Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4OYJ

Structure of the apo HOIP PUB domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004842	molecular_function	ubiquitin-protein transferase activity
A	0071797	cellular_component	LUBAC complex
B	0004842	molecular_function	ubiquitin-protein transferase activity
B	0071797	cellular_component	LUBAC complex
C	0004842	molecular_function	ubiquitin-protein transferase activity
C	0071797	cellular_component	LUBAC complex
D	0004842	molecular_function	ubiquitin-protein transferase activity
D	0071797	cellular_component	LUBAC complex
E	0004842	molecular_function	ubiquitin-protein transferase activity
E	0071797	cellular_component	LUBAC complex
F	0004842	molecular_function	ubiquitin-protein transferase activity
F	0071797	cellular_component	LUBAC complex
G	0004842	molecular_function	ubiquitin-protein transferase activity
G	0071797	cellular_component	LUBAC complex
H	0004842	molecular_function	ubiquitin-protein transferase activity
H	0071797	cellular_component	LUBAC complex
I	0004842	molecular_function	ubiquitin-protein transferase activity
I	0071797	cellular_component	LUBAC complex
J	0004842	molecular_function	ubiquitin-protein transferase activity
J	0071797	cellular_component	LUBAC complex
K	0004842	molecular_function	ubiquitin-protein transferase activity
K	0071797	cellular_component	LUBAC complex
L	0004842	molecular_function	ubiquitin-protein transferase activity
L	0071797	cellular_component	LUBAC complex
M	0004842	molecular_function	ubiquitin-protein transferase activity
M	0071797	cellular_component	LUBAC complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue SO4 A 201

Chain	Residue
A	ARG120
M	ARG55

site_id	AC2
Number of Residues	4
Details	binding site for residue SO4 A 202

Chain	Residue
A	PRO169
A	ARG170
A	GLN171
A	GLN172

site_id	AC3
Number of Residues	3
Details	binding site for residue SO4 A 203

Chain	Residue
A	ARG106
E	ALA45
E	ALA54

site_id	AC4
Number of Residues	3
Details	binding site for residue SO4 B 201

Chain	Residue
A	SER30
A	LEU31
B	ARG22

site_id	AC5
Number of Residues	3
Details	binding site for residue SO4 B 202

Chain	Residue
B	ARG116
B	ARG120
E	ARG55

site_id	AC6
Number of Residues	4
Details	binding site for residue SO4 B 203

Chain	Residue
B	ARG55
E	ARG116
E	ASP117
E	ARG120

site_id	AC7
Number of Residues	5
Details	binding site for residue SO4 B 204

Chain	Residue
B	ALA61
B	HIS62
B	GLY63
E	HIS62
E	GLY63

site_id	AC8
Number of Residues	3
Details	binding site for residue SO4 C 201

Chain	Residue
C	ARG116
C	ARG120
J	ARG55

site_id	AC9
Number of Residues	6
Details	binding site for residue SO4 C 202

Chain	Residue
C	ALA61
C	HIS62
C	GLY63
J	ALA61
J	HIS62
J	GLY63

site_id	AD1
Number of Residues	3
Details	binding site for residue SO4 C 203

Chain	Residue
C	GLN138
C	GLU139
C	GLU140

site_id	AD2
Number of Residues	4
Details	binding site for residue SO4 C 204

Chain	Residue
C	ARG170
C	GLN172
C	ALA173
C	HOH301

site_id	AD3
Number of Residues	3
Details	binding site for residue SO4 D 201

Chain	Residue
D	ARG14
D	LEU49
D	GLN50

site_id	AD4
Number of Residues	2
Details	binding site for residue SO4 D 202

Chain	Residue
D	ARG91
D	TRP95

site_id	AD5
Number of Residues	5
Details	binding site for residue SO4 D 203

Chain	Residue
D	ASP142
D	GLU143
D	HIS144
D	GLN145
F	ARG22

site_id	AD6
Number of Residues	3
Details	binding site for residue SO4 D 204

Chain	Residue
D	ARG22
D	ARG23
E	LEU31

site_id	AD7
Number of Residues	3
Details	binding site for residue SO4 E 201

Chain	Residue
D	PRO89
E	ARG35
E	ARG170

site_id	AD8
Number of Residues	5
Details	binding site for residue SO4 F 201

Chain	Residue
D	GLU139
D	GLU140
F	GLU15
F	HIS144
F	THR148

site_id	AD9
Number of Residues	3
Details	binding site for residue SO4 F 202

Chain	Residue
E	SER19
F	ARG35
F	ARG170

site_id	AE1
Number of Residues	3
Details	binding site for residue SO4 F 203

Chain	Residue
F	ARG55
F	ARG116
F	ARG120

site_id	AE2
Number of Residues	4
Details	binding site for residue SO4 G 201

Chain	Residue
G	ARG14
G	LEU49
G	GLN50
G	THR148

site_id	AE3
Number of Residues	2
Details	binding site for residue SO4 G 202

Chain	Residue
G	ARG91
G	TRP95

site_id	AE4
Number of Residues	3
Details	binding site for residue SO4 H 201

Chain	Residue
G	ARG116
G	ARG120
H	ARG55

site_id	AE5
Number of Residues	2
Details	binding site for residue SO4 H 202

Chain	Residue
H	HIS62
H	GLY63

site_id	AE6
Number of Residues	6
Details	binding site for residue SO4 I 201

Chain	Residue
I	ALA61
I	HIS62
I	GLY63
K	ALA61
K	HIS62
K	GLY63

site_id	AE7
Number of Residues	3
Details	binding site for residue SO4 I 202

Chain	Residue
I	ARG55
K	ARG116
K	ARG120

site_id	AE8
Number of Residues	2
Details	binding site for residue SO4 I 203

Chain	Residue
I	TRP95
I	ARG96

site_id	AE9
Number of Residues	3
Details	binding site for residue SO4 J 201

Chain	Residue
J	GLN138
J	GLU139
J	GLU140

site_id	AF1
Number of Residues	3
Details	binding site for residue SO4 J 202

Chain	Residue
C	ARG55
J	ARG116
J	ARG120

site_id	AF2
Number of Residues	4
Details	binding site for residue SO4 M 201

Chain	Residue
A	ARG55
M	ARG116
M	ASP117
M	ARG120

site_id	AF3
Number of Residues	6
Details	binding site for residue SO4 M 202

Chain	Residue
A	ALA61
A	HIS62
A	GLY63
M	ALA61
M	HIS62
M	GLY63

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	923
Details	Domain: {"description":"PUB","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)