Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4OYE

Crystal structure of GltPh R397A in apo

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005283	molecular_function	amino acid:sodium symporter activity
A	0005886	cellular_component	plasma membrane
A	0006835	biological_process	dicarboxylic acid transport
A	0006865	biological_process	amino acid transport
A	0015108	molecular_function	chloride transmembrane transporter activity
A	0015183	molecular_function	L-aspartate transmembrane transporter activity
A	0015293	molecular_function	symporter activity
A	0015501	molecular_function	glutamate:sodium symporter activity
A	0016020	cellular_component	membrane
A	0035725	biological_process	sodium ion transmembrane transport
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
A	0070207	biological_process	protein homotrimerization
A	0070778	biological_process	L-aspartate transmembrane transport
A	0140009	biological_process	L-aspartate import across plasma membrane
A	1902476	biological_process	chloride transmembrane transport
B	0005283	molecular_function	amino acid:sodium symporter activity
B	0005886	cellular_component	plasma membrane
B	0006835	biological_process	dicarboxylic acid transport
B	0006865	biological_process	amino acid transport
B	0015108	molecular_function	chloride transmembrane transporter activity
B	0015183	molecular_function	L-aspartate transmembrane transporter activity
B	0015293	molecular_function	symporter activity
B	0015501	molecular_function	glutamate:sodium symporter activity
B	0016020	cellular_component	membrane
B	0035725	biological_process	sodium ion transmembrane transport
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
B	0070207	biological_process	protein homotrimerization
B	0070778	biological_process	L-aspartate transmembrane transport
B	0140009	biological_process	L-aspartate import across plasma membrane
B	1902476	biological_process	chloride transmembrane transport
C	0005283	molecular_function	amino acid:sodium symporter activity
C	0005886	cellular_component	plasma membrane
C	0006835	biological_process	dicarboxylic acid transport
C	0006865	biological_process	amino acid transport
C	0015108	molecular_function	chloride transmembrane transporter activity
C	0015183	molecular_function	L-aspartate transmembrane transporter activity
C	0015293	molecular_function	symporter activity
C	0015501	molecular_function	glutamate:sodium symporter activity
C	0016020	cellular_component	membrane
C	0035725	biological_process	sodium ion transmembrane transport
C	0042802	molecular_function	identical protein binding
C	0046872	molecular_function	metal ion binding
C	0070207	biological_process	protein homotrimerization
C	0070778	biological_process	L-aspartate transmembrane transport
C	0140009	biological_process	L-aspartate import across plasma membrane
C	1902476	biological_process	chloride transmembrane transport
D	0005283	molecular_function	amino acid:sodium symporter activity
D	0005886	cellular_component	plasma membrane
D	0006835	biological_process	dicarboxylic acid transport
D	0006865	biological_process	amino acid transport
D	0015108	molecular_function	chloride transmembrane transporter activity
D	0015183	molecular_function	L-aspartate transmembrane transporter activity
D	0015293	molecular_function	symporter activity
D	0015501	molecular_function	glutamate:sodium symporter activity
D	0016020	cellular_component	membrane
D	0035725	biological_process	sodium ion transmembrane transport
D	0042802	molecular_function	identical protein binding
D	0046872	molecular_function	metal ion binding
D	0070207	biological_process	protein homotrimerization
D	0070778	biological_process	L-aspartate transmembrane transport
D	0140009	biological_process	L-aspartate import across plasma membrane
D	1902476	biological_process	chloride transmembrane transport
E	0005283	molecular_function	amino acid:sodium symporter activity
E	0005886	cellular_component	plasma membrane
E	0006835	biological_process	dicarboxylic acid transport
E	0006865	biological_process	amino acid transport
E	0015108	molecular_function	chloride transmembrane transporter activity
E	0015183	molecular_function	L-aspartate transmembrane transporter activity
E	0015293	molecular_function	symporter activity
E	0015501	molecular_function	glutamate:sodium symporter activity
E	0016020	cellular_component	membrane
E	0035725	biological_process	sodium ion transmembrane transport
E	0042802	molecular_function	identical protein binding
E	0046872	molecular_function	metal ion binding
E	0070207	biological_process	protein homotrimerization
E	0070778	biological_process	L-aspartate transmembrane transport
E	0140009	biological_process	L-aspartate import across plasma membrane
E	1902476	biological_process	chloride transmembrane transport
F	0005283	molecular_function	amino acid:sodium symporter activity
F	0005886	cellular_component	plasma membrane
F	0006835	biological_process	dicarboxylic acid transport
F	0006865	biological_process	amino acid transport
F	0015108	molecular_function	chloride transmembrane transporter activity
F	0015183	molecular_function	L-aspartate transmembrane transporter activity
F	0015293	molecular_function	symporter activity
F	0015501	molecular_function	glutamate:sodium symporter activity
F	0016020	cellular_component	membrane
F	0035725	biological_process	sodium ion transmembrane transport
F	0042802	molecular_function	identical protein binding
F	0046872	molecular_function	metal ion binding
F	0070207	biological_process	protein homotrimerization
F	0070778	biological_process	L-aspartate transmembrane transport
F	0140009	biological_process	L-aspartate import across plasma membrane
F	1902476	biological_process	chloride transmembrane transport
G	0005283	molecular_function	amino acid:sodium symporter activity
G	0005886	cellular_component	plasma membrane
G	0006835	biological_process	dicarboxylic acid transport
G	0006865	biological_process	amino acid transport
G	0015108	molecular_function	chloride transmembrane transporter activity
G	0015183	molecular_function	L-aspartate transmembrane transporter activity
G	0015293	molecular_function	symporter activity
G	0015501	molecular_function	glutamate:sodium symporter activity
G	0016020	cellular_component	membrane
G	0035725	biological_process	sodium ion transmembrane transport
G	0042802	molecular_function	identical protein binding
G	0046872	molecular_function	metal ion binding
G	0070207	biological_process	protein homotrimerization
G	0070778	biological_process	L-aspartate transmembrane transport
G	0140009	biological_process	L-aspartate import across plasma membrane
G	1902476	biological_process	chloride transmembrane transport
H	0005283	molecular_function	amino acid:sodium symporter activity
H	0005886	cellular_component	plasma membrane
H	0006835	biological_process	dicarboxylic acid transport
H	0006865	biological_process	amino acid transport
H	0015108	molecular_function	chloride transmembrane transporter activity
H	0015183	molecular_function	L-aspartate transmembrane transporter activity
H	0015293	molecular_function	symporter activity
H	0015501	molecular_function	glutamate:sodium symporter activity
H	0016020	cellular_component	membrane
H	0035725	biological_process	sodium ion transmembrane transport
H	0042802	molecular_function	identical protein binding
H	0046872	molecular_function	metal ion binding
H	0070207	biological_process	protein homotrimerization
H	0070778	biological_process	L-aspartate transmembrane transport
H	0140009	biological_process	L-aspartate import across plasma membrane
H	1902476	biological_process	chloride transmembrane transport
I	0005283	molecular_function	amino acid:sodium symporter activity
I	0005886	cellular_component	plasma membrane
I	0006835	biological_process	dicarboxylic acid transport
I	0006865	biological_process	amino acid transport
I	0015108	molecular_function	chloride transmembrane transporter activity
I	0015183	molecular_function	L-aspartate transmembrane transporter activity
I	0015293	molecular_function	symporter activity
I	0015501	molecular_function	glutamate:sodium symporter activity
I	0016020	cellular_component	membrane
I	0035725	biological_process	sodium ion transmembrane transport
I	0042802	molecular_function	identical protein binding
I	0046872	molecular_function	metal ion binding
I	0070207	biological_process	protein homotrimerization
I	0070778	biological_process	L-aspartate transmembrane transport
I	0140009	biological_process	L-aspartate import across plasma membrane
I	1902476	biological_process	chloride transmembrane transport
J	0005283	molecular_function	amino acid:sodium symporter activity
J	0005886	cellular_component	plasma membrane
J	0006835	biological_process	dicarboxylic acid transport
J	0006865	biological_process	amino acid transport
J	0015108	molecular_function	chloride transmembrane transporter activity
J	0015183	molecular_function	L-aspartate transmembrane transporter activity
J	0015293	molecular_function	symporter activity
J	0015501	molecular_function	glutamate:sodium symporter activity
J	0016020	cellular_component	membrane
J	0035725	biological_process	sodium ion transmembrane transport
J	0042802	molecular_function	identical protein binding
J	0046872	molecular_function	metal ion binding
J	0070207	biological_process	protein homotrimerization
J	0070778	biological_process	L-aspartate transmembrane transport
J	0140009	biological_process	L-aspartate import across plasma membrane
J	1902476	biological_process	chloride transmembrane transport
K	0005283	molecular_function	amino acid:sodium symporter activity
K	0005886	cellular_component	plasma membrane
K	0006835	biological_process	dicarboxylic acid transport
K	0006865	biological_process	amino acid transport
K	0015108	molecular_function	chloride transmembrane transporter activity
K	0015183	molecular_function	L-aspartate transmembrane transporter activity
K	0015293	molecular_function	symporter activity
K	0015501	molecular_function	glutamate:sodium symporter activity
K	0016020	cellular_component	membrane
K	0035725	biological_process	sodium ion transmembrane transport
K	0042802	molecular_function	identical protein binding
K	0046872	molecular_function	metal ion binding
K	0070207	biological_process	protein homotrimerization
K	0070778	biological_process	L-aspartate transmembrane transport
K	0140009	biological_process	L-aspartate import across plasma membrane
K	1902476	biological_process	chloride transmembrane transport
L	0005283	molecular_function	amino acid:sodium symporter activity
L	0005886	cellular_component	plasma membrane
L	0006835	biological_process	dicarboxylic acid transport
L	0006865	biological_process	amino acid transport
L	0015108	molecular_function	chloride transmembrane transporter activity
L	0015183	molecular_function	L-aspartate transmembrane transporter activity
L	0015293	molecular_function	symporter activity
L	0015501	molecular_function	glutamate:sodium symporter activity
L	0016020	cellular_component	membrane
L	0035725	biological_process	sodium ion transmembrane transport
L	0042802	molecular_function	identical protein binding
L	0046872	molecular_function	metal ion binding
L	0070207	biological_process	protein homotrimerization
L	0070778	biological_process	L-aspartate transmembrane transport
L	0140009	biological_process	L-aspartate import across plasma membrane
L	1902476	biological_process	chloride transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00713
Number of Residues	16
Details	NA_DICARBOXYL_SYMP_1 Sodium:dicarboxylate symporter family signature 1. PfGDlFVrLLKMLVmP

Chain	Residue	Details
A	PRO45-PRO60

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	216
Details	Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"15483603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	830
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"15483603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	240
Details	Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"15483603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	804
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"15483603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	264
Details	Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"15483603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	252
Details	Transmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"15483603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	240
Details	Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"15483603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	744
Details	Intramembrane: {"description":"Discontinuously helical","evidences":[{"source":"PubMed","id":"15483603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	264
Details	Transmembrane: {"description":"Discontinuously helical; Name=7","evidences":[{"source":"PubMed","id":"15483603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	240
Details	Transmembrane: {"description":"Helical; Name=8","evidences":[{"source":"PubMed","id":"15483603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	60
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17230192","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2NWL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2NWX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KBC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	60
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17230192","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2NWX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17230192","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2NWX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X2S","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)