4OVI
Phenylacetone monooxygenase: oxidised enzyme in complex with APADP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0004499 | molecular_function | N,N-dimethylaniline monooxygenase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| A | 0033776 | molecular_function | phenylacetone monooxygenase activity |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| A | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 36 |
| Details | binding site for residue FAD |
| Chain | Residue |
| A | VAL22 |
| A | TRP55 |
| A | TRP57 |
| A | ASN58 |
| A | CYS65 |
| A | ASP66 |
| A | ILE67 |
| A | TYR72 |
| A | THR117 |
| A | THR118 |
| A | VAL119 |
| A | GLY23 |
| A | ALA149 |
| A | SER150 |
| A | GLY151 |
| A | GLN152 |
| A | LEU153 |
| A | ILE399 |
| A | MET446 |
| A | ILE450 |
| A | N01602 |
| A | CL604 |
| A | GLY25 |
| A | HOH966 |
| A | HOH978 |
| A | HOH994 |
| A | HOH1023 |
| A | HOH1025 |
| A | HOH1031 |
| A | HOH1035 |
| A | PHE26 |
| A | SER27 |
| A | GLU46 |
| A | THR47 |
| A | GLY53 |
| A | VAL54 |
| site_id | AC2 |
| Number of Residues | 34 |
| Details | binding site for residue N01 |
| Chain | Residue |
| A | TYR60 |
| A | ARG64 |
| A | ASP66 |
| A | LEU153 |
| A | PRO159 |
| A | ASN160 |
| A | PHE161 |
| A | GLY193 |
| A | THR194 |
| A | GLY195 |
| A | SER196 |
| A | SER197 |
| A | GLN200 |
| A | ARG217 |
| A | THR218 |
| A | HIS220 |
| A | LYS336 |
| A | ARG337 |
| A | ALA386 |
| A | THR387 |
| A | GLY388 |
| A | TRP501 |
| A | FAD601 |
| A | CL604 |
| A | HOH952 |
| A | HOH956 |
| A | HOH964 |
| A | HOH980 |
| A | HOH991 |
| A | HOH1007 |
| A | HOH1011 |
| A | HOH1019 |
| A | HOH1051 |
| A | HOH1054 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue PGE |
| Chain | Residue |
| A | TYR259 |
| A | GLU272 |
| A | ARG279 |
| A | TYR280 |
| A | GLU283 |
| A | HOH911 |
| A | HOH935 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue CL |
| Chain | Residue |
| A | ARG337 |
| A | FAD601 |
| A | N01602 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue ACT |
| Chain | Residue |
| A | ARG350 |
| A | ASP351 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue GOL |
| Chain | Residue |
| A | ARG34 |
| A | GLU37 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15328411","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21697090","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24443704","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 11 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21697090","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"source":"PubMed","id":"15328411","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21697090","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
