH413 |
| site_id | AH3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 F 201 |
| Chain | Residue |
| F | GLN6 |
| F | ASN7 |
| F | HOH341 |
| F | HOH356 |
| F | HOH370 |
| S | HOH390 |
| site_id | AH4 |
| Number of Residues | 2 |
| Details | binding site for residue CL F 202 |
| Chain | Residue |
| F | HOH520 |
| G | HOH321 |
| site_id | AH5 |
| Number of Residues | 1 |
| Details | binding site for residue CL F 203 |
| Chain | Residue |
| F | GLU49 |
| site_id | AH6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO F 204 |
| Chain | Residue |
| F | VAL121 |
| F | PRO123 |
| F | HOH400 |
| F | HOH497 |
| S | HIS114 |
| site_id | AH7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO F 205 |
| Chain | Residue |
| F | GLY73 |
| F | ARG75 |
| F | HOH336 |
| F | HOH360 |
| F | HOH368 |
| F | HOH508 |
| site_id | AH8 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 G 201 |
| Chain | Residue |
| G | GLN6 |
| G | ASN7 |
| G | HOH354 |
| P | HOH336 |
| P | HOH368 |
| site_id | AH9 |
| Number of Residues | 6 |
| Details | binding site for residue CL G 202 |
| Chain | Residue |
| G | ALA43 |
| G | HOH333 |
| G | HOH481 |
| S | ASP146 |
| S | HOH420 |
| S | HOH524 |
| site_id | AI1 |
| Number of Residues | 5 |
| Details | binding site for residue CL G 203 |
| Chain | Residue |
| F | TYR28 |
| G | ASN21 |
| G | LEU78 |
| G | GLN79 |
| G | HOH314 |
| site_id | AI2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO G 205 |
| Chain | Residue |
| G | PRO157 |
| G | GLU158 |
| G | GLY160 |
| G | HOH303 |
| G | HOH304 |
| G | HOH399 |
| G | HOH433 |
| S | CL201 |
| site_id | AI3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO G 206 |
| Chain | Residue |
| G | ASN46 |
| G | LYS168 |
| G | HOH410 |
| G | HOH431 |
| site_id | AI4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO G 207 |
| Chain | Residue |
| G | GLU85 |
| G | ARG86 |
| G | ALA98 |
| G | HOH322 |
| G | HOH507 |
| site_id | AI5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO G 208 |
| Chain | Residue |
| G | HIS9 |
| G | SER10 |
| G | HOH453 |
| site_id | AI6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO G 209 |
| Chain | Residue |
| G | ARG86 |
| G | ASP87 |
| G | GLU88 |
| site_id | AI7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO G 210 |
| Chain | Residue |
| G | GLY155 |
| G | GLU158 |
| G | ASN159 |
| G | HOH301 |
| J | HOH307 |
| site_id | AI8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO G 211 |
| Chain | Residue |
| G | VAL1 |
| G | SER2 |
| G | ARG5 |
| G | GLY73 |
| G | ARG75 |
| G | HOH335 |
| G | HOH482 |
| site_id | AI9 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 H 201 |
| Chain | Residue |
| H | TYR34 |
| H | GLU49 |
| H | LYS52 |
| H | HOH442 |
| H | HOH461 |
| J | LYS67 |
| site_id | AJ1 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 H 202 |
| Chain | Residue |
| E | HOH378 |
| E | HOH379 |
| H | ARG5 |
| H | GLN6 |
| H | ASN7 |
| H | HOH317 |
| H | HOH472 |
| site_id | AJ2 |
| Number of Residues | 3 |
| Details | binding site for residue CL H 203 |
| Chain | Residue |
| H | ALA43 |
| H | HOH491 |
| Q | ASP146 |
| site_id | AJ3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 I 201 |
| Chain | Residue |
| E | LYS67 |
| I | TYR34 |
| I | GLU49 |
| I | LYS52 |
| I | HOH433 |
| I | HOH507 |
| site_id | AJ4 |
| Number of Residues | 1 |
| Details | binding site for residue CL I 202 |
| Chain | Residue |
| I | ASN7 |
| site_id | AJ5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO I 203 |
| Chain | Residue |
| I | VAL1 |
| I | SER2 |
| I | ARG5 |
| I | GLY73 |
| I | ARG75 |
| I | HOH380 |
| I | HOH515 |
| site_id | AJ6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO I 204 |
| Chain | Residue |
| G | HIS114 |
| G | THR118 |
| G | HOH330 |
| I | CYS126 |
| I | HOH444 |
| site_id | AJ7 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 J 201 |
| Chain | Residue |
| E | LEU165 |
| E | HIS169 |
| G | LEU165 |
| G | HIS169 |
| J | LEU165 |
| J | HIS169 |
| S | LEU165 |
| S | HIS169 |
| site_id | AJ8 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 J 202 |
| Chain | Residue |
| J | GLN6 |
| J | ASN7 |
| J | HOH346 |
| Q | HOH337 |
| Q | HOH368 |
| site_id | AJ9 |
| Number of Residues | 4 |
| Details | binding site for residue CL J 203 |
| Chain | Residue |
| J | GLU135 |
| T | LYS71 |
| T | HIS124 |
| T | HOH431 |
| site_id | AK1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO J 204 |
| Chain | Residue |
| J | ASP127 |
| J | HOH467 |
| Q | GLU130 |
| Q | SER131 |
| Q | GLU135 |
| site_id | AK2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO J 205 |
| Chain | Residue |
| J | LYS142 |
| J | ASP146 |
| J | HOH424 |
| J | HOH483 |
| S | ASP38 |
| S | HOH333 |
| T | LYS71 |
| site_id | AK3 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 K 201 |
| Chain | Residue |
| H | LEU165 |
| H | HIS169 |
| K | LEU165 |
| K | HIS169 |
| K | HOH401 |
| Q | LEU165 |
| Q | HIS169 |
| U | LEU165 |
| U | HIS169 |
| site_id | AK4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 K 202 |
| Chain | Residue |
| K | TYR34 |
| K | GLU49 |
| K | LYS52 |
| L | LYS67 |
| site_id | AK5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO K 203 |
| Chain | Residue |
| K | LYS64 |
| K | LYS67 |
| K | TYR68 |
| K | LYS71 |
| K | PHE128 |
| K | HOH400 |
| site_id | AK6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO K 204 |
| Chain | Residue |
| H | ARG153 |
| K | ASP41 |
| K | GLY90 |
| K | GLU163 |
| site_id | AK7 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 L 201 |
| Chain | Residue |
| I | LEU165 |
| I | HIS169 |
| L | LEU165 |
| L | HIS169 |
| O | LEU165 |
| O | HIS169 |
| X | LEU165 |
| X | HIS169 |
| site_id | AK8 |
| Number of Residues | 5 |
| Details | binding site for residue CL L 202 |
| Chain | Residue |
| A | HOH312 |
| L | LEU93 |
| L | GLN97 |
| L | HOH318 |
| L | HOH443 |
| site_id | AK9 |
| Number of Residues | 1 |
| Details | binding site for residue CL L 203 |
| Chain | Residue |
| L | GLU49 |
| site_id | AL1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO L 204 |
| Chain | Residue |
| L | ASP41 |
| L | VAL42 |
| L | GLY90 |
| L | GLU163 |
| L | HOH501 |
| X | ARG153 |
| site_id | AL2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO L 205 |
| Chain | Residue |
| K | ARG75 |
| K | VAL76 |
| L | ARG39 |
| L | ASP87 |
| L | HOH416 |
| L | HOH489 |
| site_id | AL3 |
| Number of Residues | 1 |
| Details | binding site for residue CL Q 201 |
| Chain | Residue |
| Q | ASN7 |
| site_id | AL4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO Q 202 |
| Chain | Residue |
| Q | ALA43 |
| Q | HOH309 |
| Q | HOH425 |
| U | ASP146 |
| U | HOH442 |
| site_id | AL5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO Q 203 |
| Chain | Residue |
| Q | ASP41 |
| Q | HOH355 |
| U | THR149 |
| site_id | AL6 |
| Number of Residues | 4 |
| Details | binding site for residue ACT Q 204 |
| Chain | Residue |
| Q | TYR34 |
| Q | GLU49 |
| Q | LYS52 |
| R | LYS67 |
| site_id | AL7 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 R 201 |
| Chain | Residue |
| A | LEU165 |
| A | HIS169 |
| C | LEU165 |
| C | HIS169 |
| R | LEU165 |
| R | HIS169 |
| R | HOH494 |
| T | LEU165 |
| T | HIS169 |
| site_id | AL8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 R 202 |
| Chain | Residue |
| Q | LYS67 |
| R | TYR34 |
| R | GLU49 |
| site_id | AL9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO R 203 |
| Chain | Residue |
| R | ASP41 |
| R | VAL42 |
| R | GLY90 |
| R | GLU163 |
| R | HOH502 |
| T | ARG153 |
| site_id | AM1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO R 204 |
| Chain | Residue |
| R | ASN7 |
| R | HOH404 |
| R | HOH440 |
| U | HOH471 |
| U | HOH497 |
| site_id | AM2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO R 205 |
| Chain | Residue |
| B | VAL121 |
| R | HIS114 |
| R | HOH339 |
| R | HOH418 |
| R | HOH434 |
| site_id | AM3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO R 206 |
| Chain | Residue |
| R | VAL1 |
| R | SER2 |
| R | ARG5 |
| R | GLY73 |
| R | ARG75 |
| R | HOH402 |
| site_id | AM4 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 U 201 |
| Chain | Residue |
| B | HOH354 |
| U | ARG5 |
| U | GLN6 |
| U | ASN7 |
| U | HOH322 |
| U | HOH354 |
| U | HOH397 |
| U | HOH480 |
| site_id | AM5 |
| Number of Residues | 2 |
| Details | binding site for residue CL U 202 |
| Chain | Residue |
| U | ALA98 |
| U | HOH356 |
| site_id | AM6 |
| Number of Residues | 1 |
| Details | binding site for residue CL U 203 |
| Chain | Residue |
| U | GLU49 |
| site_id | AM7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO U 204 |
| Chain | Residue |
| U | LYS83 |
| U | HOH389 |
| site_id | AM8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO V 201 |
| Chain | Residue |
| V | ASP146 |
| V | HOH342 |
| V | HOH413 |
| W | ALA43 |
| W | HIS45 |
| site_id | AM9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO V 202 |
| Chain | Residue |
| K | HOH377 |
| V | ARG5 |
| V | GLN6 |
| V | ASN7 |
| V | HOH389 |
| V | HOH452 |
| site_id | AN1 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 W 201 |
| Chain | Residue |
| B | LEU165 |
| B | HIS169 |
| M | LEU165 |
| M | HIS169 |
| V | LEU165 |
| V | HIS169 |
| W | LEU165 |
| W | HIS169 |
| site_id | AN2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 W 202 |
| Chain | Residue |
| O | HOH394 |
| W | GLN6 |
| W | ASN7 |
| W | HOH367 |
| W | HOH469 |
| site_id | AN3 |
| Number of Residues | 4 |
| Details | binding site for residue CL W 203 |
| Chain | Residue |
| M | GLY160 |
| M | GLU163 |
| M | EDO202 |
| W | ARG153 |
| site_id | AN4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO W 204 |
| Chain | Residue |
| W | VAL1 |
| W | SER2 |
| W | ARG5 |
| W | GLY73 |
| W | ARG75 |
| W | HOH342 |
| site_id | AN5 |
| Number of Residues | 1 |
| Details | binding site for residue CL X 201 |
| Chain | Residue |
| X | ARG39 |
| site_id | AN6 |
| Number of Residues | 1 |
| Details | binding site for residue CL X 202 |
| Chain | Residue |
| X | ASN7 |
| site_id | AN7 |
| Number of Residues | 2 |
| Details | binding site for residue CL X 203 |
| Chain | Residue |
| X | TYR34 |
| X | GLU49 |
| site_id | AN8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO X 204 |
| Chain | Residue |
| O | ARG153 |
| X | ASP41 |
| X | GLY90 |
| X | GLU163 |
| X | HOH438 |
| site_id | AN9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO X 205 |
| Chain | Residue |
| X | ARG86 |
| X | ASP87 |
| X | GLU88 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 144 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU23 | |
| B | GLU103 | |
| K | GLU103 | |
| K | GLN137 | |
| K | ASP140 | |
| L | GLU23 | |
| L | GLU58 | |
| L | HIS61 | |
| L | GLU103 | |
| L | GLN137 | |
| L | ASP140 | |
| Q | GLU23 | |
| B | GLN137 | |
| Q | GLU58 | |
| Q | HIS61 | |
| Q | GLU103 | |
| Q | GLN137 | |
| Q | ASP140 | |
| R | GLU23 | |
| R | GLU58 | |
| R | HIS61 | |
| R | GLU103 | |
| R | GLN137 | |
| B | ASP140 | |
| R | ASP140 | |
| U | GLU23 | |
| U | GLU58 | |
| U | HIS61 | |
| U | GLU103 | |
| U | GLN137 | |
| U | ASP140 | |
| V | GLU23 | |
| V | GLU58 | |
| V | HIS61 | |
| C | GLU23 | |
| V | GLU103 | |
| V | GLN137 | |
| V | ASP140 | |
| W | GLU23 | |
| W | GLU58 | |
| W | HIS61 | |
| W | GLU103 | |
| W | GLN137 | |
| W | ASP140 | |
| X | GLU23 | |
| C | GLU58 | |
| X | GLU58 | |
| X | HIS61 | |
| X | GLU103 | |
| X | GLN137 | |
| X | ASP140 | |
| C | HIS61 | |
| C | GLU103 | |
| C | GLN137 | |
| C | ASP140 | |
| D | GLU23 | |
| A | GLU58 | |
| D | GLU58 | |
| D | HIS61 | |
| D | GLU103 | |
| D | GLN137 | |
| D | ASP140 | |
| M | GLU23 | |
| M | GLU58 | |
| M | HIS61 | |
| M | GLU103 | |
| M | GLN137 | |
| A | HIS61 | |
| M | ASP140 | |
| N | GLU23 | |
| N | GLU58 | |
| N | HIS61 | |
| N | GLU103 | |
| N | GLN137 | |
| N | ASP140 | |
| O | GLU23 | |
| O | GLU58 | |
| O | HIS61 | |
| A | GLU103 | |
| O | GLU103 | |
| O | GLN137 | |
| O | ASP140 | |
| P | GLU23 | |
| P | GLU58 | |
| P | HIS61 | |
| P | GLU103 | |
| P | GLN137 | |
| P | ASP140 | |
| S | GLU23 | |
| A | GLN137 | |
| S | GLU58 | |
| S | HIS61 | |
| S | GLU103 | |
| S | GLN137 | |
| S | ASP140 | |
| T | GLU23 | |
| T | GLU58 | |
| T | HIS61 | |
| T | GLU103 | |
| T | GLN137 | |
| A | ASP140 | |
| T | ASP140 | |
| E | GLU23 | |
| E | GLU58 | |
| E | HIS61 | |
| E | GLU103 | |
| E | GLN137 | |
| E | ASP140 | |
| F | GLU23 | |
| F | GLU58 | |
| F | HIS61 | |
| B | GLU23 | |
| F | GLU103 | |
| F | GLN137 | |
| F | ASP140 | |
| G | GLU23 | |
| G | GLU58 | |
| G | HIS61 | |
| G | GLU103 | |
| G | GLN137 | |
| G | ASP140 | |
| H | GLU23 | |
| B | GLU58 | |
| H | GLU58 | |
| H | HIS61 | |
| H | GLU103 | |
| H | GLN137 | |
| H | ASP140 | |
| I | GLU23 | |
| I | GLU58 | |
| I | HIS61 | |
| I | GLU103 | |
| I | GLN137 | |
| B | HIS61 | |
| I | ASP140 | |
| J | GLU23 | |
| J | GLU58 | |
| J | HIS61 | |
| J | GLU103 | |
| J | GLN137 | |
| J | ASP140 | |
| K | GLU23 | |
| K | GLU58 | |
| K | HIS61 |
